A kind of composition for resisting hp infection and promoting the balance of stomach flora and application thereof

Abstract

The invention provides a composition for resisting Hp infection and promoting the balance of gastric microflora and its application. In parts by weight, it includes 200-900 parts of mannose oligosaccharides, 100-400 parts of high molecular weight chitosan oligosaccharides and 100-400 parts of chitosan. The composition has anti-Hp infection resistance, synergistically promotes the balance of the flora in the stomach, and has a significantly higher effect than the three alone. The composition can effectively maintain the balance of gastric flora and prevent Hp infection for healthy people without Hp infection and gastric diseases; for patients with simple Hp infection without gastric diseases, it can significantly inhibit Hp and promote gastric flora at the same time. Balance, effectively avoid patients complicated by gastric diseases; for patients infected with Hp and associated gastric diseases, it can significantly inhibit Hp, and at the same time regulate the balance of gastric flora, effectively avoid the further development of gastric diseases, and improve their clinical disease and improve the quality of life of patients.

Description

technical field [0001] The invention belongs to the field of medical and health food, in particular to a composition for promoting the balance of microflora in the stomach, and relates to a compatible composition of oligomannose, high molecular weight chitosan oligosaccharide and chitosan, and a preparation method and application thereof. Background technique [0002] Gastric cancer is the third leading cause of cancer-related death in the world. A large number of current studies believe that Helicobacter pylori (Hp) infection is the most important risk factor for gastric cancer. It can promote precancerous lesions (such as gastric atrophy, intestinal metaplasia, and dysplasia). ) development, eventually leading to the occurrence of gastric cancer. H. pylori infection is very common, the global infection rate is about 50%, of which 1-3% of infected people will develop gastric cancer. [0003] At present, the main researches believe that H. pylori is an important pathogenic ...

AI Technical Summary

Problems solved by technology

[0005] The research found that the main causes of gastric microecological imbalance are: (1) During the course of antibiotic treatment, the pathogenic bacteria were inhibited, and the survival of normal flora was also destroyed; (2) The bacteria caused by different physiological states of the host The group defense barrier is destroyed, which may cause the imbalance of normal flora or transfer to other abnormal parts; (3) Abnormal gastric motility leads to the formation of flora imbalance; (4) Single diet or fiber-free food may affect the flora (5) Damage to the immune barrier of the gastrointestinal tract may cause aerobic and anaerobic bacteria to proliferate and disrupt the balance of the flora