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Aerosol

An aerosol and penetrant technology, applied in the field of medicine, can solve the problems of lower acceptance of tasteless products, achieve the effect of increasing market value, filling sensory loss, and improving acceptance

Pending Publication Date: 2020-04-14
YUNNAN HEMPSON BIO-TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide an aerosol, adding small molecular aroma components, to solve the problem that the tasteless cannabidiol products reduce the acceptance of the tasteless products by patients who originally used natural medical marijuana

Method used

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Effect test

Embodiment 1

[0026] On the basis of comparative example 1, increase industrial hemp flower and leaf essential oil, industrial hemp flower and leaf essential oil obtains industrial hemp flower and leaf essential oil through initial extraction and fine extraction of industrial hemp flower and leaf, wherein,

[0027] Initial extraction: supercritical extraction of industrial hemp, adding an entrainer in the supercritical extraction step, the entrainer can be at least one of ethanol, n-hexane, cyclohexane or ethyl acetate, the entrainer The mass ratio of the amount of the agent to the material is 0.1-10:100; the initial extraction step is carried out in the extraction kettle, the supercritical carbon dioxide fluid flow rate is an extraction kettle volume every 3-10 minutes, and the temperature in the extraction kettle is 25-60 °C, the pressure in the extraction kettle is 10-40MPa, the extraction time is 20-360min, and the initial extract is obtained;

[0028] Fine extraction: Chromatographic t...

Embodiment 2

[0031] On the basis of Comparative Example 1, increase the essential oil of industrial hemp flowers and leaves, the essential oil of industrial hemp flowers and leaves is the first fraction obtained by rectifying the flowers and leaves of industrial hemp, and the specific method of said rectification is Extract the primary extract from the ground cannabis leaf powder with an organic solvent, and place the extract at 110-190°C for rectification. The organic solvent includes gasoline, n-hexane, cyclohexane, alcohol, chloroform or ethyl acetate.

[0032] Among them, the organic solvent is cyclohexane, and when the rectification temperature is 155°C, the effect is the best. The extraction rate of the essential oil of industrial hemp flowers and leaves can reach 0.93% of the total weight of industrial hemp flowers and leaves. The proportion of hemp leaf essential oil can reach 78.7%.

Embodiment 3

[0034] On the basis of Comparative Example 1, the essential oil of industrial hemp flowers and leaves is added, and the flowers and leaves of industrial hemp are dried at 90-120°C until the water content is less than 10%, and then crushed to 50-200 mesh, and mixed according to the weight of water Boil together at a ratio of 1:1-2, co-distill, and the upper component obtained after the distillate is condensed and stratified is the essential oil of industrial hemp flowers and leaves, wherein the weight ratio of industrial hemp flowers and leaves to water is 1:1- 2.

[0035] Among them, the flowers and leaves of industrial hemp are dried at 105°C until the water content is less than 8%, then crushed to 70-80 mesh, and boiled at a weight ratio of 1:1.5 with water, the effect is the best. The extraction rate of the essential oil of industrial hemp flowers and leaves can reach 0.91% of the total weight of industrial hemp flowers and leaves, and the proportion of identified aroma com...

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Abstract

The invention discloses an aerosol comprising industrial hemp floral leaf essential oil and medicinal components. The industrial hemp floral leaf essential oil added in the invention only contains micromolecular aromatic components and does not contain diterpenoid compounds such as cannabidiol, tetrahydrocannabinol and other medicinal active components, so that the biological activity of an addedobject is not obviously influenced. However, after the industrial hemp floral leaf essential oil is added, all odorless cannabinol products have the symbolic aroma of natural industrial hemp, the sensory deficiency, psychological comfort and implication effects are supplemented, and the market value of the original products and the cognition degree of consumers can be greatly improved. The industrial hemp floral leaf essential oil is added into the odorless cannabinol aerosol, so that the acceptability of patients using natural medical hemp to odorless products can be improved.

Description

technical field [0001] The invention relates to the field of medicine, in particular to an aerosol. Background technique [0002] The use of marijuana as a drug and medicine can be traced back to before 440 AD, but in the past it was the psychoactive drug, tetrahydrocannabinol (THC, Tetrahydrocannabinol). Due to the hallucinogenic and psychotic side effects of THC, its medical application is limited. In the past ten years, with the research and discovery of the new pharmacological mechanism of cannabidiol (CBD, Cannabidiol), the non-psychoactive component of cannabis, the world has restarted the research and application boom of cannabinoids under the leadership of Europe and the United States, especially It is a research on cannabidiol extracted from low THC and low toxicity industrial hemp. Modern pharmaceutical research has proved that cannabidiol is opposite to THC. Cannabidiol can treat pain, epilepsy, convulsions, psychosis, and anti-depression, with mild side effects...

Claims

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Application Information

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IPC IPC(8): A61K36/60A61K31/05A61K9/12A61K47/46A61P25/08A61P25/24
CPCA61K9/12A61K31/05A61K36/60A61K47/46A61K2236/331A61K2236/37A61P25/08A61P25/24
Inventor 项伟顾文云李铖
Owner YUNNAN HEMPSON BIO-TECH CO LTD
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