Composition for improving lip lines
A composition and lip wrinkle technology, applied in the directions of skin care preparations, cosmetics, cosmetic preparations, etc., can solve the problems of being easily eaten into the human body, taking away the moisture of the lips, and losing the moisture of the lips, so as to prevent the lips. The effect of aging, improving lip color, enhancing lip elasticity
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Embodiment 1~5
[0028] Examples 1-5 The formula of the lip cream for improving lip lines of the present invention is shown in Table 1.
[0029] Table 1
[0030]
[0031] The preparation method of the lip cream for improving lip lines described in Examples 1 to 5 comprises the following steps: heating shea butter oil, lanolin oil, petrolatum, olive oil, tocopheryl acetate, and liquid paraffin to 90° C., dissolving and mixing Mix evenly to prepare phase A; mix ascorbic acid, panthenol, collagen, rosemary extract, and lycopene evenly to prepare phase B; cool phase A to 47°C, add phase B and mix evenly, cool to room temperature, Vested lip cream.
Embodiment 6
[0041] Stimulus test
[0042] Take 30 healthy rats, weighing 180-220g, both male and female, remove the back hair on both sides before the test, each side 3 × 3cm, and randomly divide them into a test group, a blank control group and a positive control group, with 10 rats in each group. The positive control group uses 2,4-dinitrochlorobenzene, the sensitization uses 1% concentration, and the excitation uses 0.1% concentration; the test group uses the emulsion of Example 5 of the present invention. Get the lip cream of the embodiment of the present invention 1 and apply it to the depilated area on the back, once every other day, totally 3 times. 14 days after the last contact, apply the drug on the same area of the back, observe immediately after removing the drug 6 hours later, and observe whether there is any allergic reaction at 24, 48, and 72 hours. The blank control group and the positive control group were stimulated, contacted and observed in the same way. Test resul...
Embodiment 7
[0044] Efficacy verification
[0045] 1. Test object: select 180 routine volunteers with more serious lip lines on the lips to clinically observe the effect of the lip cream of the present invention. Volunteers were randomly divided into 9 groups, 5 groups were experimental groups 1-5, and 4 groups were control groups 1-4. The experimental groups corresponded to the lip creams prepared in Examples 1-5, and the control groups corresponded to the lip creams prepared in Comparative Examples 1-4. lip cream.
[0046] 2. How to use: In the morning when the lips are clean, gently apply the lip cream of the present invention to the lips. This product can be used alone or before applying colored lipstick. After covering the lips with a clean hot and humid towel for 2 to 3 minutes at night, apply the lip cream of the present invention to the lips gently. Store at room temperature. Data were recorded after 1 month of use at the same time. The results are shown in Table 2 below.
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