Bacteriostatic and easy-to-wash foam hand sanitizer and preparation method thereof

A hand sanitizer and easy-to-rinse technology, applied in the field of daily chemical cleaning products, can solve the problems of increasing the difficulty of the preparation process, poor mold inhibitory effect, and poor bacteriostatic spectrum of the hand sanitizer, achieving good cleaning effect, fine and rich foam, Broad antibacterial spectrum

Active Publication Date: 2020-06-05
广州市圣莎拉化妆品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, there are many types of hand sanitizers with AES (lauryl polyoxyethylene ether sulfate) surface active system and soap base system. Due to the strong cleaning and degreasing ability of AES surface active system and soap base system, after washing hands, Hands are usually relatively dry, which brings an unpleasant hand washing experience to users. Long-term use of this hand sanitizer will cause greater irritation to the skin, and the skin is prone to dry, rough and chapped phenomena
In addition, hand sanitizers containing surfactants also have the disadvantage that the foam is difficult to rinse off, and there are still foam residues after repeated washing
[0004] On the other hand, the hand sanitizers on the market do not have a broad antibacterial spectrum. Many hand sanitizers can only inhibit bacteria such as Staphylococcus aureus and Escherichia coli, and the inhibitory effect on mold is very poor. Bacteria spectrum, usually compounded by chemical antibacterial agents and plant antibacterial components, such as the Chinese patent application "A Foam Disinfectant Hand Sanitizer and Its Preparation and Application" with the publication number CN 104840402A, using fatty alcohol polyoxyethylene ether sodium sulfate , Cocamidopropyl Betaine, Sodium Lauryl Sulfate, Polysorbate-20, Essence, Bamboo Charcoal Essential Oil, Triclosan, Ethanol and Water as raw materials for preparation, compounded by anion, zwitterion and non-ionic surfactant Combination, to play a synergistic cleaning effect, and at the same time, bamboo charcoal essential oil and triclosan are compounded to obtain a better bactericidal effect, and it is also effective against Escherichia coli, Candida albicans, Staphylococcus aureus or Pseudomonas aeruginosa
However, the compound plant essential oil not only increases the cost, but also needs to prevent the volatility of the essential oil, which increases the difficulty of the preparation process

Method used

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  • Bacteriostatic and easy-to-wash foam hand sanitizer and preparation method thereof
  • Bacteriostatic and easy-to-wash foam hand sanitizer and preparation method thereof
  • Bacteriostatic and easy-to-wash foam hand sanitizer and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0024] The preparation of acylated catechin in this embodiment comprises the following steps:

[0025] Weigh 250g of epigallocatechin gallate and dissolve it in 1L of water to obtain solution I; weigh 100g of deoxyacetic acid and dissolve it in 0.25L of ethanol to obtain solution II; mix solution I and solution II and add 1g of p-toluenesulfonic acid, Stir and mix well, and react at 100°C for 4 hours under the protection of nitrogen. After the reaction, 3 times the volume of ether is added to the system for extraction. After the ether phase is repeatedly washed with water for 3 times, it is concentrated and dried at low temperature to obtain acylated catechin.

Embodiment 2

[0027] The preparation of acylated catechin in this embodiment comprises the following steps:

[0028] Weigh 300g of epigallocatechin gallate and dissolve it in 1L of water to obtain solution I; weigh 100g of deoxyacetic acid and dissolve it in 0.25L of ethanol to obtain solution II; mix solution I and solution II and add 5g of p-toluenesulfonic acid, Stir and mix well, and react at 80°C for 5 hours under the protection of nitrogen. After the reaction, add 4 times the volume of ether to the system for extraction, wash the ether phase with water for 4 times, concentrate and dry at low temperature to obtain acylated catechin.

Embodiment 3

[0030] The preparation of acylated catechin in this embodiment comprises the following steps:

[0031] Weigh 280g of epigallocatechin gallate and dissolve it in 1L of water to obtain solution I; weigh 100g of deoxyacetic acid and dissolve it in 0.25L of ethanol to obtain solution II; mix solution I and solution II and add 3g of p-toluenesulfonic acid, Stir and mix well, and react at 100°C for 4 hours under the protection of nitrogen. After the reaction, add 5 times the volume of ether to the system for extraction. After the ether phase is repeatedly washed with water for 4 times, it is concentrated and dried at low temperature to obtain acylated catechin.

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PUM

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Abstract

The invention discloses a bacteriostatic and easy-to-wash foam hand sanitizer and a preparation method thereof. The hand sanitizer comprises the following components in percentage by weight: 8-16% ofplant soap base, 1-5% of asparagus fruit extract, 1-5% of emollient, 1-4% of acylated catechin, 0.4-1.6% of stabilizer, 0.1-1% of EDTA-2Na, 0.1-0.3% of essence and the balance of deionized water. Thehand sanitizer is fine and rich in foam, easy to wash, good in cleaning effect, weak in degreasing force, low in irritation, free of dryness after washing, wide in antibacterial spectrum, and good inantibacterial effect on gram negative bacteria, gram positive bacteria and fungi.

Description

technical field [0001] The invention belongs to the technical field of daily chemical washing products, and in particular relates to an antibacterial and easy-to-rinse foam hand sanitizer and a preparation method thereof. Background technique [0002] Modern research has found that many pathogens of people enter the body through the mouth by hand, or take advantage of the situation through contact between hands and nose, eyes and other parts. Therefore, people pay more and more attention to the hygiene of hands. In the past, people have always used soap as a handwashing product, but it is gradually replaced by other handwashing products because soap is easy to slip when used, will soften when exposed to water and high temperature, and is naturally consumed, and it is easy to become a source of bacterial contamination. At present, in order to avoid secondary pollution caused by hand washing products, antibacterial hand sanitizer has become the mainstream. [0003] At presen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/49A61K8/44A61K8/04A61Q19/10A61Q17/00A61P31/04A61P31/10C11D9/02C11D9/26C11D9/30C11D9/38C11D9/50C11D9/60
CPCA61K8/046A61K8/44A61K8/498A61Q17/005A61Q19/10A61K8/9789A61P31/04A61P31/10C11D3/48C11D9/02C11D9/26C11D9/30C11D9/38
Inventor 不公告发明人
Owner 广州市圣莎拉化妆品有限公司
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