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A probiotic composition beneficial to glucose and lipid metabolism, its preparation and application

A probiotic preparation and glucose and lipid metabolism technology are applied in the field of probiotic compositions with beneficial glucose and lipid metabolism functions, which can solve problems such as inability to achieve and lower blood sugar, and achieve the purpose of lowering blood lipids, improving diabetes symptoms, and protecting islet β-cell function. Effect

Active Publication Date: 2021-04-02
RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although probiotics can improve the intestinal microecological environment, the use of 1-2 strains of Lactobacillus or Bifidobacteria alone cannot effectively reduce blood sugar, let alone achieve the same effect as oral drugs for type 2 diabetes

Method used

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  • A probiotic composition beneficial to glucose and lipid metabolism, its preparation and application
  • A probiotic composition beneficial to glucose and lipid metabolism, its preparation and application
  • A probiotic composition beneficial to glucose and lipid metabolism, its preparation and application

Examples

Experimental program
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Effect test

Embodiment 1

[0062] The following weights of 9 probiotics were mixed to prepare a probiotic composition: 10g Bifidobacterium longum, 10g Bifidobacterium breve, 10g Lactobacillus gasseri, 10g Lactobacillus rhamnosus, 10g Lactobacillus salivarius, 10g Lactobacillus crispatus , 10g Lactobacillus plantarum, 10g Lactobacillus fermentum and 10g Lactobacillus casei. The total number of live lactic acid bacteria in the prepared probiotic composition is not less than 1.0×10 11 cfu / gram.

Embodiment 2

[0064] The following weights of 9 probiotics were mixed to prepare a probiotic composition: 12g Bifidobacterium longum, 10g Bifidobacterium breve, 9g Lactobacillus gasseri, 10g Lactobacillus rhamnosus, 9g Lactobacillus salivarius, 9g Lactobacillus crispatus , 11g Lactobacillus plantarum, 15g Lactobacillus fermentum and 7g Lactobacillus casei. The total number of live lactic acid bacteria in the prepared probiotic composition is not less than 2.0×10 11 cfu / g

Embodiment 3

[0066] The following weights of 9 probiotics were mixed to prepare a probiotic composition: 5g Bifidobacterium longum, 7g Bifidobacterium breve, 20g Lactobacillus gasseri, 4g Lactobacillus rhamnosus, 8g Lactobacillus salivarius, 17g Lactobacillus crispatus , 7g Lactobacillus plantarum, 7g Lactobacillus fermentum and 5g Lactobacillus casei. The total number of live lactic acid bacteria in the prepared probiotic composition is not less than 3.0×10 11 cfu / gram.

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Abstract

The invention relates to a probiotic composition, and discloses a probiotic composition beneficial for a glycolipid metabolic function and a preparation and application of the composition. The probiotic composition comprises some of the following nine probiotics: bifidobacterium longum, bifidobacterium breve, lactobacillus gasseri, lactobacillus rhamnosus, lactobacillus salivarius, lactobacillus crispatus, lactobacillus plantarum, lactobacillus fermentum and lactobacillus casei. Different strains in the probiotic composition cooperate with each other, so that the probiotic composition has thefunction of adjusting glycolipid metabolism, and has certain effect on serum total cholesterol, triglycerides, insulin beta-cell functions and diabetes mellitus improvement.

Description

technical field [0001] The invention relates to a probiotic composition, in particular to a probiotic composition beneficial to glucose and lipid metabolism. Background technique [0002] Diabetes mellitus is a chronic metabolic disorder syndrome caused by defective insulin function. The main clinical manifestations are polydipsia, polyuria, polyphagia and weight loss. After that, it is the third largest disease in the world that seriously threatens human health. The current treatment of diabetes is mainly oral drugs: such as sulfonylureas, glinides, biguanides, thiazolidinediones and α-glucosidase inhibitors. In addition, injecting insulin or insulin analogs is also an effective way to lower blood sugar. However, the above-mentioned drugs are often limited in practical use because of their potential side effects and clinical defects such as subordinate failures. [0003] In order to alleviate and avoid the above-mentioned defects during the use of diabetes drugs, people ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/20A23L33/135A61K35/747A61P3/06A61P3/10A61K35/745
CPCA23V2002/00A61K35/745A61K35/747A23L33/135A23V2200/328A23V2200/3262A61K2300/00
Inventor 宁光王卫庆顾燕云张翼飞杭晓敏张和春张旻夏祎稚
Owner RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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