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Method of animating transitions and stabilizing node motion during dynamic graph navigation

In a system and method for arranging a graph according to a Force-Directed Layout algorithm, a node-set transition in the graph may be animated by iteratively reducing or increasing an impact value of one node on another node, and a velocity of a node may be reduced in proportion the to the degree of its non-directional movement.
Owner:TOUCHGRAPH

System and method for labeling pharmaceutical prescriptions

InactiveUS20050038558A1Reduce riskQuickly and easily recognize important informationStampsDrug and medicationsFood supplementCombined use
The present invention provides a system and method for labeling pharmaceutical prescriptions. In accordance with various embodiments of the present invention, a label module compiles data and creates a customized medication label system for each medication or food supplement for a patient which is easy to understand due to the use of graphical representations of the medication or food supplement. The label system may further provide pictograms describing directions for use. A corresponding schedule may be generated will when used in conjunction with the label system reduces the possibility of mis-medication.
Owner:KEENE ASTRID I S

Route guidance assistance by moment support at the steering wheel

A device and a method for route guidance assistance in a vehicle that is connected to a navigation system. In order to make it easier for the driver to follow a route calculated by a navigation system, an assisting device is provided for route guidance. The assisting device includes a control unit for generating a control signal for haptic feedback to the driver of the vehicle. As haptic feedback, the control unit can output an additional moment on the steering system of the vehicle, for example, the additional moment being negative when the vehicle departs from the travel route while being positive when the vehicle follows the calculated direction of the navigation route.
Owner:CONTINENTAL TEVES AG & CO OHG

Intelligent luggage barrow of airport

The invention discloses an intelligent luggage barrow of an airport. The intelligent luggage barrow is characterized in comprising a main body frame, a control panel, a deep visual identification device, a control box and a chassis driving device, wherein the main body frame comprises a luggage load bearing device and a functional frame; the functional frame comprises two supporting rods and an advertising space panel arranged between the two supporting rods; a small part luggage frame is arranged between the supporting rods on the top; two sides of the top end of each supporting rod are provided with panel supporting frames; the control panel is embedded into the panel supporting frames on two sides and is fixed by bolts; the deep visual identification device is fixed on a rear plate of the small part luggage frame; the chassis driving device is arranged on a wheel axle, and the supporting rods above the chassis driving device are riveted with the control box; a control system is integrated in the control box. According to the intelligent luggage barrow, functions including autonomous navigation, intelligent following, voice interaction, service consultation, on-line entertainment, convenient shopping, automatic weighting, forbidden article detection, automatic conversation, one-key recovery, kid missing prevention, automatic printing of boarding checks and the like are combined, and the intelligent luggage barrow of the airport can lead intelligent, fashionable, relaxed and convenient brand-new airport service experience.
Owner:四川西部动力机器人科技有限公司

Insertion of medical devices through non-orthogonal and orthogonal trajectories within the cranium and methods of using

The invention comprises an elongated device adapted for insertion, including self-insertion, through the body, especially the skull. The device has at least one effector or sensor and is configured to permit implantation of multiple functional components through a single entry site into the skull by directing the components at different angles. The device may be used to provide electrical, magnetic, and other stimulation therapy to a patient's brain. The lengths of the effectors, sensors, and other components may completely traverse skull thickness (at a diagonal angle) to barely protrude through to the brain's cortex. The components may directly contact the brain's cortex, but from there their signals can be directed to targets deeper within the brain. Effector lengths are directly proportional to their battery size and ability to store charge. Therefore, longer angled electrode effectors not limited by skull thickness permit longer-lasting batteries which expand treatment options.
Owner:HUA SHERWIN

Dimer of molecular variant of apolipoprotein and processes for the production thereof

Substantially pure dimers of Apolipoprotein AI-Milano (APO-AI-M / APO AI-M) were isolated from plasma and characterized. Apolipoprotein AI-M dimer can also be produced in a recombinant Escherichia coli system. Pharmaceutical compositions comprising the ApoAI-AI-M / ApoAI-M are described. Patients with atherosclerosis or cardiovascular diseases can be treated with the dimer. Medicaments containing the dimer can also be used to prevent thrombosis in different clinical circumstances, both at the arterial and at the venous level. The dimer can also act as a prodrug for the monomer.
Owner:PFIZER INC

Method and system for creating and following drill links

InactiveUS20050034064A1Efficiently and inexpensively provideEasy to followRelational databasesSpecial data processing applicationsData storeDrill
A method and system for creating and following drill links in a report are disclosed. A relational abstraction of a data store is defined, the definition including a plurality of views, scalar or aggregate fields associated with the views, and relations between the views. A report is generated that includes at least one drill link associated with a sequence of one or more relations originating at a base view of the relational abstraction. Upon selecting a drill link contained in a first report, information about the drill link is extracted from the report, and the extracted information and the destination view associated with the drill link are used to create a second report.
Owner:MICROSOFT TECH LICENSING LLC

Methods of treating cancer with HDAC inhibitors

The present invention provides methods of treating cancers, chemoprevention, selectively inducing terminal differentiation, cell growth arrest and / or apoptosis of neoplastic cells, and / or inhibiting histone deacetylase (HDAC) by administration of pharmaceutical compositions comprising potent HDAC inhibitors. The oral bioavailability of the active compounds in the pharmaceutical compositions of the present invention is surprisingly high. Moreover, the pharmaceutical compositions unexpectedly give rise to high, therapeutically effective blood levels of the active compounds over an extended period of time. The present invention further provides a safe, daily dosing regimen of these pharmaceutical compositions, which is easy to follow, and which results in a therapeutically effective amount of the HDAC inhibitors in vivo.
Owner:MERCK HDAC RESEARCH LLC +1

Methods of treating cancer with hdac inhibitors

InactiveUS20070060614A1Better pharmacokinetic profileImprove bioavailabilityBiocideAnimal repellantsDosing regimenOncology
The present invention relates to methods of treating cancers, e.g., mesothelioma or lymphoma. More specifically, the present invention relates to methods of treating mesothelioma or diffuse large B-cell lymphoma (DLBCL), by administration of pharmaceutical compositions comprising HDAC inhibitors, e.g., suberoylanilide hydroxamic acid (SAHA). The oral formulations of the pharmaceutical compositions have favorable pharmacokinetic profiles such as high bioavailability and surprisingly give rise to high blood levels of the active compounds over an extended period of time. The present invention further provides a safe, daily dosing regimen of these pharmaceutical compositions, which is easy to follow, and which results in a therapeutically effective amount of the HDAC inhibitors in vivo.
Owner:MERCK HDAC RESEARCH LLC +1

Wipe material with nanofiber layer

A flexible wipe comprising at least one conformable non-woven layer and at least one adhered nanofiber layer can be used to remove a variety of particulate soils from planar, curved or complex surfaces. The nanofiber layer is configured onto the flexible non-woven in a fashion such that particulate of a broad particle size range is trapped by the nanofiber layer and efficiently removed from the contaminated surface. The nanofiber layer comprises a web of spun fibers that can incorporate and trap soil particles for efficient soil removal.
Owner:DONALDSON CO INC

Structural element for a shoe sole

The present invention relates to a shoe sole including a cushioning element. The shoe sole can include a heel cup or heel rim having a shape that substantially corresponds to the shape of heel of a foot. Further, the heel part can include a plurality of side walls arranged below the heel cup or rim and at least one tension element that interconnects at least one side wall to another side wall or to the heel cup or rim. The heel cup or rim, the plurality of side walls, and the at least one tension element can be integrally formed as a single piece.
Owner:ADIDAS

Systems and methods for deploying echogenic components in ultrasonic imaging fields

Systems and devices according to the present invention providing a needle deployment and visualization device, which includes: a shaft; an ultrasound imaging transducer extendable along at least a portion of the shaft for providing an image within a field of view; and a needle coupled and deployable from the shaft within the field of view. The needle has an artifact configured to preferentially reflect at least a portion of the ultrasound energy emanating from the ultrasound transducer back to the transducer in order to enhance imaging of the needle.
Owner:GYNESONICS

Displaying links at varying levels of prominence to reveal emergent paths based on user interaction

Links in a system may be displayed at varying prominence based on user interaction with the links. Link paths chosen by users become apparent by virtue of display prominence of the links. A link may be displayed with greater or lesser prominence corresponding to the propensity of users to interact with the link. Prominence values that affect a prominence at which links are displayed may be modified based on user interaction information. Prominence values may further automatically decay, possibly over time or according to user interaction with the links. Using and modifying prominence values in this manner, links that emerge with greater prominence may form one or more “paths” that users can readily follow. Much as in the natural world where pheromones deposited by ants attract other ants to desirable paths, user interaction information can be advantageously used to automatically identify more desirable link paths to a resource.
Owner:AMAZON TECH INC

Structural element for a shoe sole

The present invention relates to a shoe sole including a cushioning element. The shoe sole can include a heel cup or heel rim having a shape that substantially corresponds to the shape of heel of a foot. Further, the heel part can include a plurality of side walls arranged below the heel cup or rim and at least one tension element that interconnects at least one side wall to another side wall or to the heel cup or rim. The heel cup or rim, the plurality of side walls, and the at least one tension element can be integrally formed as a single piece.
Owner:ADIDAS

Method and device for sensing walking gait of strength enhanced power exoskeleton

InactiveCN103431929AImprove real-time performanceImprove carrying speedArtificial legsGyroscopeKnee Joint
The invention relates to a method for sensing the walking gait of a strength enhanced power exoskeleton and a sensing measuring device. The method particularly includes the specific steps that a sole pressure sensor, a knee joint encoder and a gyroscope are utilized to measure person ground touch information, joint angle change information and thigh and shank angular speed information, a method for partitioning the walking gait to five sub phases is provided according to a man-machine accompanying rule, wherein the five sub phases relates to both leg standing, left leg supporting and right leg swing, both leg supporting and right leg forward, right leg supporting and left leg swing, both leg supporting and left leg forward and the like, classification decision is conducted on the measuring information in the five gait sub phases by the adoption of a machine learning C4.5 algorithm, and then an identification method in which data are combined with the walking gait sub phases is provided. The method and the device have the advantages that walking gait classification decision is achieved by utilizing the limited measuring information on the exoskeleton, the provided man-machine accompanying gait identification method can improve real-time performance of the exoskeleton for following limb motion of a person who tries on the exoskeleton, a hydraulic control system can shrink in advance, and man-machine accompanying speed is increased.
Owner:成都奥特为科技有限公司

Parking lot attendant robot system

A parking lot attendant robot is provided with a camera for capturing an image of an vehicle and a parking space, and a receiver from receiving vehicle information such as the steering angle, shift position and vehicle speed from the vehicle. Based on the knowledge of the position of the vehicle with respect to the parking space gained from the camera and the vehicle information received from the vehicle, the robot computes the optimum parking path which the vehicle should follow. The robot signals the motorist by a visual and / or auditory display and / or a hand signal as to how the steering wheel should be turned and which way the vehicle should move or stop for the vehicle to follow this parking path and to be successfully parked in the prescribed parking space.
Owner:HONDA MOTOR CO LTD

A System and Method for transferring a website from one web host to another

The current invention is designed to simplify the process it takes to transfer a website from one web host to another. The system will transfer a user's information through a series of easy to follow screens, similar to a Microsoft Windows wizard. The system will support the transfer of all HTML files and scripts form all of the major hosting panels such as Cpanel, Plesk, Vdeck and more, as well as transferring the necessary files, it will also allow users to create up to five E-mail accounts during the session. In addition, the system will support the importing ability of control panel exports form all of the major control panels. This will allow the system 1 to move the necessary files over, as well as E-mail addresses and database content.
Owner:NEUMAN BEN

Method and system for recovering the energy state of an aircraft during descent

A method and system is provided for the recovery of an aircraft energy upset in a time-constrained descent. The system includes a computational unit to assess a number of adjustments involving a combination of speed changes, aerodynamic brake deployment and track miles adjustments that alter the energy dissipation profile whilst allowing the aircraft to maintain a pre-determined time-of-arrival over an incoming waypoint along the original descent path.
Owner:UNIVERSITY OF MALTA

Methods of treating cancer with HDAC inhibitors

The present invention provides methods of treating cancers, chemoprevention, selectively inducing terminal differentiation, cell growth arrest and / or apoptosis of neoplastic cells, and / or inhibiting histone deacetylase (HDAC) by administration of pharmaceutical compositions comprising potent HDAC inhibitors. The oral bioavailability of the active compounds in the pharmaceutical compositions of the present invention is surprisingly high. Moreover, the pharmaceutical compositions unexpectedly give rise to high, therapeutically effective blood levels of the active compounds over an extended period of time. The present invention further provides a safe, daily dosing regimen of these pharmaceutical compositions, which is easy to follow, and which results in a therapeutically effective amount of the HDAC inhibitors in vivo.
Owner:BACOPOULOS NICHOLAS G +4

Method for realizing mobile terminal dynamic cache memory multimedia interactive advertisement

The invention provides a method to realize multimedia interactive advertisement of the mobile terminal dynamic caching, which sets the ad table and only ID code of each ad on the netserver, the corresponding ID code on the mobile terminal, memory and procedure on the gateway. When mobile users access wireless Internet, multimedia document of ad is pushed to the mobile terminal and stored into the special catalog. The multimedia document contains the counter of cycle number, the information of advertising validity, and at the end of document. The interactive interface has the additional information options of advertiser. The advantages of the invention are that the method does not to disturb the communication and surfing on Internet of user, and can improve the effect of ad to achieve the data statistics of publishing ad.
Owner:韩壮

Histone Deacetylase Inhibitor Prodrugs

The present invention is directed to prodrugs of hydroxamic acid based histone deacetylase (HDAC) inhibitors, e.g., suberoylanilide hydroxamic acid (SAHA). The prodrugs are acylated derivatives having increased aqueous solubility and cellular permeability as compared with the free hydroxamic acid, and are useful for inhibiting HDACs, and for selectively inducing terminal differentiation, cell growth arrest and / or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the prodrugs of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The prodrugs of the invention are also useful in the prevention and treatment of thioredoxin (TRX)-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and / or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases.
Owner:MERCK HDAC RESEARCH LLC

Methods of treating cancer with HDAC inhibitors

InactiveUS20080249179A1Better pharmacokinetic profileImprove bioavailabilityBiocideOrganic chemistryDosing regimenIn vivo
The present invention relates to methods of treating cancers, e.g., leukemia. More specifically, the present invention relates to methods of treating acute and chronic leukemias including Acute Lymphocytic Leukemia (ALL), Acute Myeloid Leukemia (AML), Chronic Lymphocytic leukemia (CLL), Chronic myeloid leukemia (CML) and Hairy Cell Leukemia, by administration of pharmaceutical compositions comprising HDAC inhibitors, e.g., suberoylanilide hydroxamic acid (SAHA). The oral formulations of the pharmaceutical compositions have favorable pharmacokinetic profiles such as high bioavailability and surprisingly give rise to high blood levels of the active compounds over an extended period of time. The present invention further provides a safe, daily dosing regimen of these pharmaceutical compositions, which is easy to follow, and which results in a therapeutically effective amount of the HDAC inhibitors in vivo.
Owner:MERCK HDAC RESEARCH LLC +1

Method for processing residual sludge with integrated process of alkaline hydrolysis preprocessing, nitrogen and phosphorus recovery based on magnesium ammonium phosphate method and methane production based on anaerobic digestion

ActiveCN103693828AReduce consumptionGive full play to the role of alkaline hydrolysis pretreatmentWaste based fuelSludge processingChemical oxygen demandMagnesium salt
The invention discloses a method for processing residual sludge with an integrated process of alkaline hydrolysis preprocessing, nitrogen and phosphorus recovery based on a magnesium ammonium phosphate method and methane production based on anaerobic digestion. The method comprises the steps of: preprocessing residual sludge with a secondary alkaline hydrolysis method to obtain supernate, adding a magnesium salt solution to separate precipitates, subjecting the supernate to anaerobic processing, and drying the precipitates naturally to obtain crude magnesium ammonium phosphate; injecting the supernate into an anaerobic reactor, and inoculating with 10-60% anaerobic granular sludge, wherein the volumetric loading is controlled to be 0.30-0.75kg COD (Chemical Oxygen Demand) / (m<3>.d), and the productivity of methane reaches 200-400mL CH4 / gCOD within 72h. The method disclosed by the invention has the advantages that nutrition elements in the residual sludge are utilized comprehensively, the process is simple and is consistent in flow with low chemical consumption and electricity consumption, methane is recovered while crude magnesium ammonium phosphate is obtained, moreover, residual alkaline solids are beneficial to subsequent processing, and the reduction, stabilization and recycling of the residual sludge are realized comprehensively.
Owner:SOUTH CHINA UNIV OF TECH

Nutritional dietary system, formulation, kit and method for use in preparing an individual for a predetermined activity

InactiveUS20030180393A1Enough caloriesWithout loss of nutritional benefitBiocideOrganic active ingredientsBiotechnologyReady to eat
This invention relates to a nutritional dietary system, formulation, kit and method for use in preparing an individual for a predetermined activity which requires a clean digestive tract, particularly the colon. Such predetermined activities include, but are not limited to, gastrointestinal surgery and colon screenings. Specifically, the present invention provides an individual low amounts of fat, dietary fiber and solid food content to minimize stool formation and / or facilitate removal of stool from the digestive tract prior to the predetermined activity. The present invention also provides the individual with sufficient calories and nutrition to enable the individual to conduct daily, routine activities while utilizing the present invention. In one alternative embodiment, the dietary regimen of the present invention provides a variety of pre-packaged, ready to eat or easy to prepare nutritional liquid or solid foods which, when coordinated with a laxative regimen, result in removal of residue such that a medically and / or diagnostically useful procedure can be performed on the digestive tract.
Owner:BRACCO DIAGNOSTICS

Parking lot attendant robot system

A parking lot attendant robot is provided with a camera for capturing an image of an vehicle and a parking space, and a receiver from receiving vehicle information such as the steering angle, shift position and vehicle speed from the vehicle. Based on the knowledge of the position of the vehicle with respect to the parking space gained from the camera and the vehicle information received from the vehicle, the robot computes the optimum parking path which the vehicle should follow. The robot signals the motorist by a visual and / or auditory display and / or a hand signal as to how the steering wheel should be turned and which way the vehicle should move or stop for the vehicle to follow this parking path and to be successfully parked in the prescribed parking space.
Owner:HONDA MOTOR CO LTD

Structural element for a shoe sole

The present invention relates to a shoe sole including a cushioning element. The shoe sole can include a heel cup or heel rim having a shape that substantially corresponds to the shape of heel of a foot. Further, the heel part can include a plurality of side walls arranged below the heel cup or rim and at least one tension element that interconnects at least one side wall to another side wall or to the heel cup or rim. The heel cup or rim, the plurality of side walls, and the at least one tension element can be integrally formed as a single piece.
Owner:ADIDAS

Thiophene and Benzothiophene Hydroxamic Acid Derivatives

The present invention relates to a novel class of hydroxamic acid derivatives having a benzothiophene or thiophene backbone. The hydroxamic acid compounds can be used to treat cancer. The hydroxamic acid compounds can also inhibit historic deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and / or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention are also useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and / or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the hydroxamic acid derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the hydroxamic acid derivatives in vivo.
Owner:MERCK HDAC RESEARCH LLC

System, method and apparatus for software generated slide show

A system, method and apparatus for a software generated slide show comprising a personal organizer software programed to correspond to a plurality of individual users. The organizer having a plurality of screens through which each of the users can navigate with each of the screens having a slide show window. A first series of selected pictures can be presented for a preselected time period on each of the screens of the software program. The selected pictures can appear in the slide show window independently of the screen said user is viewing. A calendar provided by the software program can hold personal appointments, events and affairs of each of the users separately.
Owner:VOGEL JEFF
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