The invention discloses a preparation method of a traditional Chinese medicine tablet for treating osteoporosis. The preparation method comprises the following steps of: milling radix clematidis, fructus psoraleae, eucommia ulmoides, dipsacus root, medlar, rhizoma anemarrhenae, achyranthes aspera, herba cistanche, oyster, Chinese angelica, cuscuta chinensis, asarum, caulis spatholobi, frankincense, fructus cnidii, and herba lycopi into 40-60-mesh fine powder, adding ethanol, the volume is 3-5 times that of the fine powder, for reflux extraction for 1-2 hours, filtering the resulting product, recycling the ethanol, concentrating the filtrate to thin cream, adding water into the decoction dreg for further decoction, concentrating the filtrated filtrate into thin cream, mixing the thin creams from the two times of concentration, concentrating the mixed thin cream to the thick cream at the density of 1.25-1.35, drying the thick cream to obtain a powder, adding 20-40 parts of starch, 15-25 parts of microcrystalline cellulose, 10-15 parts of hydroxy propyl cellulose, and 10-15 parts of mannitol into the obtained powder for uniform mixing, preparing the resulting mixture to a soft product by using proper 40-60% of ethanol, granulating the soft product by using a 18-20-mesh screen, drying the granulated product at 50-60 DEG C, straightening-granulating the dried product using a 16-18-mesh screen, adding 8-12 parts of hydroxy propyl cellulose, proper silicon dioxide, and proper magnesium stearate into the granulated product for uniform mixing, pressing the mixture for tabletting, and sugar-coating the tablet to obtain the traditional Chinese medicine tablet for treating the osteoporosis. The traditional Chinese medicine tablet has the efficacies of nourishing liver and kidney, tonifying essence and blood, consolidating the kidney and supplementing essence, and can be used for treating the osteoporosis.