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A traditional Chinese medicine perfusate for treating female animal endometritis and preparation method thereof

A technology for endometritis and perfusate, which is used in pharmaceutical formulations, medical preparations containing active ingredients, and drug delivery, etc., can solve problems such as harming human health, animal product residues, and reducing reproductive performance of female animals, so as to reduce toxicity. Side effects, solving drug delivery difficulties, and the effect of high drug bioavailability

Active Publication Date: 2021-09-03
ANHUI MUCHUNTANG NATURAL MEDICINE RES DEV CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, the prevention and treatment of endometritis is mainly based on antibacterial drugs and hormones. Although the curative effect is significant, the use of large doses will reduce the reproductive performance of female animals, and will also remain in animal products, endangering human health.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1: a kind of traditional Chinese medicine perfusate and preparation method thereof for the treatment of female animal endometritis, comprises the following steps:

[0026] a. Take 95g of purslane, wash it, add water to squeeze the juice, filter out the medicinal residues, add hydrochloric acid to the filtrate to adjust the pH value to 3.2, heat to boil and then cool, refrigerate at 4°C for 12 hours, filter, add sodium hydroxide to the filtrate to adjust the pH value To 6.5, standby;

[0027] b. Take 35g of Rehmannia glutinosa, 32g of Guiwei, 45g of Achyranthes bidentata, 25g of Cortex Moutan, and 30g of Corydalis Corydalis, and crush them into particles with a particle size of 5.0mm, put them into a Chinese medicine extraction tank, take 15g of Puhuang, put them in a cotton bag and seal them, and put them in In the traditional Chinese medicine extraction tank, add water to soak until the medicinal materials are completely soaked, add ethanol until the alcohol...

Embodiment 2

[0029] Embodiment 2: a kind of traditional Chinese medicine perfusate and preparation method thereof for the treatment of female animal endometritis, comprises the following steps:

[0030] a. Take 100g of purslane, wash it, add water to squeeze the juice, filter out the medicinal residues, add hydrochloric acid to the filtrate to adjust the pH value to 3.5, heat to boil and then cool, refrigerate at 8°C for 12 hours, filter, add sodium hydroxide to the filtrate to adjust the pH value To 7.0, standby;

[0031] b. Take 38g of Rehmannia glutinosa, 30g of Guiwei, 40g of Achyranthes bidentata, 22g of cortex moutan, and 26g of Corydalis cortex, and crush them into particles with a particle size of 3.0mm, put them into a Chinese medicine extraction tank, put 18g of Puhuang into a cotton bag, seal it, and put it into it In the traditional Chinese medicine extraction tank, add water to soak until the medicinal materials are completely soaked, add ethanol until the alcohol content is 7...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine perfusate for treating female endometritis and a preparation method thereof. The traditional Chinese medicine composition of the invention is composed of purslane, rehmannia glutinosa, Guiwei, achyranthes bidentata, Pollen Pollen, Cortex Moutan and Corydalis Corydalis, and auxiliary materials include pH regulator, osmotic pressure regulator and preservative. The composition of the drug in the raw material of the present invention is formed through systematic compatibility research, and has obvious and outstanding synergistic effects. The preparation method thereof can significantly improve the activity of the drug, reduce toxic and side effects, have high bioavailability of the drug, and facilitate clinical administration, etc. .

Description

[0001] (1) Technical field [0002] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine perfusate for treating endometritis in female animals and a preparation method thereof. [0003] (2) Background technology [0004] Female animal endometritis is a common disease and one of the important causes of female infertility. It occurs frequently in cattle, horses and pigs. Due to the influence of various factors such as uterine inflammation and bacterial toxins, lesions appear in the reproductive system and the sexual cycle is disordered, resulting in reduced sperm motility, difficult implantation of fertilized eggs, and repeated infertility. If the disease cannot be treated in time, it will seriously affect the production performance of female animals and bring serious economic losses to breeding farms. The incidence of female endometritis is very high, and it is very harmful to dairy farms and large-scale ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61K9/08A61P15/00
CPCA61K9/0034A61K9/08A61K36/185A61K36/21A61K36/232A61K36/65A61K36/66A61K36/71A61K36/804A61K36/88A61K2236/31A61K2236/331A61K2236/333A61K2236/39A61P15/00A61K2300/00
Inventor 陆凤琪陈文成
Owner ANHUI MUCHUNTANG NATURAL MEDICINE RES DEV CO LTD
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