Compositions and methods for treating conditions associated with altered tca cycle metabolism

A compound and intermediate technology, applied in the field of pathological compositions, to achieve the effect of easy absorption and high solubility

Pending Publication Date: 2020-05-26
IMBRIA PHARMA INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing compositions are insufficient to remedy TCA cycle dysfunction, and humans continue to suffer from and die from a variety of pathologies associated with abnormal TCA cycle metabolism

Method used

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  • Compositions and methods for treating conditions associated with altered tca cycle metabolism
  • Compositions and methods for treating conditions associated with altered tca cycle metabolism
  • Compositions and methods for treating conditions associated with altered tca cycle metabolism

Examples

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example 1

[0141] Example 1: Preparation and analysis of compounds of formula (XIII). The compound of formula (XIII) was found to have a solubility in water of 1.2 g / mL and taste slightly sweet but not too bitter.

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Abstract

Compositions and methods for treating conditions associated with altered TCA cycle metabolism are provided.

Description

[0001] Cross References to Related Applications [0002] This application claims U.S. Provisional Patent Application No. 62 / 677,940, filed May 30, 2018, U.S. Provisional Patent Application No. 62 / 667,893, filed May 7, 2018, filed April 24, 2018 U.S. Provisional Patent Application No. 62 / 662,014, filed March 30, 2018 U.S. Provisional Patent Application No. 62 / 650,395, filed February 16, 2018 U.S. Provisional Patent Application No. 62 / 710,357, filed February 16, 2018, filed 2017 Benefit and priority of U.S. Provisional Patent Application No. 62 / 547,547, filed August 18, 2017, and U.S. Provisional Patent Application No. 62 / 536,318, filed July 24, 2017, each of these U.S. Provisional Patent Applications The contents of the US Provisional Patent Application are incorporated by reference. technical field [0003] The present application relates to compositions and methods for treating conditions associated with altered TCA cycle metabolism. Background technique [0004] Abnorma...

Claims

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Application Information

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IPC IPC(8): A61K31/225C07C69/40
CPCC07C69/40C07C229/22C07C229/36A61K31/225C07C321/04A61K31/00A61K31/198
Inventor A·莱文
Owner IMBRIA PHARMA INC
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