Anti-acne fucoxanthin-agar oligosaccharide composition, preparation method and application of composition

A technology of agar oligosaccharides and fucoxanthin, applied in the field of human body care, can solve the problems of drug resistance, uneven effect, drug-resistant bacteria, etc., and achieve the effect of controlling the development of acne

Pending Publication Date: 2020-08-14
AQUABRAIN BIOTECH XIAMEN CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most acne-removing cosmetics use plant extracts and Chinese herbal medicine ingredients, and the effects are uneven; while the main ingredients of acne-removing ointments are antibiotics. The biggest problem with antibiotic treatment is the emergence of drug-resistant bacteria. It seems that almost all antibiotics can Cause different degrees of drug resistance in acne-causing bacteria

Method used

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  • Anti-acne fucoxanthin-agar oligosaccharide composition, preparation method and application of composition
  • Anti-acne fucoxanthin-agar oligosaccharide composition, preparation method and application of composition
  • Anti-acne fucoxanthin-agar oligosaccharide composition, preparation method and application of composition

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preparation example Construction

[0061] The present invention provides a kind of preparation method of anti-acne fucoxanthin-agar oligosaccharide composition, it comprises the steps:

[0062] Add agar oligosaccharides and phytoglycosides to water to obtain phase A;

[0063] Fucoxanthin and surfactant are added to the remaining water to obtain phase B;

[0064] Add the phase B into the phase A, stir, add a stabilizer, and age to obtain the composition.

[0065] In a preferred embodiment of the present invention, wherein the method comprises the following steps:

[0066] adding the agar oligosaccharide and the phytoglycoside into water, stirring and dissolving to obtain phase A;

[0067] adding the fucoxanthin and the surfactant to the remaining water, stirring and dissolving to obtain phase B;

[0068] At a rotation speed of 60-300 rpm and a temperature of 20-60° C., the phase B is added to the phase A and stirred, then a stabilizer is added, and the composition is aged overnight to obtain the composition. ...

Embodiment 1

[0078] Preparation of the anti-acne fucoxanthin-agar oligosaccharide composition of embodiment 1 (by 100g total weight)

[0079] (1) Add 1g agar oligosaccharide and 0.5g phytoglycoside into water, stir and dissolve to obtain phase A;

[0080] (2) Add 0.05g fucoxanthin and 3g surfactant to the remaining water, stir and dissolve to obtain phase B;

[0081] (3) Add phase B to phase A at 300 rpm at 40°C and stir for 20 minutes, then add 5 μl stabilizer, continue stirring for 40 minutes, and age overnight to obtain the composition.

[0082] Wherein, agar oligosaccharide is a new agar oligosaccharide, which includes new agarobiose, new agarotetraose and new agarohexexose. In terms of the total weight of the new agar oligosaccharide, the new agarose accounts for 80%, and the new agarose four Sugar accounts for 10%, and new agarosexose accounts for 10%;

[0083] The plant glycoside is baicalin;

[0084] The surfactant is sodium cocoyl glycinate GCS-11;

[0085] Stabilizer is propy...

Embodiment 2

[0087] The preparation of embodiment 2 anti-acne fucoxanthin-agar oligosaccharide composition (by 100g total weight)

[0088] (1) Add 0.8g agarose oligosaccharide and 0.8g phytoglycoside into water, stir and dissolve to obtain phase A;

[0089] (2) Add 0.1g fucoxanthin and 5g surfactant to the remaining water, stir and dissolve to obtain phase B;

[0090] (3) At 200 rpm and a temperature of 50° C., add the phase B into the phase A and stir, then add 8 μl of stabilizer, and age overnight to obtain the composition.

[0091]Wherein, agar oligosaccharide is a new agar oligosaccharide, which includes new agarobiose, new agarotetraose and new agarohexexose. Based on the total weight of the new agar oligosaccharide, the new agarose accounts for 75%, and the new agarose four Sugar accounts for 15%, and new agarosexose accounts for 15%;

[0092] The plant glycoside is baicalin;

[0093] The surfactant is sodium cocoyl glycinate GCS-11;

[0094] Stabilizer is propylene glycol;

[0...

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Abstract

The invention discloses an anti-acne fucoxanthin-agar oligosaccharide composition, a preparation method and application of the composition. The anti-acne fucoxanthin-agar oligosaccharide composition contains agar oligosaccharides, fucoxanthin, plant glycosides, surfactants, stabilizers and water. The growth of two acne pathogenic bacteria, Propionibacterium acnes and Staphylococcus aureus, can beinhibited by the composition provided by the invention, and the development of acne conditions can be effectively controlled.

Description

technical field [0001] The invention relates to the technical field of human body care, in particular to an anti-acne fucoxanthin-agar oligosaccharide composition, a preparation method and an application thereof. Background technique [0002] Acne, also known as pimples, dark sores, and pimples, is a chronic skin disease that occurs in the pilosebaceous glands. Bacteria in the sebaceous follicles play an important role in the inflammatory process of acne. When the sebaceous glands secrete vigorously, the excessive secretions will block the pores and form an anaerobic environment at the hair follicles, allowing the anaerobic Propionibacterium acnes to multiply in large numbers. The lipase secreted by it can decompose human sebum to generate free fatty acid, and at the same time chemoattract inflammatory cells and mediators, and finally induce and aggravate the inflammatory response. Staphylococcus aureus is a common pathogen in humans and can cause many serious infections. ...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K31/336A61K31/351A61K31/7016A61K31/702A61K31/715A61K47/10A61K8/73A61K8/49A61K8/60A61P17/10A61P31/04A61Q17/00A61Q19/00
CPCA61K8/4973A61K8/498A61K8/60A61K8/602A61K8/73A61K31/336A61K31/351A61K31/7016A61K31/702A61K31/7048A61K31/715A61K47/10A61Q17/005A61Q19/00A61P17/10A61P31/04A61K2300/00
Inventor 张春毅何雄飞王斐郑松春王富强
Owner AQUABRAIN BIOTECH XIAMEN CO LTD
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