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Traditional Chinese medicine composition for preventing and treating Mycoplasma gallisepticum and Escherichia coli mixed infection of poultry and preparation method thereof

A technology of Mycoplasma gallisepticum and Escherichia coli, applied in the field of traditional Chinese medicine, can solve the problems of drug toxicity and side effects, increased drug resistance of Mycoplasma gallisepticum and E. The effect of stable process and product quality

Inactive Publication Date: 2020-07-10
NORTHEAST AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the widespread use of antibiotics has greatly increased the resistance of Mycoplasma gallisepticum and Escherichia coli, and the side effects of drugs will seriously affect the health of poultry

Method used

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  • Traditional Chinese medicine composition for preventing and treating Mycoplasma gallisepticum and Escherichia coli mixed infection of poultry and preparation method thereof
  • Traditional Chinese medicine composition for preventing and treating Mycoplasma gallisepticum and Escherichia coli mixed infection of poultry and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-10

[0032] Examples 1-10 (A-J):

[0033] Prepare 10 kinds of granules for preventing and treating poultry Mycoplasma gallisepticum and Escherichia coli mixed infection according to each composition ratio in the above table, made by the following steps:

[0034] (1) Take each raw material by weight in the table above;

[0035] (2) Decoct Radix Isatidis, Forsythia, Cortex Morus alba, Ginkgo biloba, Licorice and Red Radix in water for 3 times, add 15 times the weight of water each time and decoct for 1 hour, combine the decoction twice, and centrifuge at 4000r / min After 15 minutes, the supernatant was concentrated under reduced pressure to a relative density of 1.30 extract, the extract was vacuum-dried at 90°C until the water content was less than 5% to obtain a dry extract, and the dry extract was crushed into fine powder for later use.

[0036](3) Mix dry paste fine powder and auxiliary materials at a mass ratio of 1:2, use 75wt% ethanol as a wetting agent to make a soft material...

Embodiment 11

[0038] Granules for the prevention and treatment of mixed infection of Mycoplasma gallisepticum and Escherichia coli in poultry:

[0039] (1) Weigh 14g of Radix Isatidis, 7g of Forsythia, 11g of Morus alba, 12g of Ginkgo biloba, 5g of Radix Glycyrrhizae, 3g of Salvia miltiorrhiza;

[0040] (2) Decoct Radix Isatidis, Forsythia, Morus alba, Ginkgo biloba, Licorice and Red Radix in water for 2 times, each time add 15 times the weight of water and decoct for 1.5h, combine the two decoction liquids, at 3000r / min After centrifuging for 15 minutes, the supernatant was concentrated under reduced pressure to a relative density of 1.35 extract, and the extract was vacuum-dried at 80°C until the water content was less than 5% to obtain a dry extract, and the dry extract was crushed into fine powder for later use.

[0041] (3) Mix dry paste fine powder and auxiliary materials at a mass ratio of 1:1, use 80wt% ethanol as a wetting agent, make a soft material, granulate through a 14-mesh si...

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing and treating Mycoplasma gallisepticum and Escherichia coli mixed infection of poultry. The composition comprises 1 to14 parts of radix isatidis, 1 to 7 parts of fructus forsythiae, 1 to 11 parts of cortex mori radicis, 1 to 12 parts of folium ginkgo, 0.3 to 5 parts of liquorice root and 0.3 to 3 parts of radix salviae miltiorrhizae. The method comprises the following steps: mixing all the raw materials, adding water for decocting, combining decoctions, filtering the decoctions, concentrating and drying filtrateto obtain a dry paste, and crushing the obtained dry paste into fine medicinal powder to obtain the composition. The product provided by the invention has an obvious treatment effect on Mycoplasma gallisepticum and Escherichia coli mixed infection. The traditional Chinese medicine composition can inhibit the growth of Mycoplasma gallisepticum and chicken pathogenic Escherichia coli on the one hand, and is compatible with Chinese herbal medicines with the effects of moistening lung to arrest cough, clearing away heat and toxic materials, easing pain, resisting inflammation and the like. All themedicines are matched to achieve the effects of clearing away heat and toxic materials and moistening lung to arrest coughing, thereby treating both symptoms and root causes and achieving preventioneffect. The product provided by the invention is safe and reliable and belongs to an actual non-toxic compound.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for preventing and treating the mixed infection of mycoplasma gallisepticum and Escherichia coli in poultry and a preparation method thereof. Background technique [0002] Mycoplasma gallisepticum is the pathogen of chronic respiratory disease in chickens and infectious sinusitis in turkeys. It causes symptoms such as coughing, tearing, and dyspnea in infected chickens. In severe cases, it can cause air sacitis, perihepatitis, pericarditis, peritonitis, and arthritis. . Adult chickens are mostly recessively infected, and environmental stress can promote the outbreak and spread of the disease. Mycoplasma gallisepticum has no cell wall, and its pathogenic effect mainly depends on the special terminal structure on the cell membrane. It firmly adheres to the surface of the host respiratory mucosa through the adhesion pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/634A61K9/16A61P31/04A61P11/00
CPCA61K9/1652A61K36/16A61K36/195A61K36/315A61K36/484A61K36/537A61K36/605A61K36/634A61K2236/331A61K2236/39A61K2236/51A61P11/00A61P31/04A61K2300/00
Inventor 李继昌吴志勇王燕包佳鑫
Owner NORTHEAST AGRICULTURAL UNIVERSITY
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