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Lung therapy device

A therapeutic device and consistent technology, applied in the field of medical devices, can solve the problems of high incidence of adverse reactions, inability to cure multidrug-resistant tuberculosis patients, residual Mycobacterium tuberculosis, etc.

Pending Publication Date: 2019-05-28
北京赛舒特医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chemotherapy for MDR-TB patients with conventional routes of administration (oral, intramuscular, intravenous) has the following defects: ①Long treatment cycle: for an ordinary TB patient, the treatment cycle is generally 6 months; for MDR-TB patients The treatment cycle is 18 to 24 months, or even 36 months, which is 3 to 6 times that of ordinary tuberculosis patients; as one of the most important second-line drugs, injections (such as kanamycin, capreomycin, etc.) are used for at least 6 months over a month
② There are many drugs for treatment, and the incidence of adverse reactions is high: there are about 4 to 5 first-line drugs for the treatment of common tuberculosis patients, and the adverse reaction rate is not high; while for multidrug-resistant tuberculosis patients, there are at least 5 to 6 drugs, and the adverse reaction rate is high. Higher second-line anti-TB drugs, such as capreomycin, cycloserine, prothionamide, etc.
③Low cure rate: At present, the cure rate of ordinary tuberculosis patients is more than 85%, and it has exceeded 90% in my country; while the highest cure rate of multidrug-resistant tuberculosis patients is only about 50-60%. Half of MDR-TB patients are uncured
This method is currently mainly used clinically for cavities that are not suitable for fiberoptic bronchoscopy or cannot be reached by fiberoptic bronchoscopy, but there is a risk of puncture complications such as pneumothorax
[0009] In summary, the interventional treatment of pulmonary tuberculosis through the tracheobronchial route only uses the interventional method to deliver drugs to the target cavity of pulmonary tuberculosis, but it does not actually achieve the effect of completely killing Mycobacterium tuberculosis. The risk of dissemination; in the interventional treatment of pulmonary tuberculosis percutaneous puncture, although the sputum in the target cavity of pulmonary tuberculosis is aspirated during the operation, there is still a risk of residual Mycobacterium tuberculosis. Risk occurs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] figure 1 It is a schematic side view of the lung therapy device 1 according to Embodiment 1 of the present invention.

[0028] figure 1 It can be seen from the figure that the lung treatment device 1 is composed of a one-way valve 10 , a frame 11 and a film layer 12 covering the surface of the frame 11 .

[0029] Wherein, the frame 11 is a combination of a two-stage tubular structure formed around a central axis L surrounded by a plurality of various types of poles 113 and a conical structure connecting the two tubular structures; wherein the frame 11 has a proximal end 111, Distal end 112, and wherein a part of pole 113a forms a first tubular structure near the far end 112 of frame 11, and another part of pole 113b forms a second tubular structure near the proximal end 111 of frame 11, and said tapered structure is connected by The proximal end of the first tubular structure and the proximal end of the second tubular structure consist of a plurality of struts 113c. ...

Embodiment 2

[0044] Since some bronchi are relatively short in length, it is required that the axial length of the lung therapy device inserted into the bronchi is sufficiently short.

[0045] In the structure of the frame 11a of the present embodiment, the outer part of the intersection point of each pair of intersecting columns 113 is called the apex 1131.

[0046] As in this example Figure 5 As shown in the cross-sectional view of the frame 11a, the projections of the rods 113b at the proximal end 111a of the frame 11a, the rods 113a at the far end 112 of the frame 11, and the rods 113c between them on the central axis L all have overlapping.

[0047] Such arrangement can effectively shorten the length of the device while ensuring that the one-way valve 10 will not be deformed by the extrusion force in the second tubular structure formed by the proximal end 111a of the frame 11a.

[0048] After the lung treatment device 1a is placed in the bronchus 2, since the length of the frame 11...

Embodiment 3

[0050] Since the lung treatment device is placed in the bronchi, it needs to be firmly fixed by the radial support force of the poles 113a at the far end of the frame. Therefore, the more the poles 113a at the far end of the frame, the more secure it is. However, the surface of the frame is covered with a film After the layer 12, more struts 113a will increase the contracted volume of the lung therapy device, and the thickness of the film layer 12 is generally greater than 10 microns. This requires that the number of poles 113a of the frame should not be too large.

[0051] Figure 7 is a schematic structural diagram of a frame 11b according to an embodiment of the present invention. Wherein, the vicinity of the proximal end 111b of the frame 11b includes two rows of converging poles 113b, such as Figure 7 The dotted line box in the frame shows the first row of intersection poles, the first row of intersection poles 113b includes 4 sets of intersection poles in the circumfe...

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Abstract

The invention discloses a lung therapy device. The lung therapy device is formed by a one-way valve, a frame and a film layer covering the surface of the frame. Each of a far end of the frame and a near end of the frame comprises at least one row of intersection pillar rods. Each row of the intersection pillar rods comprises at least two groups of the intersection pillar rods. The exterior of an intersection point of the intersected pillar rods in pairs in each group is called as a vertex. A positioning sphere head is formed on each vertex of the far end of the frame. The pillar rods at the far end or the near end of the frame form a tubular structure. A diameter of a first tubular structure formed near the far end of the frame by a part of the pillar rods is greater than a diameter of a second tubular structure formed near the near end of the frame by the other part of the pillar rods. In addition, one part of the pillar rods is connected with the near end of the first tubular structure and the near end or a middle part of the second tubular structure, the part of the pillar rods is at least upwards overlapped with the pillar rods for forming the second tubular structure in a center shaft.

Description

technical field [0001] The invention relates to a medical device, in particular to a device for treating a patient's lung in interventional therapy, especially a device for treating a patient's pulmonary tuberculosis, especially for multidrug-resistant tuberculosis. Background technique [0002] Tuberculosis is a disease that seriously endangers human health. It is a pulmonary infectious disease caused by Mycobacterium tuberculosis. After Mycobacterium tuberculosis infects the human body, it is mostly in a latent state or a persistent infection state. It can evade the host's defense in the infected host cells to multiply and achieve a delicate balance with the host. At any time in the life of the infected person are likely to get sick. Typically, 10% of infected people will develop active tuberculosis. An untreated active tuberculosis patient can infect 10-15 people a year. [0003] Since the invention of antibiotics, as well as the advancement of tuberculosis control the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F5/00A61M31/00
Inventor 王仲元王正斌吴羽纶周则红
Owner 北京赛舒特医疗器械有限公司