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Skin-grafting paste and preparation method thereof

A skin ointment and skin grafting technology, applied in skin diseases, ointment delivery, pharmaceutical formulations, etc., can solve the problems of non-protection and promotion of mesenchymal cell differentiation, value-added ability, etc., to reduce economic burden, easy operation, and pain small effect

Inactive Publication Date: 2019-11-12
张占忠
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. The external drugs currently used for surgical dressing change have no effect on protecting and promoting the differentiation and proliferation of mesenchymal cells;

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A skin implant cream, comprising the following raw materials in parts by weight: 7 parts of Tianqi, 10 parts of pangolin, 6 parts of bitter ginger, 8 parts of Chinese yam, and 10 parts of borneol.

[0020] The borneol is natural borneol.

[0021] A method for preparing a skin grafting cream as described above, characterized in that it comprises the following steps: S1 weighing raw materials: weighing the raw materials of the skin grafting cream according to the weight ratio; S2 drug fine powder: placing the raw materials of the skin grafting cream in a pulverized Grinding in the machine, and then inject the pulverized raw materials into the grinder for grinding into powder, and the powdered skin grafting paste raw material has a mesh size of 80 mesh; S3 sieving: filter the powdered skin grafting paste raw material, which is mixed with impurities; S4 mixing: put the powder raw materials in a sterilized blender, then add oil and stir evenly to obtain the finished product;...

Embodiment 2

[0024] A skin implant cream, comprising the following raw materials in parts by weight: 13 parts of Tianqi, 12 parts of pangolin, 9 parts of bitter ginger, 12 parts of Chinese yam, and 13 parts of borneol.

[0025] The borneol is natural borneol.

[0026] A method for preparing a skin grafting cream as described above, characterized in that it comprises the following steps: S1 weighing raw materials: weighing the raw materials of the skin grafting cream according to the weight ratio; S2 drug fine powder: placing the raw materials of the skin grafting cream in a pulverized Grinding in the machine, and then inject the pulverized raw materials into the grinder for grinding into powder, and the powdered skin grafting paste raw material has a mesh size of 90 mesh; S3 sieving: filter the powdered skin grafting paste raw material, which is mixed with impurities; S4 mixing: put the powder raw materials in a sterilized blender, then add oil and stir evenly to obtain the finished produc...

Embodiment 3

[0029] A skin implant cream, comprising the following raw materials in parts by weight: 19 parts of Tianqi, 15 parts of pangolin, 13 parts of bitter ginger, 19 parts of Chinese yam, and 15 parts of borneol.

[0030] As a further solution of the present invention: the borneol is natural borneol.

[0031] A method for preparing a skin grafting cream as described above, characterized in that it comprises the following steps: S1 weighing raw materials: weighing the raw materials of the skin grafting cream according to the weight ratio; S2 drug fine powder: placing the raw materials of the skin grafting cream in a pulverized Grinding in the machine, and then inject the pulverized raw materials into the grinder for grinding into powder, and the powdered skin grafting paste raw material has a mesh size of 100 mesh; S3 sieving: filter the powdery skin grafting paste raw material, which is mixed with impurities; S4 mixing: put the powder raw materials in a sterilized blender, then add ...

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PUM

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Abstract

The invention discloses a skin-grafting paste, which includes the following raw materials in parts by weight: 77-30 parts of pseudo-ginseng, 10-20 parts of pangolin, 6-20 parts of bitter galangal, 8-30 parts of dioscorea rhizome, and 10-20 parts of borneol, The preparation method includes: S1 weighing raw materials: weighing the raw materials of the skin-grafting paste in proportion by weight; S2obtaining medicine fine powder; S3 sieving; S4 mixing; S5 putting the finished skin-grafting paste into a sterilized bottle and performing sealing treatment . The skin-grafting paste prepared by the present invention is in close contact with the necrotic skin, penetrates the skin, removes rot, and decomposes the necrotic skin into a honeycomb shape, so that the leather-like necrotic tissue is automatically separated, the pain of necrotic tissue can be dissipated without a surgical excision operation, a necrotic skin layer can be eliminated without damage by liquefied pus-expelling, and the viable residual tissue and potential regenerative cells are preserved.

Description

technical field [0001] The invention relates to the technical field of preparation of skin grafting medicines, in particular to a skin grafting paste and a preparation method thereof. Background technique [0002] Modern surgery mainly uses anti-infection therapy in the treatment of large areas of skin necrosis, skin defects and third-degree burns. The way of traditional therapy is, regardless of how deep the burn wound is, use silver sulfadiazine for external use, and then adopt incision, scab removal and skin grafting to the deep wound. [0003] Dry exposure therapy was practiced before the advent of antibiotics. After antibiotics are available, no matter how large the area of ​​necrosis is or how deep the wound is, antibiotics should be used to control wound infection. For full-thickness skin necrosis and third-degree burns, escharectomy and skin grafting are all used, but another problem in escharectomy is that the necrotic wound is artificially turned into a "knife wo...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K9/06A61P17/02A61K35/36A61K31/045
CPCA61K9/06A61K31/045A61K35/36A61K36/23A61K36/258A61K36/8945A61P17/02A61K2300/00
Inventor 张占忠
Owner 张占忠
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