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Traditional Chinese medicine composition, extract thereof and application of extract in preventing and treating respiratory virus infection

A technology of composition and extract, which is applied in the direction of drug combination, respiratory diseases, antiviral agents, etc., can solve problems such as uncertainty and complexity of pharmacological action research, and achieve good compatibility, wide application range, and simple process Effect

Active Publication Date: 2020-07-31
温州古木生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the complexity and uncertainty of the research on pharmacological effects due to the diversity of base sources and components of traditional Chinese medicine prescriptions, there is still a large gap in the prevention and treatment of respiratory virus infection diseases and the actual needs of the majority of patients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1: is the application of the extract of traditional Chinese medicine composition in nasal spray for external use.

[0028] Extract preparation of traditional Chinese medicine composition: Weigh 6g of viola chinensis, 20g of Ligustrum lucidum, 10g of lily, 20g of licorice, 10g of gentian, 20g of Moutan cortex, 20g of white fresh cortex, 20g of heterophylla, 20g of rehmannia glutinosa, 6g of cicada slough, Wood butterfly 6g, washed and packed in a decoction bag, placed in a decoction machine, added 20 times pure water according to the weight of the traditional Chinese medicine composition, soaked for 2 hours, extracted at 100 ℃ for 1.5 hours, and stood for 4 hours , take its supernatant and filter it with a 1 micron plate frame to take its filtrate, and then the extract of the traditional Chinese medicine composition can be obtained.

[0029] serial number components Amount added (g) 1 Extract+water of traditional Chinese medicine composition...

Embodiment 2

[0034] Embodiment 2: is the application of the extract of traditional Chinese medicine composition in oral preparation.

[0035] Extract preparation of traditional Chinese medicine composition: Weigh 90g of Viola chinensis, 300g of Ligustrum lucidum, 150g of lily, 300g of licorice, 150g of gentian, 300g of peony bark, 300g of white fresh bark, 300g of heterophylla, 300g of rehmannia, 90g of cicada slough, Wood butterfly 90g, washed and packed in a decoction bag, put in a decoction machine, add 20 times pure water according to the weight of the traditional Chinese medicine composition, soak for 2 hours, extract at 100°C for 1.5 hours, and let it stand for 4 hours , take its supernatant and filter it with a 1 micron plate frame to get its filtrate, heat and evaporate water and concentrate to 3997g to obtain the extract of the traditional Chinese medicine composition.

[0036] serial number components Amount added (g) 1 Extract of Concentrated Chinese Medicine ...

Embodiment 3

[0041] Example 3: The application of the fermented extract which is a traditional Chinese medicine composition in an external nasal spray.

[0042] Preparation of fermented extract of traditional Chinese medicine composition: Weigh 6g of Viola chinensis, 20g of Ligustrum lucidum, 10g of lily, 20g of licorice, 10g of gentian, 20g of peony bark, 20g of white fresh bark, 20g of heterophylla, 20g of rehmannia glutinosa, and 6g of cicada slough 1. Wood butterfly 6g, washed and placed in a fermentation tank, adding 12g of beer yeast (SACCHAROMYCES CEREVISIAE) and 2.5 times the weight of pure water, fermented at 28°C for 72 hours, placed in a decoction machine, added 20 times weight of pure water, extracted at 100°C for 1.5 hours, and after standing for 4 hours, the supernatant was filtered with a 1 micron plate frame to obtain the filtrate to obtain the fermented extract of the traditional Chinese medicine composition.

[0043] serial number components Amount added (g) ...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition, an extract and application of the extract in preventing and treating respiratory virus infection. Philippine violet herb, glossy privet fruit, lily bulbs, liquorice, gentian, tree peony bark, cortex dictamni, pseudostellaria roots, dried rehmannia roots, cicada slough and oroxylum indicum are combined together according to monarch, minister, assistant and guide compatibility so as to obtain the extract and an extract prepared by subjecting the composition to yeast fermentation. The extract can be prepared into an external nasal spray and an oral preparation which have the functions of resisting respiratory virus infection, resisting bacteria, clearing away heat and toxic materials, diminishing inflammation and enhancing immunity, and can be used for effectively preventing and treating respiratory diseases caused by virus infection.

Description

technical field [0001] The invention relates to the technical field of extraction and application of traditional Chinese medicine compositions in the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for preventing and treating respiratory virus infection and its extract and application. Background technique [0002] Respiratory tract virus infection is divided into upper respiratory tract viral infection and lower respiratory tract viral infection. The former manifests as acute rhinitis, pharyngitis and laryngitis, and the latter manifests as acute tracheitis, bronchitis and pneumonia. It is a common clinical disease and can occur in all age groups. Among them, pneumonia caused by coronavirus can cause acute respiratory distress, heart failure, and even death. Respiratory viruses are easy to mutate and cause some new diseases. However, due to the complexity and uncertainty of the study of pharmacological effects due to the d...

Claims

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Application Information

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IPC IPC(8): A61K36/8967A61K9/12A61K9/00A61P11/00A61P31/14A61P31/12A61P31/04A61P37/04A61P29/00A61K35/64
CPCA61K9/0043A61K9/0095A61K35/64A61K36/185A61K36/36A61K36/484A61K36/515A61K36/638A61K36/65A61K36/71A61K36/75A61K36/804A61K36/86A61K36/8967A61K2236/19A61K2236/331A61P11/00A61P29/00A61P31/04A61P31/12A61P31/14A61P37/04A61K2300/00
Inventor 陈克陈万胜
Owner 温州古木生物科技有限公司
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