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Chrysanthemum leaf active extract capable of preventing and treating fever combined with cough and inflammation and its preparation method and application

A technology of extract and chrysanthemum leaf, which is applied in the active extract of chrysanthemum leaf which can prevent and treat fever combined with cough and inflammation and its preparation and application, can solve the problems of waste of resources, environment, pollution, etc., increase the amount of secretion, and the process route is simple , the effect of reducing the number of writhing

Active Publication Date: 2021-11-02
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Chrysanthemum is a traditional bulk Chinese herbal medicine in China. The annual output of dried chrysanthemums in my country is about 15,000 tons. In the process of planting and harvesting, only inflorescences are used. The yield of a large number of leaves is much higher than that of inflorescences, but they are usually treated as production waste and discarded. Cause huge waste of resources and environmental pollution

Method used

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  • Chrysanthemum leaf active extract capable of preventing and treating fever combined with cough and inflammation and its preparation method and application
  • Chrysanthemum leaf active extract capable of preventing and treating fever combined with cough and inflammation and its preparation method and application
  • Chrysanthemum leaf active extract capable of preventing and treating fever combined with cough and inflammation and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] The preparation method of the active extract of chrysanthemum leaves for preventing and treating cold comprises the following steps:

[0042] (1) Take 1Kg of fresh chrysanthemum leaves, dry, pulverize, add 10 times the amount of 95% ethanol, soak, heat and decoct 3 times for 2 hours each time, combine the decoction liquid, filter, and pass the supernatant through a 200-mesh sieve, filter, The filtrate is ready for use;

[0043] (2) Take the filter residue from step (1), add 10 times the amount of pure water, heat and decoct 3 times, 2 hours each time, combine the decoction liquid, filter, pass the supernatant through a 200-mesh sieve, and concentrate the filtrate under reduced pressure to a thick paste concentrate;

[0044] (3) Add 80% ethanol to the concentrate of step (2), stir evenly, filter, redissolve the precipitate in water, add 0.1% montmorillonite, stir evenly, heat at 60°C for 0.5h, filter with suction, and concentrate the filtrate to obtain chrysanthemum le...

Embodiment 2

[0048] The preparation method of the active extract of chrysanthemum leaves for preventing and treating cold comprises the following steps:

[0049] (1) Take 1Kg of fresh chrysanthemum leaves, dry, crush, add 20 times, 15 times, 10 times of 95% ethanol in turn, soak, heat and decoct 3 times, each time for 2 hours, combine the decoction, filter, and supernatant Pass through a 200-mesh sieve, filter, and the filtrate is for subsequent use;

[0050] (2) Take the filter residue of step (1), add 20 times, 15 times, and 10 times of pure water in sequence, heat and decoct 3 times, each time for 2 hours, combine the decoction liquid, filter, the supernatant is passed through a 200-mesh sieve, and the filtrate Concentrate under reduced pressure to a thick paste concentrate;

[0051] (3) Add 80% ethanol to the concentrate of step (2), stir evenly, filter, redissolve the precipitate in water, add 0.2% bentonite, stir evenly, heat at 65°C for 0.5h, filter with suction, and concentrate th...

Embodiment 3

[0055] The preparation method of the active extract of chrysanthemum leaves for preventing and treating cold comprises the following steps:

[0056] (1) Take 1Kg of fresh chrysanthemum leaves, dry, crush, add 10 times, 8 times, and 6 times of 95% ethanol in turn, soak, heat and decoct 3 times, each time for 2 hours, combine the decoction liquid, filter, and supernatant Pass through a 200-mesh sieve, filter, and the filtrate is for subsequent use;

[0057] (2) Take the filter residue from step (1), add 10 times, 8 times, and 6 times of pure water in sequence, heat and decoct 3 times, each time for 2 hours, combine the decoction liquid, filter, pass the supernatant through a 200-mesh sieve, and the filtrate Concentrate under reduced pressure to a thick paste concentrate;

[0058] (3) Add 80% ethanol to the concentrate in step (2), stir evenly, filter, redissolve the precipitate in water, add 0.3% kaolin, stir evenly, heat at 70°C for 1.0h, filter with suction, and concentrate t...

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Abstract

The invention discloses an active extract of chrysanthemum leaf which can prevent and treat colds, and its preparation method and application. The extract has good antipyretic, analgesic, antitussive, expectorant, and anti-inflammatory effects, and can be used to prevent and treat fever, cough, phlegm, and inflammatory reactions caused by colds. The present invention mainly uses waste chrysanthemum leaves produced during the harvesting of medicinal chrysanthemums as raw materials, prepares its active extracts, develops its new uses, realizes turning waste into wealth, and can realize comprehensive utilization of chrysanthemum resources and industrial quality improvement. It has good economic, social, ecological and environmental benefits. The preparation method provided by the invention has a simple process route and a high degree of automation; it can relatively comprehensively retain the active ingredients of polysaccharides, flavonoids and phenolic acids in the chrysanthemum leaf raw materials, and can be used to prepare Chinese patent medicines or Chinese veterinary medicines for preventing and treating colds. It has important application prospects.

Description

technical field [0001] The invention relates to an active extract of chrysanthemum leaves which can prevent and treat colds, a preparation method and application thereof. Background technique [0002] Chrysanthemum is the dry flower head of chrysanthemum (Chrysanthemum morifolium Ramat.), which has the effects of dispersing wind and clearing heat, calming liver and improving eyesight. Toxic embolism. Chrysanthemum has a long history of medicinal and edible use in my country. It was first recorded in "Shen Nong's Materia Medica", and was listed as top grade. Modern research has also confirmed its safety. [0003] Chrysanthemum is a traditional bulk Chinese herbal medicine in China. The annual output of dried chrysanthemums in my country is about 15,000 tons. In the process of planting and harvesting, only inflorescences are used. The yield of a large number of leaves is much higher than that of inflorescences, but they are usually treated as production waste and discarded. C...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61K36/287A61P11/00A61P29/00A61P11/10A61P11/14
CPCA61K36/287A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61P11/00A61P11/10A61P11/14A61P29/00
Inventor 魏丹丹段金廒宿树兰郭盛严辉钱大玮
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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