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Application of baicalin in preparation of medicine for resisting eimeria tenella

A technology of Eimeria and baicalin, which is applied in the field of application of baicalin in the preparation of anti-Eimeria medicaments, to achieve a good anti-Eimeria effect

Inactive Publication Date: 2018-07-13
INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] So far, there is no report that baicalin has anti-Eimeria tenella, and the known properties of baicalin cannot infer whether it has anti-Eimeria tenella

Method used

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  • Application of baicalin in preparation of medicine for resisting eimeria tenella
  • Application of baicalin in preparation of medicine for resisting eimeria tenella
  • Application of baicalin in preparation of medicine for resisting eimeria tenella

Examples

Experimental program
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Effect test

Embodiment 1

[0013] A baicalin powder, the specific preparation process of which is as follows: take 5 g of baicalin (with a content of not less than 99%) and 95 g of starch and mix evenly to obtain the baicalin powder.

[0014] The usage and dosage of the above-mentioned baicalin powder: mix the above-mentioned 100g powder into 100kg feed, and feed according to the daily food intake.

Embodiment 2

[0016] A water-soluble baicalin powder, the specific preparation process of which is as follows: 2.5g of baicalin (with a content of not less than 99%) and 97.5g of glucose are mixed uniformly.

[0017] The usage and dosage of above-mentioned water-soluble powder: dissolve above-mentioned 100g powder in 100 liters of water. Cut off the water for 2 hours before the treatment, and then feed according to the normal drinking water amount.

[0018] The efficacy of baicalin in resisting chicken coccidiosis will be described below in conjunction with specific experiments.

[0019] 1. Experimental materials

[0020] (1) Control drug: conventional anticoccidial drug Sanzi coccidian powder (30% sodium sulfachlorpyrazine, batch number 001010), produced by Shanghai Novartis Animal Health Co., Ltd.

[0021] (2) Test drugs: the baicalin powder provided in Example 1 of the present invention, and the baicalin water-soluble powder provided in Example 2.

[0022] (3) Coccidia oocysts: sporul...

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Abstract

The invention discloses the application of baicalin in preparation of medicine for resisting eimeria tenella. A powder is prepared from baicalin and acceptable ingredients, and is added into fodder tobe blended for feeding chicken according to everyday fodder quantity; or baicalin is prepared into a baicalin water soluble powder to be dissolved into water to feed chicken according to everyday fodder quantity. Animal infection experiments indicate that the anticoccidial index (ACI) of baicalin can reach more than 175, and the baicalin has preferable resistance to eimeria tenella, therefore, anovel application of baicalin medicine is provided.

Description

technical field [0001] The invention belongs to a new application of baicalin, and in particular relates to the application of baicalin in preparing anti-Eimeria tenella medicaments. Background technique [0002] Chicken coccidiosis is the most important disease that seriously endangers the intensive chicken industry production, and the economic loss caused by it is as high as more than 2.5 billion pounds every year. Its pathogen is Eimeria spp of the apicomplexa class, The most harmful of these is Eimeria tenella. Although my country has no accurate statistics on this so far, the most conservative estimate is that the loss should not be less than 2.5 billion RMB. Chemical drug treatment is one of the important measures to control coccidiosis in chickens, but at present chicken coccidiosis has extensive and serious drug resistance, and new anticoccidiosis drugs are urgently needed to be put on the market. [0003] Baicalin (Chinese alias: Baijialing; baicalin; baicalein), ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K9/14A61P33/02
CPCA61K31/7048A61K9/145A61K9/146
Inventor 孙铭飞廖申权戚南山吴彩艳李娟吕敏娜林栩慧胡俊菁于林增刘保臻
Owner INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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