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A composition for treating gynecological inflammation and its application in external composition

A technology of gynecological inflammation and composition, which is applied in the field of composition for treating gynecological inflammation, and can solve problems such as unsatisfactory treatment of gynecological inflammation

Active Publication Date: 2020-12-01
HANYI BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Although a series of pharmaceutical compositions containing cannabidiol and cannabidiol have been developed, none of the existing compositions can meet the treatment requirements for gynecological inflammation.

Method used

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  • A composition for treating gynecological inflammation and its application in external composition
  • A composition for treating gynecological inflammation and its application in external composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The extraction of embodiment 1 cannabidiol

[0036] 1) Wash and air-dry the raw material hemp leaves;

[0037] 2) pulverize the above-mentioned air-dried raw materials to 40 mesh;

[0038] 3) adding 8 times the amount of 95% ethanol to the obtained powder according to the mass volume ratio, and extracting by cold soaking for 3 times, each time for 1 hour;

[0039] 4) Combine extracts and decolorize;

[0040] 5) concentrated under reduced pressure to a relative density of 1.05;

[0041] The obtained cannabidiol extract, wherein the cannabidiol content is 99.5% by mass percentage.

[0042] It should be noted that the descriptions such as "8 times the amount" in the present invention mean that the volume of the extraction solvent used is 8 times the mass of the extraction part. For example, the extraction part of cannabis is 1g, and the amount of extraction solvent is 8ml.

Embodiment 2

[0043] The extraction of embodiment 2 cannabidiol

[0044] 1) Wash and air-dry the raw material cannabis flowers and leaves;

[0045] 2) pulverize the above-mentioned air-dried raw materials to 40 mesh;

[0046] 3) Add 10 times the amount of absolute ethanol to the obtained powder according to the mass volume ratio and extract by cold soaking for 3 times, each time for 1 hour;

[0047] 4) Combine the extracts, decolorize and concentrate;

[0048] 5) Take column chromatography, use silica gel as a packing column, load the extract through the column, the mobile phase is petroleum ether and diethyl ether at 80:20, and the flow rate is 3.0ml / min;

[0049] 6) Collect the effluent containing the cannabidiol component, and remove the solvent by rotary evaporation to obtain a cannabidiol extract, wherein the cannabidiol content is 97.5% by mass percentage.

[0050] Promptly obtain the cannabidiol extract, wherein the cannabidiol content is 99% by mass percentage.

Embodiment 3

[0051] The preparation of the external patch of embodiment 3 prevention and / or treatment gynecological inflammation

[0052] An external drug for preventing and / or treating gynecological inflammation, the external drug is a patch-like external drug, the backing layer is non-woven fabric, the protective layer is anti-sticking paper, and the cannabidiol and secondary The mass ratio of cannabidiol is 0.2:1, the carrier of the drug storage layer is a polymer hydrogel, the mass ratio of the mixture of cannabidiol and cannabidiol to the carrier is 1:5, and the high Molecular hydrogel is made by mixing sodium carboxymethyl cellulose, glycerin, water and aluminum oxide at a mass ratio of 10:30:40:0.1. The penetration enhancer in the carrier is ginger oil, and the mass ratio of ginger oil to carrier is 2:7.

[0053] After mixing cannabidiol and cannabidiol, ginger oil is added to the mixture of cannabidiol and cannabidiol, stirred evenly, then mixed with polymer hydrogel, and then the...

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Abstract

The invention discloses a composition for preventing and / or treating gynecologic inflammation. The composition comprises cannabidiol, cannabidivarin and a carrier, wherein the mass ratio of the cannabidiol to the cannabidivarin is (0.2 to 10):1. The defect of shortage of a composition containing cannabidiol substances for effectively preventing and / or treating gynecologic inflammation in the priorart is overcome. Meanwhile, the composition provided by the invention can also be used for preparing a female sanitation article for preventing and / or treating gynecologic inflammation.

Description

technical field [0001] The present invention relates to a composition for treating gynecological inflammation, in particular to the application of a composition containing cannabidiol and cannabidiol in the preparation of external medicines for preventing and / or treating gynecological inflammation and feminine hygiene products. Background technique [0002] Gynecological inflammation is a common disease of women, which refers to the inflammation of the female internal genitalia and its surrounding connective tissue and pelvic peritoneum. Decreased immune function, endocrine changes or invasion of exogenous pathogenic bacteria can lead to inflammation. Gynecological inflammation seriously affects women's physical and mental health. [0003] Cannabidiol (CBD) is extracted from the natural plant cannabis. It has anticonvulsant, sedative hypnotic, anti-anxiety, anti-psychotic, anti-inflammatory and neuroprotective effects. It has no psychoactive effect, and the binding ability ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/05A61P15/00A61P15/02A61P29/00A61L15/44A61L15/40
CPCA61K9/0014A61K31/05A61L15/40A61L15/44A61L2300/216A61L2300/41A61K2300/00
Inventor 于朝晖张可谭昕
Owner HANYI BIO TECH CO LTD
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