Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Compound resorcinol liposome and preparation method thereof

A technology of compound resorcinol lipid and resorcinol lipid, applied in the field of beauty, can solve the problems of low solubility in water, unsatisfactory effect, poor light stability, etc., to extend the shelf life, eliminate easy oxidation and discoloration, and improve the storage period Effect

Inactive Publication Date: 2019-11-08
屈威翰
View PDF7 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, phenylethyl resorcinol also has some problems in practical application: 1. Low solubility in water; 2. Poor photostability; 3. Large particles, difficult to penetrate into the skin, etc.
[0003] For this reason, some methods have also appeared in the prior art. By mixing phenylethyl resorcinol in the lipid carrier, resorcinol liposomes are made. This method can solve the problems of low solubility and poor photostability. , but the effect is still not ideal, and it needs to be improved, especially the light stability of phenylethyl resorcinol, which has not been ideal

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A preparation method of compound resorcinol liposome, comprises the following steps:

[0034] A. Weigh the lipid material, emulsifier and light stabilizer according to the proportion of the formula, mix and heat to a molten state to obtain a liquid oil phase;

[0035] B. Weigh phenylethylresorcinol, 4-n-butylresorcinol, 4-hexylresorcinol, nicotinamide, arbutin α, tranexamic acid according to the formula, add the liquid oil phase and obtain Homogeneous system, add water to the homogeneous system and stir evenly, put it into a high-pressure homogenizer with a preheating temperature of 80 degrees Celsius and a pressure of 100 MPa, and add a thickener weighed according to the formula into the homogenizer, Homogenize 5 times, each time for 5-8 minutes, to obtain a high-temperature emulsion;

[0036] C. Cool the high-temperature emulsion to normal temperature, and fill in separate bottles to obtain the product.

Embodiment 2

[0038] A kind of compound resorcinol liposome made by the method described in embodiment 1, is made of the raw material of following mass percent: phenylethyl resorcinol 3%; 4 n-butyl resorcinol 3% %; 4 Hexyl Resorcinol 3%; Niacinamide 1%; Arbutin α 1%; Tranexamic Acid 1%; Benzoylmethane 1%; the balance is water.

Embodiment 3

[0040] A kind of compound resorcinol liposome made by the method described in embodiment 1, is made of the raw material of following mass percent: phenylethyl resorcinol 3%; 4 n-butyl resorcinol 3% %; 4 Hexyl Resorcinol 3%; Nicotinamide 1%; Arbutin α 1%; Tranexamic Acid 1%; Benzoylmethane 1.5%; the balance is water.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the field of beauty, and aims to provide a compound resorcinol liposome with a high utilization rate and good light stability and a preparation method thereof. According to the technical scheme, the compound resorcinol liposome is composed of the following raw materials in percentage by mass: 3% of phenylethyl resorcinol, 3% of 4-butylresorcinol, 3% of 4-hexylresorcinol, 1% of niacinamide, 1% of arbutin alpha, 1% of tranexamic acid, 5-10% of lipid material, 3-4% of an emulsifier, 0.5-2% of a thickener, 1-1.5% of a light stabilizer and the balance of water; and the lipid material is caprylic capric triglycerride, the emulsifier is soybean lecithin, the thickener is magnesium aluminum silicate, and the light stabilizer is dibenzoylmethane. The compound resorcinol liposome has excellent water solubility and high content of active ingredients, is non-toxic and harmless, and has good biocompatibility.

Description

technical field [0001] The invention relates to the cosmetic field, in particular to a compound resorcinol liposome and a preparation method thereof. Background technique [0002] With the improvement of living standards, more and more people have higher requirements for skin care, and fair skin has always been advocated by oriental women. As a whitening agent, phenylethyl resorcinol can effectively reduce the production of melanin, and is currently widely used in cosmetics, skin care products and other beauty products. However, phenylethyl resorcinol also has some problems in practical application: 1. Low solubility in water; 2. Poor photostability; 3. Large particles, difficult to penetrate into the skin, etc. [0003] For this reason, some methods have also appeared in the prior art. By mixing phenylethyl resorcinol in the lipid carrier, resorcinol liposomes are made. This method can solve the problems of low solubility and poor photostability. , but the effect is still...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K8/14A61K8/60A61K8/34A61K8/26A61K8/35A61K8/37A61K8/44A61K8/55A61K8/67A61Q19/00A61Q19/02
CPCA61K8/14A61K8/26A61K8/347A61K8/35A61K8/375A61K8/44A61K8/553A61K8/602A61K8/675A61K2800/48A61K2800/52A61Q19/00A61Q19/02
Inventor 屈威翰
Owner 屈威翰
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com