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Antibacterial medical dressing capable of promoting rapid healing of wounds and preparation method thereof

An antibacterial and wound technology, applied in medical science, bandages, etc., to achieve definite curative effect, prevent wound infection, and broad practical application value

Inactive Publication Date: 2020-05-05
WENZHOU MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But few medical dressings can achieve the effect of not only controlling infection but also helping cell proliferation and promoting wound healing

Method used

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  • Antibacterial medical dressing capable of promoting rapid healing of wounds and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] An antibacterial medical dressing for promoting rapid wound healing, comprising the following raw material components in percentage by weight: 0.2% of vascular endothelial growth factor, 2% of silk fibroin aqueous solution, 2.5% of sodium alginate, 2% of sodium hyaluronate, and 3% of levofloxacin %, polyethylene glycol 400-20%, carbomer 8%, and the balance is deionized water.

[0023] Among them, vascular endothelial growth factor was purchased from Sigma Company of the United States; silk fibroin was purchased from Xi'an Four Seasons Biotechnology Co., Ltd. (molecular weight is 5000-10000, content is 98%); ; Other products and reagents are conventional commercially available.

[0024] The preparation method of the antibacterial medical dressing for promoting rapid wound healing comprises the following steps: mixing vascular endothelial growth factor, silk fibroin aqueous solution, sodium alginate, sodium hyaluronate, polyethylene glycol 400, carboxy Boomer and an appr...

Embodiment 2

[0026] An antibacterial medical dressing for promoting rapid wound healing, comprising the following raw material components in percentage by weight: vascular endothelial growth factor 0.5%, silk fibroin aqueous solution 1.8%, calcium alginate 2.8%, sodium hyaluronate 4%, Qingda Mycin 2.5%, polyethylene glycol 600-25%, carbomer 6%, and the balance is deionized water.

[0027] The preparation method of the antibacterial medical dressing for promoting rapid wound healing is the same as in Example 1.

Embodiment 3

[0029] An antibacterial medical dressing for promoting rapid wound healing, comprising the following raw material components in percentage by weight: vascular endothelial growth factor 0.4%, silk fibroin aqueous solution 1.6%, zinc alginate 3%, sodium hyaluronate 3%, molybdenum hydrochloride Cifloxacin 2%, polyethylene glycol 800 26%, carbomer 7%, and the balance is deionized water.

[0030] The preparation method of the antibacterial medical dressing for promoting rapid wound healing is the same as in Example 1.

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Abstract

The invention belongs to the field of medical dressings, and specifically relates to an antibacterial medical dressing capable of promoting the rapid healing of wounds and a preparation method thereof. The medical dressing can cooperatively use various active components such as vascular endothelial growth factors, silk fibroin, alginate and antibacterial drugs, so that long-acting bacteriostasis can be realized, and wound infection can be prevented; and the medical dressing has synergistic effects on promoting the rapid growing of the granulation tissue of the wounds, so that the purpose of the rapid healing of the wounds can be achieved, and no recurrence occurs after treatment.

Description

technical field [0001] The invention belongs to the field of medical dressings, and in particular relates to an antibacterial medical dressing for promoting rapid wound healing and a preparation method thereof. Background technique [0002] Wounds can be defined as skin defects caused by mechanical, electrical, thermal, chemical and other factors or due to physiological abnormalities. Clinically, poor wound healing includes wound edge necrosis, skin necrosis, skin erosion, incision dehiscence, fat liquefaction, sinus tract formation, hematoma formation, etc. The incidence of these complications is 2-37%. Wound non-healing not only brings great pain to patients, but also takes up a lot of medical resources. For some difficult-to-heal wounds, ordinary bandaging treatment is often difficult to heal, and special means are required. The reasons for difficult wound healing include damage to human immune cells caused by certain systemic diseases; insufficient cell regeneration ab...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0047A61L26/0023A61L26/0019A61L26/0014A61L2300/232A61L2300/252A61L2300/404A61L2300/406A61L2300/412A61L2300/414C08L5/04C08L5/08C08L71/02C08L33/02
Inventor 张宏宇肖健许可孔晓霞
Owner WENZHOU MEDICAL UNIV
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