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A preparation for controlling ovulation of equine animals and a method for controlling ovulation

A kind of preparation and purpose technology, which is applied in the field of ovulation control preparation and ovulation control of equine animals, can solve the problems that the ovulation control method of mare is difficult to apply to female donkeys, and the international price of donkey skins is soaring, etc., so as to achieve low raw material prices and low production costs , Efficient ovulation control effect

Active Publication Date: 2022-02-08
CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the demand for live donkeys is increasing day by day. The donkey-hide gelatin market alone currently needs 4 million donkey skins per year, while the total stock of donkeys in China is less than 5 million. The supply is in short supply, and we have to rely on foreign imports, resulting in skyrocketing international donkey skin prices.
At present, there are few studies on ovulation control of female donkeys at home and abroad, and the ovulation control methods used for female horses are difficult to apply to female donkeys.

Method used

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  • A preparation for controlling ovulation of equine animals and a method for controlling ovulation
  • A preparation for controlling ovulation of equine animals and a method for controlling ovulation
  • A preparation for controlling ovulation of equine animals and a method for controlling ovulation

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Effect test

Embodiment 1

[0047] The preparation of the ovulation fluid of embodiment 1 control animal ovulation

[0048] 1. Ovulation fluids containing different sustained-release carriers and their application effects

[0049] (1) Preparation of ovulation fluid containing different slow-release carriers

[0050] The following A~J respectively provide the ovulation fluid containing different slow-release carriers in this embodiment:

[0051] A. Weigh 0.1g of deserelin and 2.0g of trehalose, add ethanol to fully dissolve to obtain a gonadotropin-releasing hormone solution; weigh 700g poly(DL-lactide-co-glycolide), add ethanol to fully Dissolve to obtain a slow-release carrier solution; mix the two solutions evenly, make up to 1000 g with ethanol, and obtain 0.01% deserelin ovulation solution.

[0052] B. Weigh 0.1g of deserelin and 2.0g of trehalose, add ultrapure sterile water to fully dissolve to obtain a gonadotropin-releasing hormone solution; weigh 700g of polysucrose, add ultrapure sterile wate...

Embodiment 2

[0098] The ovulation control of embodiment 2 Akhate gold (sweat blood) horse and the effect of natural mating

[0099] Near Hohhot, Inner Mongolia, 32 Ahatekin mares aged 3 to 10 years old were selected, with moderate body condition, healthy and normal fecundity. They were raised in pens with an outdoor playground, had free access to water, and were fed green hay (leymus chinensis and alfalfa) twice. From April to June, test the stallion with the stallion every morning from 8:00 to 10:00. If the stallion stands still after approaching, lifts its tail, opens its vulva frequently, and discharges urine, it means that the mare is ready for breeding. At the same time, use a B-ultrasound probe to check the follicles and uterine edema across the rectal wall. On the B-ultrasound machine, the "cross method" is used to measure the diameter of the follicle, that is, measure a maximum value in the longitudinal direction, then cross vertically, measure a maximum value in the horizontal di...

Embodiment 3

[0102] Example 3 Ovulation control of Mongolian horses and the effect of using frozen semen for breeding

[0103] In the vicinity of Shenyang City, Liaoning, 35 mares of Mongolian horses aged 3 to 8 were selected, with moderate fat condition, healthy and normal fecundity. They were reared in pens with an outdoor sports field, free to drink water, and fed green hay (leymus chinensis and alfalfa) twice. From June to August, from 8:00 to 10:00 in the morning, B-ultrasound rectal examination was used to check the development of follicles in the horse herd. On the B-ultrasound machine, the "cross method" is used to measure the diameter of the follicle, that is, measure a maximum value in the longitudinal direction, then cross vertically, measure a maximum value in the horizontal direction, add the two values ​​and take the average value, which is the diameter of the follicle. When the diameter of the follicle reaches more than 35mm and the edema of the endometrium is obvious, the ...

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Abstract

The invention provides a preparation for controlling ovulation of equine animals and a method for controlling ovulation. The preparation comprises a gonadotropin-releasing hormone analogue and a degradable slow-release carrier in the animal body. By preparing the gonadotropin-releasing hormone as a slow-release preparation, its half-life in the body is effectively prolonged, so that the preparation can play a long-term, efficient and stable role in promoting ovulation. By injecting the preparation of the present invention, more than 96% of mares and donkeys ovulate within 48 hours, and the ovulation time of more than 96% of the animals is controlled within 8 hours, realizing efficient ovulation control of equine animals and significantly improving Breeding pregnancy rates in equines. The ovulation control method of the present invention is easy to operate, low in cost and remarkable in control effect, does not produce any harmful effects on the animal itself and its products, and can be widely used in mating species of equine animals, artificial insemination, embryo transfer and timed insemination, Has broad market prospects.

Description

technical field [0001] The invention relates to the field of animal reproduction, in particular to a preparation for controlling ovulation of equine animals and a method for controlling ovulation. Background technique [0002] With the development of the national economy and the improvement of people's living standards, industries such as horse breeding, training, competition and leisure and entertainment have developed rapidly, and the market potential is huge. In recent years, its output value has shown a linear upward trend. It is estimated that by 2030, China's horse industry The total output value will reach trillions. At present, there are about 6 million horses in stock in China, but the quality is uneven, and there is a lack of special speed, endurance performance, equestrian and leisure riding breeds, which cannot meet the current market demand. Therefore, the breeding of characteristic thoroughbred horses is one of the problems to be solved urgently at present. A...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/09A61K47/36A61K47/34A61K47/10A61K47/26A61P15/08A61D19/02
CPCA61K38/09A61K47/36A61K47/34A61K47/10A61K47/26A61P15/08A61D19/027
Inventor 曾申明杨峰
Owner CHINA AGRI UNIV
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