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TB treatment device with therapeutic channel

A treatment device and channel technology, which is applied in drug devices, other medical devices, medical science, etc., can solve the problems of multi-drug-resistant tuberculosis patients who cannot be cured, Mycobacterium tuberculosis residues, and more drugs for treatment, etc.

Inactive Publication Date: 2018-12-25
北京赛舒特医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are the following defects in the chemotherapy of multidrug-resistant tuberculosis patients by conventional routes of administration (oral, intramuscular injection, intravenous injection): ① long treatment cycle: for an ordinary tuberculosis patient, the treatment cycle is generally 6 months; for multidrug-resistant tuberculosis patients The treatment cycle is 18 to 24 months, or even 36 months, which is 3 to 6 times that of ordinary tuberculosis patients; as one of the most important second-line drugs, injections (such as kanamycin, capreomycin, etc.) are used for at least 6 months over a month
② There are many drugs for treatment, and the incidence of adverse reactions is high: there are about 4 to 5 first-line drugs for the treatment of common tuberculosis patients, and the adverse reaction rate is not high; while for multidrug-resistant tuberculosis patients, there are at least 5 to 6 drugs, and the adverse reaction rate is high. Higher second-line anti-TB drugs, such as capreomycin, cycloserine, prothionamide, etc.
③Low cure rate: At present, the cure rate of ordinary tuberculosis patients is more than 85%, and it has exceeded 90% in my country; while the highest cure rate of multidrug-resistant tuberculosis patients is only about 50-60%. Half of MDR-TB patients are uncured
[0011] In the interventional treatment of pulmonary tuberculosis, although Mycobacterium tuberculosis in the target cavity of pulmonary tuberculosis is aspirated during the operation, there is still a risk of residual Mycobacterium tuberculosis bacteria, and there is already a risk of complications such as pneumothorax during the puncture

Method used

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  • TB treatment device with therapeutic channel
  • TB treatment device with therapeutic channel
  • TB treatment device with therapeutic channel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] figure 1 It is a structural schematic diagram of the lung treatment device according to Embodiment 1 of the present invention. The lung treatment device 10 with a treatment channel in this embodiment is composed of a blocking part 11, a channel part 12 and a switch part 13. The blocking part 11 has a cylindrical side in the middle and two ends of the cylindrical side and are coaxial with the cylindrical side. The two conical end faces of the cylinder, the cylindrical side and the two conical end faces are integrally formed, the channel part 12 runs through the plugging part 11 and is located at the central axis of the cylindrical side and the conical end face, and the two ends of the channel part 12 are flush with the plugging part 11 The switch part 13 is arranged on one end of the channel part 12, and the switch part 13 closes this end of the channel part 12 under normal conditions, and at this moment, the said blocking part 11 is airtight along the length direction o...

Embodiment 2

[0050] See Figure 4 , the lung treatment device 20 with the treatment channel in this embodiment is made up of a blocking part 21, a channel part 22, a first switch part 23 and a second switch part 24, and the blocking part 21 of this embodiment includes a frame 211 and covers the frame The film layer 212 on the surface of 211. The main difference between this embodiment and Embodiment 1 is that switch components are provided at both ends of the channel component 22 . and, if Figure 4 As shown, the second switch part 24 does not use a bell mouth, but a contracted flat mouth structure.

[0051] The first switch part 23 and the second switch part 24 of the lung treatment device 20 with the treatment channel of the present embodiment are initially closed, so the two ends of the channel part 22 are closed, so that the sputum accumulation in the tuberculosis target cavity area can be avoided. remain within the channel member 22, thereby preventing blockage of the channel membe...

Embodiment 3

[0054] The lung treatment device 30 with a treatment channel in this embodiment is composed of a blocking part 31, a channel part 32, a switch part 33 and a control part 35. The blocking part 31 of this embodiment includes a frame 311 and a film layer covered on the surface of the frame 311 312, such as Figure 5 shown.

[0055] The difference between this embodiment and Embodiment 1 is that the shape of the blocking member 31 is a hollow cylinder, and the control member 35 is integrated on the switch member 33, and the switch member 33 and the control member 35 are arranged eccentrically and arranged on the block member 31. edge, the control part 35 also acts as a grip and connection means for the recycling process. The shape of the control part 35 is, for example, as Figure 5 Hook shape shown.

[0056] In order to further cooperate with the further treatment of the target cavity of pulmonary tuberculosis, the control part 35 can be grasped and fixed by the grasper or bio...

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Abstract

The invention discloses a TB treatment device with therapeutic channel, which mainly comprises a blocking component, a channel component and one or two switch components. The side of the blocking component is attached and positioned on the inner wall of the bronchi. The channel component extends through the blocking component; the blocking component is air-tight in a direction along the length ofthe bronchi except the space reserved for the channel component. The one or two switch components are arranged at one end or both ends of the channel component in which the switch component is closedin default and closes the end of the channel component. Once the switch member is opened by an external force, the channel component is in a through connection to make the TB treatment device pass along the length direction of the bronchi. Placing the TB treatment device in the bronchi near the hollow area of the mycobacterium tuberculosis can isolate external air and provide a channel for pumpingor delivering drug treatment to the residual mycobacterium tuberculosis in the targeted hollow area.

Description

technical field [0001] The invention relates to an interventional treatment device, in particular to a lung treatment device with a treatment channel which can block the target cavity area of ​​pulmonary tuberculosis so as to isolate oxygen. Background technique [0002] Tuberculosis is a disease that seriously endangers human health. It is a pulmonary infectious disease caused by Mycobacterium tuberculosis. After Mycobacterium tuberculosis infects the human body, it is mostly in a latent state or a persistent infection state. It can evade the host's defense in the infected host cells to multiply and achieve a delicate balance with the host. At any time in the life of the infected person are likely to get sick. Typically, 10% of infected people will develop active tuberculosis. An untreated active tuberculosis patient can infect 10-15 people a year. [0003] Since the invention of antibiotics, as well as the advancement of tuberculosis control theory and technology, clini...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B17/12A61M31/00
CPCA61M31/00A61B17/1204A61B17/12145A61B17/12195A61B2017/00867A61B2017/00862A61B2017/00889
Inventor 王仲元王正斌吴羽纶周则红
Owner 北京赛舒特医疗器械有限公司