Apparatus and method for producing 3-acetyl-1-propanol by continuous hydrogenation of 2-methylfuran

A technology of acetyl n-propanol and methyl furan, which is applied in the chemical industry, can solve the problems of wasting hydrogen, cumbersome intermediate material transfer links, and low industrialization efficiency, and achieve the effects of reducing hydrogen loss, improving efficiency, and saving time

Pending Publication Date: 2019-07-26
山东一诺生物质材料有限公司
View PDF1 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are mainly three kinds of production processes of acetyl n-propanol: two kinds are involved in the handbook of fine organic chemical raw materials and intermediates_[Xu Kexun_Editor-in-Chief]: one is the catalytic hydrogenation method of 2-methylfuran palladium chloride, which reacts The cycle is very long (about 120 hours per batch), and the industrialization efficiency is low; the second is the γ-butyrolactone method, which requires a high reaction temperature (350-390°C), and has high requirements f

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Apparatus and method for producing 3-acetyl-1-propanol by continuous hydrogenation of 2-methylfuran
  • Apparatus and method for producing 3-acetyl-1-propanol by continuous hydrogenation of 2-methylfuran
  • Apparatus and method for producing 3-acetyl-1-propanol by continuous hydrogenation of 2-methylfuran

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0046] Replace the fixed bed reactor and related pipelines with nitrogen and hydrogen for three times respectively, control the reaction temperature of the reactor at 25-30°C, start to flow hydrogen into the reactor, keep the pressure of hydrogen at 0.30MPa, and pass the metering pump at 280kg / h The mixture of 2-methylfuran, solvent and water (the ratio of the three is 4:2:1) is fed from the mixing kettle. After the feed pump is turned on, the discharge valve is opened, and the reaction liquid is pressed through the filter in the kettle. After the filtrate in the gas-liquid separator reaches a certain level, the bottom valve is automatically opened, and the reaction liquid enters the secondary reactor for neutralization, and the neutralized liquid is collected in the receiving tank for subsequent distillation, etc. Operation to obtain a qualified product with a yield of 85.3%. A small amount of unreacted 2-methylfuran, solvent and by-product 2-methyltetrahydrofuran distilled ou...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to the field of chemical industry, in particular to an apparatus and method for producing 3-acetyl-1-propanol by continuous hydrogenation of 2-methylfuran. The method comprises metering a mixture of water, a solvent and 2-methylfuran with a metering pump, feeding the metered mixture and metered hydrogen into a reactor, processing with an atomizer, holding certain temperatureand pressure, carrying out hydrogenation in a fixed bed in the atomized state, discharging the reacted liquid directly into a gas-liquid separator, wherein the discharged liquid is in gas-liquid mixedform, discharging the liquid part from the bottom of the gas-liquid separator after the discharge liquid enters the gas-liquid separator, neutralizing with a secondary reactor, and carrying out subsequent distilling and rectifying; processing hydrogen from the upper portion of the gas-liquid separator through a condenser, further cooling residual liquid in the reacted liquid, reserving in a liquid phase, and feeding non-condensed hydrogen into a hydrogen compressor through a hydrogen return pipe for reuse. The feeding quantity is controlled via the metering pump; the discharging quantity is controlled through a liquid level in the gas-liquid separator; therefore, balance is maintained.

Description

technical field [0001] The invention relates to the field of chemical industry, in particular to equipment and a method for continuously hydrogenating 2-methylfuran to produce acetyl n-propanol. Background technique [0002] Acetyl n-propanol is an important pharmaceutical intermediate, the main intermediate of the anti-AIDS drugs efavirenz and irremin, used in the antimalarial drug chloroquine phosphate, and can also be used in the production of vitamin B1, etc., and is also used for sterilization Intermediates of cyprodinil and cyproconazole [0003] At present, there are mainly three kinds of production processes of acetyl n-propanol: two kinds are involved in the handbook of fine organic chemical raw materials and intermediates_[Xu Kexun_editor-in-chief]: one is the catalytic hydrogenation method of 2-methylfuran palladium chloride, which reacts The cycle is very long (about 120 hours per batch), and the industrialization efficiency is low; the second is the γ-butyrolac...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): B01D3/00B01J8/02C07C45/59C07C49/17
CPCB01D3/009B01J8/02C07C45/59C07C49/17
Inventor 王运生刘占杰李敬强
Owner 山东一诺生物质材料有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap