Pharmaceutical composition for preventing and treating COVID-19 and preparation method of pharmaceutical composition

Abstract

The invention belongs to the technical field of medicines. The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for preventing and treating COVID-19 (diseases caused by novel coronaviruses) and a preparation method thereof. The pharmaceutical composition comprises active ingredients of mycobacterium vaccae for injection and salbutamol sulfate, and the weight ratio of the mycobacterium vaccae for injection to the salbutamol sulfate is 1: (50-200). The medicine prepared from the medicine composition can adopt an aerosol inhalation treatment mode, and through short-term aerosol inhalation, the compliance of a patient can be improved by providing the medicine with a specific purpose for the patient, so that the patient can take the medicine conveniently, and the medical cost is reduced. The pharmaceutical composition for preventing and treating COVID-19 disclosed by the invention has the advantages that the COVID-19 can be effectively prevented and treated; severe or critical symptoms of patients are relieved, nucleic acid negative conversion time is shortened by about 4 days averagely, treatment time is correspondingly shortened, other respiratory virus infections can be prevented and treated nonspecifically, and a new way and scheme are provided for clinical prevention and treatment of COVID-19 and respiratory virus infections.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for preventing and treating COVID-19 (a disease caused by a novel coronavirus) and a preparation method thereof. Background technique [0002] The country is facing a major outbreak of severe COVID-19 (disease caused by a new type of coronavirus). Although the country quickly isolated and identified it as caused by a new type of coronavirus, due to insufficient or controversial understanding of the source of infection, transmission routes, susceptible hosts, onset characteristics and laws of the new type of coronavirus, coupled with the lack of effective treatment methods, and The mass migration of people during the Spring Festival has led to a sharp increase in the number of infected patients, and the current epidemic prevention and control is still very severe. As of 2020-2-24 24:00 national statistics, a total of 77,658 confirmed case...

AI Technical Summary

Problems solved by technology

At present, in the latest diagnosis and treatment plan ("Diagnosis and Treatment Plan for Pneumonia Infected by Novel Coronavirus (Trial Version 5 and 6)" issued by the National Health and Health Commission on January 27, 2020), nebulized inhalation of α-IFN (500 mg per adult for adults) is recommended. 10,000 U, add 2ml of sterile water for injection, twice a day), but its actual therapeutic effect is still uncertain. Consider its high cost and whether aerosol inhalation of α-IFN can reach the lower respiratory tract and lung tissue

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