Fruit-flavor concentrated type infantile lung-heat-induced cough and asthma oral solution and preparing method thereof

A concentrated type of technology for lung heat, cough and asthma, which is applied in the field of medicine and can solve problems such as large dosage, poor taste, and children's resistance to taking it

Inactive Publication Date: 2019-07-09
葵花药业集团北京药物研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are dosage forms such as Xiaoerfeirekechuan Oral Liquid and Xiaoerfeirekechuan Granules on the market, but most of these preparations have poor taste, large dosage, children resist taking them, and most of the existing oral solutions have precipitation , quality control is more difficult

Method used

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  • Fruit-flavor concentrated type infantile lung-heat-induced cough and asthma oral solution and preparing method thereof
  • Fruit-flavor concentrated type infantile lung-heat-induced cough and asthma oral solution and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Prescription: 100 parts of ephedra, 200 parts of bitter almond, 800 parts of gypsum, 100 parts of licorice, 334 parts of honeysuckle, 334 parts of forsythia, 334 parts of Anemarrhena, 334 parts of skullcap, 334 parts of Radix Radix, 334 parts of Ophiopogon japonicus, 334 parts of Houttuynia cordata part, 0.5 part of preservative, 0.2 part of sweetener, 0.5 part of mixed fruit essence, and 10 parts of polyvinylpyrrolidone.

[0025] Preparation:

[0026] Take the prescribed amount of gypsum, add 4 to 10 times the amount of water and decoct for 0.5 hours, add the rest of ephedra and other ten flavors, add 5 to 10 times the amount of water to decoct twice, each time for 1 hour, combine the decoction, filter, and concentrate the filtrate When the relative density is 1.10-1.15 (80°C), let it cool down, add ethanol to make the alcohol content reach 75%; ℃) clear paste. Take the concentrated extract, add preservatives and sweeteners, add water to dilute to 800ml, stir for 30 ...

Embodiment 2

[0028] Prescription: 100 parts of ephedra, 200 parts of bitter almond, 800 parts of gypsum, 100 parts of licorice, 334 parts of honeysuckle, 334 parts of forsythia, 334 parts of Anemarrhena, 334 parts of skullcap, 334 parts of Radix Radix, 334 parts of Ophiopogon japonicus, 334 parts of Houttuynia cordata 0.5 part of preservative, 0.2 part of sweetener, 0.5 part of grape flavor, 10 parts of polyvinylpyrrolidone.

[0029] Preparation:

[0030] Take the prescribed amount of gypsum, add 4 to 10 times the amount of water and decoct for 0.5 hours, add the rest of ephedra and other ten flavors, add 5 to 10 times the amount of water to decoct twice, each time for 1 hour, combine the decoction, filter, and concentrate the filtrate When the relative density is 1.10-1.15 (80°C), let it cool down, add ethanol to make the alcohol content reach 75%; ℃) clear paste. Take the concentrated extract, add preservatives and sweeteners, add water to dilute to 800ml, stir for 30 minutes, refriger...

Embodiment 3

[0032] Prescription: 100 parts of ephedra, 200 parts of bitter almond, 800 parts of gypsum, 100 parts of licorice, 334 parts of honeysuckle, 334 parts of forsythia, 334 parts of Anemarrhena, 334 parts of skullcap, 334 parts of Radix Radix, 334 parts of Ophiopogon japonicus, 334 parts of Houttuynia cordata part, 0.5 part of preservative, 0.2 part of sweetener, 0.5 part of peach essence, and 10 parts of polyvinylpyrrolidone.

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a fruit-flavor concentrated type infantile lung-heat-induced cough and asthma oral solution and a preparing method thereof. The oral solution is prepared from 100 parts of herba ephedra, 200 parts of semen armeniacae amarae, 800 parts of gypsum, 100 parts of licorice root, 334 parts of honeysuckle flowers, 334 parts of fructus forsythiae, 334 parts of rhizoma anemarrhenae, 334 parts of scutellaria baicalensis, 334 parts of radix isatidis, 334 parts of radix ophiopogonis, 334 parts of houttuynia cordata, 0.5part of a preservative, 0.2 part of a sweetening agent, 0.5 part of an essence and 10 parts of a stabilizer through the scientific method. By means of the added stabilizer, the problem that precipitates are easily generated after an oral solution is placed for a long time is solved, and the product quality stability is improved; meanwhile, the concentrated type oral solution is low in dosage compared with existing conventional oral solutions; in cooperation of the fruit-flavor essence, the feeling of children on the bitter taste can be remarkably relieved, the compliance of children to the preparation is improved, and therefore the treatment effect is improved.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a fruity concentrated infantile Feire Kechuan oral liquid and a preparation method thereof. Background technique [0002] Infants with lung heat are mostly caused by heat evils invading the lung guards, causing fever, sweating, slight aversion to wind and cold, cough, yellow sputum, or wheezing, and dry mouth. These are common syndrome types in children, especially in infants and young children. The highest rate, the pathogen is a variety of viruses and bacteria, or its co-infection. Its treatment principle is mainly clearing heat and detoxifying, clearing the lung and resolving phlegm. [0003] At present, there are dosage forms such as Xiaoerfeirekechuan Oral Liquid and Xiaoerfeirekechuan Granules on the market, but most of these preparations have poor taste, large dosage, children resist taking them, and most of the existing oral solutions have precipitation , quality cont...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/08A61K47/32A61P11/06A61P11/14A61P31/12A61P31/04A61K33/06
CPCA61K9/0095A61K33/06A61K36/17A61K36/195A61K36/315A61K36/355A61K36/484A61K36/539A61K36/634A61K36/736A61K36/78A61K36/8964A61K36/8968A61K47/32A61K2236/331A61K2236/39A61K2236/51A61K2236/55A61P11/06A61P11/14A61P31/04A61P31/12A61K2300/00
Inventor 潘辉盛守霞曲文华
Owner 葵花药业集团北京药物研究院有限公司
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