Drug coated balloon dilating catheter and process thereof

A technology for dilating catheters and balloons, applied in the direction of balloon catheters, catheters, coatings, etc., to achieve the effects of short tissue absorption time, high tissue safety, and high release rate

Inactive Publication Date: 2018-11-06
JW MEDICAL SYSTEMS LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, paclitaxel itself achieves the purpose of inhibiting the proliferation of smooth muscle cells by acting on cells to cause apoptosis or death, that is, paclitaxel has certain cytotoxicity.

Method used

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  • Drug coated balloon dilating catheter and process thereof
  • Drug coated balloon dilating catheter and process thereof
  • Drug coated balloon dilating catheter and process thereof

Examples

Experimental program
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Embodiment Construction

[0040] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0041] figure 1 , figure 2 A kind of medicine balloon expansion catheter shown, comprises medicine balloon 2, outer lumen tube 4, inner lumen tube 6, joint 11; The surface of medicine balloon 2 is coated with drug coating; Release medicine in drug coating It is rapamycin derivative BA9, and the drug-releasing carrier is polyethylene oxide;

[0042] The abbreviation of BA9 is Biolimus A9, which is an anti-proliferation drug independently developed by the company. Its English name is Umirolimus, and its Chinese name is Umirolimus. The chemical formula is:

[0043]

[0044] Usually, the smaller the drug particles, the faster the late lumen loss. Therefore, through the drug particle screening technology, only 10-30 micron BA9 particles are retained to ensure the absorption efficiency. Because BA9 particles of 10-30 microns can stay...

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Abstract

The invention discloses a drug coated balloon dilating catheter and a process thereof. The drug coated balloon dilating catheter comprises a drug coated balloon, an outer cavity tube, an inner cavitytube and a connector. The surface of the drug coated balloon is coated with a drug coating, a release drug in the drug coating is a sirolimus derivative BA9, and a carrier of the release drug is polyethylene oxide. A manufacturing process of the drug coated balloon dilating catheter includes steps of catheter assembly and drug coating. The drug coated balloon has advantages of short tissue absorption time, high drug absorption efficiency and high drug coated balloon release rate, and high tissue safety is realized. Compared with an existing taxol drug coated balloon, the drug coated balloon has advantages of promising application prospect.

Description

technical field [0001] The invention relates to a balloon catheter and a process, in particular to a drug balloon dilation catheter and a process thereof, and belongs to the technical field of medical devices. Background technique [0002] The main way to treat coronary heart disease is to implant drug-eluting coronary stents (DES). After implanting DES, patients need to take long-term oral antithrombotic drugs and affect subsequent surgical treatment. Moreover, DES may have the problem of late stent thrombosis. Therefore, as a new concept of interventional therapy, "intervention without implantation" is being accepted by more and more clinicians and patients, and drug balloon (DCB) is a new product under this concept of interventional therapy. [0003] As a new type of intravascular drug release technology, drug balloons are coated with anti-proliferative drugs on the surface of the balloon. The drug carried on the surface is quickly transferred to the blood vessel wall an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M25/10A61L29/08
CPCA61M25/1002A61L29/08A61L29/085A61L2300/216A61L2300/416A61L2300/602A61M25/1029A61M2025/1031A61M2025/105C08L71/02
Inventor 韩雅玲徐凯李毅王丹潘远航陈湘
Owner JW MEDICAL SYSTEMS LTD
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