Traditional Chinese medicine component prescription for improving pig immunosuppressive state and its preparation method and application

Abstract

The invention belongs to the technical field of pharmaceutic preparations containing algae, moss, fungi or plants or derivatives thereof, for example, uncertain structures of traditional herbs, and discloses a Chinese herbal medicinal ingredient prescription capable of improving swine immunosuppression and a preparation method and application of the Chinese herbal medicinal ingredient prescription. The mass ratio of corilagin, cordycepin, icariin and peoniflorin is 1-4: 1-4: 1-4: 1-4. The corilagin, the cordycepin, the icariin and the peoniflorin are added with normal saline to prepare liquidmedicine with the total concentration being 2 mg / mL according to the mass ratio of 1-4: 1-4: 1-4: 1-4. The specific antibody titer of animals can be improved effectively, the viral load is reduced, the number and activity of immunocytes and immunotransmitters are increased, growth and development of immune organs are promoted, the immunologic function and the disease resistance of the animal can be enhanced comprehensively, toxic and side effects of vaccines, chemical drugs and antibiotics and potential safety hazards of food are overcome, the research and development prospect is promising, and clinical application is wide.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations containing undetermined structures from algae, moss, fungus or plants or derivatives thereof, such as traditional herbal medicines, and particularly relates to a traditional Chinese medicine composition formula for improving the immune suppression state of pigs and its preparation method and application. Background technique [0002] At present, the commonly used existing technologies in the industry are as follows: at present, my country's pig production is facing the increasingly severe threat of epidemic diseases, the incidence is complex and changeable, the production risk is increasing day by day, the control cost is significantly increased, and the economic loss is immeasurable. An important reason for this is the prevalence of immunosuppressive diseases in pig herds. Porcine immunosuppressive disease is a type of disease that leads to a significant decline in the body's ...

AI Technical Summary

Problems solved by technology

PCV2 and PRRSV infection cause the most common and typical immunosuppressive diseases in veterinary clinics, which directly lead to the use of a large number of drugs in the process of disease diagnosis and treatment, resulting in the rapid development of drug resistance of pathogenic microorganisms; at the same time, the specific and non-specific immunity of animals Decreased, unable to respond to various vaccines, or the antibody titer produced is low, resulting in low pathogenicity pathogens or attenuated vaccines may also infect pigs; more serious is the mixed infection brought by PCV2 and PRRSV , making the disease more complicated, sometimes causing new syndromes, even to the point of being difficult to control, causing huge economic losses to pig production, and at the same time bringing hidden dangers to public health and safety

[0003] In summary, the existing problems in the prior art are: the existing treatment methods for PCV2 and PRRSV infection lead to the use of a large number of drugs in the process of disease diagnosis and treatment, causing the drug resistance of pathogenic microorganisms to change rapidly; The heterosexual immunity is reduced, unable to respond to various vaccines, or the antibody titer produced is low, resulting in low pathogenicity pathogens or attenuated vaccines may also infect pigs; more serious is caused by PCV2 and PRRSV, etc. The mixed infection of pigs makes the disease more complicated, sometimes causes new syndromes, and even reaches a level that is difficult to control, causing huge economic losses to pig production, and at the same time bringing hidden dangers to public health and safety

[0004] The difficulty and significance of solving the above-mentioned technical problems: the present invention has found through a large number of experiments that the combination of Chinese medicine components such as Corilagin has the effect of releasing immunosuppression and regulating immune function. The prior art has not disclosed that this Chinese medicine composition has the effect of releasing immune suppression and regulating immune function. The role of immune function, and the traditional Chinese medicine composition formula has not been used as a feed additive instead of antibiotics in livestock and poultry breeding. Based on this, this application is made

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