Blood enrichment nutri-gel granules easy to absorb and preparation method thereof

A technology for Shengxuebao and granules, which is applied to the easily absorbed Shengxuebao granules and the field of preparation thereof, can solve the problems of unfavorable absorption and transformation, agglomeration and agglomeration of extracts, susceptibility to thermal denaturation, etc. The effect of improving the efficacy of the drug

Inactive Publication Date: 2019-04-16
谈发金 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The following problems still exist in the existing Shengxuebao granule preparation method: 1. The medicinal materials of Radix Polygoni Multiflori, Ligustrum lucidum, Astragalus, and Dog Rib are bitter and astringent, and the prepared granules have a bitter taste when brewed and taken, and a large amount of water needs to be added. 2. In the process of washing, decocting and extracting Chinese herbal medicines, double the amount of water will be added, and the concentrated extract will agglomerate and agglomerate, making the dry extract powder after spray drying larger in particle size and Wrapped with water, it is not conducive to the absorption and transformation of the human body, and it will undergo hydrolysis and deterioration during storage; 3. The inlet temperature of the spray dryer is as high as 180-240°C, and the Chinese herbal medicine extract will be overheated and cause pores. The heat-sensitive substances, proteins, Active ingredients such as vitamins are easily denatured by heat, and lose their activity after returning to room temperature, greatly reducing the efficacy

Method used

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  • Blood enrichment nutri-gel granules easy to absorb and preparation method thereof

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Effect test

Embodiment 1

[0049] An easy-to-absorb Shengxuebao granule, comprising the following raw materials in parts by weight: 14 parts of Polygonum multiflorum, 17 parts of Ligustrum lucidum, 16 parts of mulberry, 17 parts of Eclipta, 13 parts of white peony, 12 parts of Astragalus, and 14 parts of dog spine ;

[0050] The preparation method of the Shengxuebao granule comprises the following steps:

[0051] (1) Pretreatment: Mix Polygonum multiflorum and black bean juice according to the mass ratio of 10:1, steam until the inside and outside are tan, dry and crush into soybean size for later use; Wash the Eclipta chinensis with water, dry it for later use; fry the dog ridge until it is crispy yellow, and there is no golden fluff left on the edge of one side, take it out for later use;

[0052] (2) One-time ultrafine grinding: Mix and stir the pretreated Qiwei Chinese medicinal materials evenly, pre-grind them into granules, pass through a 20-40 mesh sieve, freeze at -5°C for 10 minutes, put them ...

Embodiment 2

[0058] An easy-to-absorb Shengxuebao granule, comprising the following raw materials in parts by weight: 15 parts of Radix Polygoni Multiflori, 18 parts of Ligustrum lucidum, 17 parts of mulberry, 16 parts of Eclipta chinensis, 14 parts of Radix Paeoniae Alba, 14 parts of Radix Astragali, and 12 parts of dog spines ;

[0059] The preparation method of the Shengxuebao granule comprises the following steps:

[0060] (1) Pretreatment: Mix Polygonum multiflorum and black bean juice according to the mass ratio of 10:1, steam until the inside and outside are tan, dry and crush into soybean size for later use; Wash the Eclipta chinensis with water, dry it for later use; fry the dog ridge until it is crispy yellow, and there is no golden fluff left on the edge of one side, take it out for later use;

[0061] (2) One-time ultrafine grinding: Mix and stir the pretreated Qiwei Chinese medicinal materials evenly, pre-grind them into granules, pass through a 20-40 mesh sieve, freeze at -5...

Embodiment 3

[0067] An easy-to-absorb Shengxuebao granule, comprising the following raw materials in parts by weight: 15 parts of Radix Polygoni Multiflori, 18 parts of Ligustrum lucidum, 16 parts of mulberry, 15 parts of Eclipta chinensis, 14 parts of Radix Paeoniae Alba, 15 parts of Radix Astragali, and 14 parts of dog spines ;

[0068] The preparation method of the Shengxuebao granule comprises the following steps:

[0069] (1) Pretreatment: Mix Polygonum multiflorum and black bean juice according to the mass ratio of 10:1, steam until the inside and outside are tan, dry and crush into soybean size for later use; Wash the Eclipta chinensis with water, dry it for later use; fry the dog ridge until it is crispy yellow, and there is no golden fluff left on the edge of one side, take it out for later use;

[0070] (2) One-time ultrafine grinding: Mix and stir the pretreated Qiwei Chinese medicinal materials evenly, pre-grind them into granules, pass through a 20-40 mesh sieve, freeze at -5...

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Abstract

The invention discloses blood enrichment nutri-gel granules easy to absorb and a preparation method thereof and relates to the technical field of blood enrichment preparations. By adopting an existingformula, the blood enrichment nutri-gel granules are prepared through pre-treatment, primary ultrafine pulverization, extraction and concentration, hot steam drying, freeze drying, secondary ultrafine pulverization, granulation and sieving, the heat-sensitive active ingredients in traditional Chinese medicinal material ingredients can be destroyed and more than 97% of moisture in the medicinal material powder can also be removed by integrating hot steam drying and freeze drying, the fine powder obtained through ultrafine pulverization is small in particle size and are mixed and granulated with auxiliary materials to obtain the granules. Compared with existing spray drying granulation, the blood enrichment nutri-gel granules have good taste, are easy to absorb and quick to take effect, enriches and nourishes blood, nourishes the liver and kidney, and are used for treating leukopenia and fatigue, weak waist and knees, dizziness, tinnitus, palpitations, breathe hard, insomnia, throat dryness, poor diet and other symptoms caused by radiotherapy and chemotherapy of malignant tumors.

Description

technical field [0001] The invention relates to the technical field of blood-boosting preparations, in particular to an easily absorbed Shengxuebao granule and a preparation method thereof. Background technique [0002] The two Shengxuebao granules currently on the market are produced by Hunan Zhongda Qima Pharmaceutical Co., Ltd. and Hunan Kangshou Pharmaceutical Co., Ltd. respectively. The main ingredients of Shengxuebao Granules are Radix Polygoni Multiflori, Ligustrum lucidum, Mulberry, Eclipta chinensis, Radix Paeoniae Alba, Radix Astragali, and Gouji. Functions and indications are nourishing the liver and kidney, nourishing qi and blood, and used for leukopenia and mental fatigue caused by malignant tumor radiotherapy and chemotherapy, weak waist and knees, dizziness and tinnitus, palpitations, shortness of breath, insomnia, dry throat, poor appetite and other diseases. [0003] The traditional Chinese medicines in the formula of Shengxuebao all have the function of r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61K36/71A61K9/16A61K47/38A61P7/00A61P35/00A61K35/644
CPCA61K9/1652A61K35/644A61K36/12A61K36/28A61K36/481A61K36/605A61K36/638A61K36/65A61K36/704A61K36/71A61K2236/10A61K2236/15A61K2236/331A61K2236/51A61P7/00A61P35/00A61K2300/00
Inventor 谈发金王志锋
Owner 谈发金
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