SNP locus relevant with spleen weight on chromosome 6 of meat Simmental cattle and application of SNP locus
A Simmental cattle, chromosome technology, applied in recombinant DNA technology, microbial determination/inspection, DNA/RNA fragments, etc., can solve the problems of restricting the application of molecular markers of complex traits, large confidence regions, etc., to increase market competitiveness , Improve the effect of spleen weight
Active Publication Date: 2020-02-07
INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI
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Problems solved by technology
Although the candidate gene method has the advantages of simple method and convenient operation, it can only target genes with known biological functions; while the confidence region of the candidate gene identified by the QTL mapping method is also large, which greatly limits the ability of complex trait molecules Application of markers in livestock genetics and breeding
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Embodiment 1
[0021] 1. Experimental animals
[0022] The experimental cattle groups used in the present invention all come from 1093 Chinese meat-use Simmental cattle in the Uragai management area of Xilin Gol League, Inner Mongolia. Cattle resource groups.
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Abstract
The invention provides an SNP locus relevant with spleen weight on the chromosome 6 of meat Simmental cattle and application of the SNP locus. The SNP marker locus is the 38852378th nucleotide locus on the chromosome 6 of UMD3.1 version of national cattle reference genome assembly, and the base of the locus is G or A. By optimizing the preferential alleles of the SNP, the frequency of the preferential alleles can be increased generation by generation, the spleen weight of the meat Simmental cattle is increased, and a genetic improvement progress of the Simmental cattle can be accelerated, so that the economic benefits of breeding beef cattle are effectively increased.
Description
technical field [0001] The invention relates to a SNP site on chromosome 6 of meat Simmental cattle related to spleen weight and its application. Background technique [0002] Meat Simmental is the most popular breed of cattle hybrids in China. It has the characteristics of fast growth and high meat production rate, so it is often used as the terminal male parent in breeding production. Bovine spleen, commonly used in Chinese medicine in China, has the effect of invigorating the spleen and appetizing, eliminating accumulation and swelling. At present, the breeding of Simmental cattle for meat mainly focuses on improving growth traits such as meat yield and growth speed, while less attention is paid to the selection and breeding of spleen weight. In addition, spleen weight is a quantitative trait controlled by multiple genes, and there are a large number of quantitative trait loci (quantitative trait loci, QTLs) related to it on the genome. Therefore, it is difficult to rap...
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IPC IPC(8): C12Q1/6888C12N15/11
CPCC12Q1/6888C12Q2600/124C12Q2600/156C12Q2600/172
Inventor 刘影朱波李俊雅徐玲庄站伟徐凌洋张路培高会江高雪陈燕蔡文涛
Owner INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI
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