Preparation method of polyethylene glycol electrolyte powder

A polyethylene glycol and electrolyte technology, applied in the field of medicine, can solve the problems of different dosages, uncontrollable quality, difficult mixing of polyethylene glycol and electrolytes and even layering, etc. Governance and efficacy

Inactive Publication Date: 2019-05-03
四川健能制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Because the density, particle size, particle size shape, specific surface area, porosity, fluidity, etc. of polyethylene glycol and electrolyte are different, it is difficult to mix polyethylene glycol and electrolyte evenly or the powder particles that have been mixed may be affected by equipment. Vibration

Method used

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  • Preparation method of polyethylene glycol electrolyte powder
  • Preparation method of polyethylene glycol electrolyte powder
  • Preparation method of polyethylene glycol electrolyte powder

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Embodiment Construction

[0017] The following further describes the content of the present invention through specific embodiments, but the content of the present invention is not limited thereby.

[0018] The main instruments used in the preferred embodiment are as follows: air-cooled grinder (FL-350 Jiangsu Guibao Group Company); vortex vibrating screen (ZS-650 Jiangsu Guibao Group Company); V-type mixer (VH-10L Nanjing Qunbang Electric Heating Equipment Co., Ltd.).

[0019] 1. Determination of process route and parameters

[0020] 1. Process route determination

[0021] The dosage form of this product is powder, and the preparation process is relatively simple, without adding any auxiliary materials, just pulverize, mix, and package the raw materials of the three bags of A, B, and C separately.

[0022] There are many raw materials for this product, including potassium chloride, sodium bicarbonate, sodium chloride, sodium sulfate, and polyethylene glycol 4000. The sodium sulfate in the prescription is searc...

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Abstract

The invention provides compound polyethylene glycol electrolyte powder and a preparation method thereof. The compound polyethylene glycol electrolyte powder consists of a bag A, a bag B and a bag C, wherein the bag A contains 1 part of potassium chloride and 2.0-2.5 parts of sodium bicarbonate, the bag B contains 1 part of sodium chloride and 3.5-4.0 parts of sodium sulphate, and the bag C contains 1 part of polyethylene glycol (4000). In the compound polyethylene glycol electrolyte powder provided by the invention, all the components are crushed into fine powder, the particle diameter of granules is very small, the specific surface area is large, all the components are easy to disperse, improvement of the dispersibility of the powder of the components is facilitated, uniform mixing of thecomponents in the powder is facilitated, the treatment effects and the medicine effects of the powder are improved, and accelerating the dissolving speed of the powder is also facilitated.

Description

Technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to a compound polyethylene glycol electrolyte powder and a preparation method thereof. Background technique [0002] The purpose of preoperative bowel preparation is to assist the patient to expel accumulated feces and gas, make the bowel empty, reduce flatulence during the operation, and facilitate the exposure of the surgical field, while avoiding anesthetic drugs to relax the anal sphincter during surgery and cause stool contamination of the operating table. The ideal intestinal preparation medicine needs to meet the requirements of clean intestines and no stools, reduce irritation and damage to the lesions, avoid intestinal wall edema, reduce patient pain, and be easy for patients to accept. The commonly used drugs for cleaning the intestines can be divided into stimulant laxatives, volumetric laxatives, lubricating laxatives and osmotic laxatives according to their mecha...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K33/00A61K33/04A61P1/14A61P1/00A61K31/765
Inventor 王国华王祖焕李朝阳刘萍夏能斌
Owner 四川健能制药有限公司
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