A kind of targeting microcapsule of total alkaloids of Sophora sophorae and preparation method thereof

A Sophora sophora, targeting technology, applied in the field of targeted microcapsules of Sophora sophora total alkaloids and its preparation, can solve the problems of inconsistency of results and no reports of total alkaloids of Sophora sophora, and achieve simple and feasible preparation process and effective treatment The effect of yellow and white scour of piglets

Active Publication Date: 2021-07-09
绿亚生物科技有限公司
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

However, there are few reports on the experimental research of this drug in the prevention and treatment of animal diseases, and the results are not consistent, and the targeted microcapsules of Sophora sophora have not been reported yet.

Method used

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  • A kind of targeting microcapsule of total alkaloids of Sophora sophorae and preparation method thereof
  • A kind of targeting microcapsule of total alkaloids of Sophora sophorae and preparation method thereof
  • A kind of targeting microcapsule of total alkaloids of Sophora sophorae and preparation method thereof

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Embodiment Construction

[0022] Preferred embodiments of the present invention are described below, and it should be understood that the preferred embodiments described here are only used to illustrate and explain the present invention, and are not intended to limit the present invention.

[0023] One, the preparation method of the targeted microcapsule of total alkaloids of Sophora

[0024] 1 material

[0025] Sophora alopecia total alkaloids: Extracted and prepared from the Drug Research Office of Lanzhou Institute of Animal Husbandry and Veterinary Medicine, Chinese Academy of Agricultural Sciences.

[0026] Astragalus polysaccharide 55%: Shaanxi Angsheng Biomedical Technology Co., Ltd.

[0027] Attapulgite clay: Haodi Industry and Trade Co., Ltd., Jingyuan County, Gansu Province.

[0028] 2 Determination method of total alkaloid content in Sophora aphorae

[0029] 2.1 Preparation of reagents

[0030] (1) Prepare a buffer solution with pH=7.6: Take 100 mL of 0.1 mol / L sodium dihydrogen phosphat...

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Abstract

The invention discloses a targeted microcapsule of total alkaloids of Sophora sophora, the core material and wall material of the targeted microcapsule are total alkaloids of sophora sophora and astragalus polysaccharide respectively, and the targeted microcapsule also contains attapulgite clay; and provides its preparation method. The targeted microcapsules have the characteristics of anti-acid, anti-digestion, and easy degradation in the large intestine, and realize the effect of localized drug release in the large intestine. The preparation process is simple and feasible, and it is an ideal animal feed additive that can replace traditional antibiotics. It can effectively treat yellow and white scour of piglets.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicines, and in particular relates to a targeting microcapsule of Sophora sophora total alkaloids and a preparation method thereof. Background technique [0002] Bitter bean alias Buya (translated name in Uighur), bitter bean grass, bitter licorice, etc., is a perennial herb of the genus Sophora in the family Fabaceae. It is mainly distributed in the desert and semi-desert areas of Gansu, Inner Mongolia, Ningxia, Qinghai, Xinjiang and other northwest provinces. Wet area, with good sand-growing characteristics. The total alkaloids of Sophora sophora is its effective active ingredient, which has broad-spectrum antibacterial effect. According to pharmacology of traditional Chinese medicine, Sophora sophora has a wide range of effects such as clearing away heat and dampness, killing insects, relieving asthma, and anticancer. It is clinically used to treat acute bacillary dysentery and amoebic dy...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/52A61K47/36A61K47/02A61P31/04A61P1/00A61P1/12A23K10/30
CPCA61K9/501A61K9/5036A61K36/489A23K10/30
Inventor 梁剑平王震郝宝成梁妍刘宇王学红于鹏郭文柱尚若锋赵凤舞杨珍
Owner 绿亚生物科技有限公司
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