Fruit-flavor radix-bupleuri cassia-twig fever relieving oral gel for children and preparation method thereof
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A pediatric antipyretic technology, applied in the field of medicine, can solve problems such as difficult quality control, children's resistance to taking, oral liquid precipitation, etc., to achieve the effect of improving compliance, improving curative effect, and reducing bitterness
Inactive Publication Date: 2020-03-27
葵花药业集团北京药物研究院有限公司
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[0003] Currently, Xiaoer Chaigui Antipyretic Oral Liquid and Xiaoer Chaigui Antipyretic Granules are available in the market, but most of these preparations have poor taste and large doses, children resist taking them, and most of the existing oral solutions have precipitation , quality control is more difficult
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Embodiment 1
[0033] Prescription: 260 parts of bupleurum, 260 parts of kudzu root, 120 parts of skullcap, 90 parts of cicada slough, 90 parts of cassia twig, 90 parts of duckweed, 90 parts of white peony, 15 parts of gel matrix (10 parts of k-carrageenan and 5 parts of agar parts), 5 parts of glycerin, 0.5 parts of potassium sorbate, 0.2 parts of sucralose, 0.5 parts of peach essence, and 5 parts of calcium chloride.
Embodiment 2
[0045] Prescription: 260 parts of bupleurum, 260 parts of kudzu root, 120 parts of skullcap, 90 parts of cicada slough, 90 parts of cassia twig, 90 parts of duckweed, 90 parts of white peony, 15 parts of gel matrix (10 parts of k-carrageenan and 5 parts of agar parts), 5 parts of glycerin, 0.5 parts of potassium sorbate, 0.2 parts of sucralose, 0.5 parts of peach essence, and 5 parts of calcium chloride.
Embodiment 3
[0062] Prescription: 260 parts of bupleurum, 260 parts of kudzu root, 120 parts of skullcap, 90 parts of cicada slough, 90 parts of cassia twig, 90 parts of duckweed, 90 parts of white peony, 15 parts of gel matrix (10 parts of k-carrageenan and 5 parts of agar parts), 5 parts of glycerin, 0.5 parts of potassium sorbate, 0.2 parts of sucralose, 0.5 parts of peach essence, and 5 parts of calcium chloride.
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Abstract
The invention pertains-the technical field of medicines, and specifically relates to fruit-flavor radix-bupleuri cassia-twig fever relieving oral gel for children and a preparation method thereof. Per1000 parts of the fruit-flavor radix-bupleuri cassia-twig fever relieving oral gel for the children is prepared from the following raw materials: 200-320 parts of radix bupleuri, 200-320 parts of kudzuvine roots, 90-150 parts of baical skullcap roots, 70-110 parts of cicada slough, 70-110 parts of cassia twigs, 70-110 parts of common ducksmeat herb, 70-110 parts of white peony, 1-50 parts of a gel substrate, 0.1-10 parts of a humectant, 0.1-10 parts of a preservative, 0.1-10 parts of a sweetener, 0.1-10 parts of an essence, 1- 50 parts of a cross-linking agent, and the balance of water. By adopting the dosage form of gel, the fruit-flavor radix-bupleuri cassia-twig fever relieving oral gel for the children is relatively small in dosage compared with oral liquid, and avoids the problem ofliable precipitate production in oral liquid during long-term storage, so that stability of product quality is improved. In addition, the fruit-flavor radix-bupleuri cassia-twig fever relieving oral gel for the children is similar to liquid preparations in terms of easy-to-take property compared with solid preparations, including tablets and the like; that is to say, being taken by a child, contact area between the gel and oral taste receptors is relatively small, so that bitter taste sensed by the child is obviously reduced, thereby improving compliance of the child to the gel in cooperationwith the fruit-flavor essence so as to have curative effects improved.
Description
technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a fruit-flavored children's chaigui antipyretic oral gel and a preparation method thereof. Background technique [0002] Fever caused by exogenous pathogenic factors in children is a common clinical syndrome type in children. This syndrome often shows fever, head and body pain, runny nose, thirst, red throat, yellowish search, and dry stool. The incidence is high especially in infants and young children. It is a variety of viruses and bacteria, or its co-infection, the treatment is mainly sweating to relieve the exterior, clearing the interior to reduce fever. [0003] Currently, Xiaoer Chaigui Antipyretic Oral Liquid and Xiaoer Chaigui Antipyretic Granules are available in the market, but most of these preparations have poor taste and large doses, children resist taking them, and most of the existing oral solutions have precipitation , quality control is difficult....
Claims
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