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A hair growth agent containing spicules

A hair growth agent and spicule technology, applied in the field of hair growth agents containing spicules, can solve the problems of easy failure, high cost, and weak hair growth effect, and achieve the effects of restoring nutrient supply, stimulating blood vessel formation, and increasing enzyme activity

Active Publication Date: 2022-03-15
陕西中鸿科瑞再生医学研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In hair loss diseases, a large number of hair follicles stagnate in the telogen phase and no longer enter the growth phase. This is related to the decrease in the content of cytokines that regulate hair follicle growth and the expression of signal pathways. The gene regulation of hair follicles through the expression of factors and signal pathways will greatly change the hair follicles. The current situation in the field of anti-hair loss, but the current signaling factors and signaling pathways are only in the theoretical stage, and can only be verified at the animal and cell level. How to carry out practical applications has safety, economy and practicality (factors cannot be mass-produced , there are problems with stability, leading to easy failure, high cost, etc.)
[0005] At present, hair loss is a common problem in the whole country and even in the world. There are currently minoxidil, finasteride and other drugs that can be used in treatment. An oral medicine for women
Other types of products such as anti-hair loss cosmetics, medical device products, etc. are almost all external products. Due to the problem of scalp absorption, the product effect is not good

Method used

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  • A hair growth agent containing spicules
  • A hair growth agent containing spicules
  • A hair growth agent containing spicules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A hair growth agent containing spicules, made of the following components by mass fraction: tripeptide-1 copper 0.25%, bee sponge (Sponge Haliclona sp.) spicules 10%, pyrrolidinyl diaminopyrimidine oxide 89.75%.

[0031] Among them, the sponge spicules are spongy spicules with a single shape, a complete structure and a purity of 99%, and the length of the spicules is 30um.

[0032] The hair growth agent containing spicules can be further made into cosmetics, and the specific preparation method is as follows:

[0033] S1. Weigh tripeptide-1 copper, sponge spicules and pyrrolidinyl diaminopyrimidine oxide by mass fraction, and mix them uniformly to obtain a hair growth agent mixture;

[0034] S2. Weigh 15% butylene glycol, 5% glycerin, 10% hair growth agent mixture, 0.5% phenoxyethanol, 1.5% polyquaternium-37, 0.2% disodium EDTA, and 67.8% water according to the mass fraction, and set aside;

[0035] S3. Mix the water, butanediol, glycerin, polyquaternium-37 and disodiu...

Embodiment 2

[0038] A hair growth agent containing spicules is made of the following components by mass fraction: 2.5% of tripeptide-1 copper, 90% of spicules and 7.5% of pyrrolidinyl diaminopyrimidine oxide.

[0039] Among them, the sponge spicule is a spicule with a single shape, a complete structure and a purity of 90%, and the length of the spicule is 800um.

[0040] The hair growth agent containing spongy spicules can be used in combination with medical device products, and the specific preparation method includes the following steps:

[0041] S1. Weigh tripeptide-1 copper, sponge spicules and pyrrolidinyl diaminopyrimidine oxide by mass fraction, and mix them uniformly to obtain a hair growth agent mixture;

[0042] S2. Weigh 8% propylene glycol, 5% glycerin, 50% hair growth agent mixture, 0.5% phenoxyethanol, 1.5% carbomer, 0.2% disodium EDTA and 34.8% water according to the mass fraction, and set aside;

[0043] S3. Mix the water, propylene glycol, glycerin, carbomer and disodium ...

Embodiment 3

[0046] A hair growth agent containing spicules, which is made of the following components by mass fraction: tripeptide-1 copper 0.15%, spicules 55%, pyrrolidinyl diaminopyrimidine oxide 44.85%;

[0047] Among them, the sponge spicules are spongy spicules with a single shape, complete structure and a purity of 95%, and the length of the spicules is 600um.

[0048] The hair growth agent containing spicules can be used in combination with disinfectant components to obtain a product capable of both hair growth and disinfection. The specific preparation method includes the following steps:

[0049] S1. Weigh tripeptide-1 copper, sponge spicules and pyrrolidinyl diaminopyrimidine oxide by mass fraction, and mix them uniformly to obtain a hair growth agent mixture;

[0050] S2. Weigh 15% butylene glycol, 5% glycerin, 10% hair growth agent mixture, 0.089% polyhexamethylene biguanide, 1.5% polyquaternium-37, 0.2% disodium EDTA and 68.211% water according to the mass fraction ,spare;

...

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Abstract

The invention relates to the technical field of hair tonic, and specifically discloses a hair tonic containing spicules, which is made of the following components in terms of mass fraction: tripeptide-1 copper 0.1-2.5%, spicules 5-90%, pyrrole Alkyldiaminopyrimidine Oxide 2‑90%. The hair growth agent containing spicules provided by the present invention can significantly increase the absorption rate of the hair growth agent by the scalp by utilizing the microporous structure formed by the sponge micro-pointers, and play a better hair growth effect.

Description

technical field [0001] The invention relates to the technical field of hair tonic, and specifically discloses a hair tonic containing spicules. Background technique [0002] In recent years, with the in-depth research in the field of hair regeneration, it has been found that hair growth is regulated by hair follicles and the tissues around them, that is, the atrophy and degeneration of hair follicles. The atrophic and degenerated hair follicles cannot absorb nutrients from the surrounding scalp, and the hair naturally no longer grow. Therefore, the key to hair growth is to restore the function of the hair follicles. [0003] The scalp is a part of the skin, and its essence is a biofilm barrier, especially the outermost stratum corneum, which is used to protect the body from the invasion of various harmful substances and exogenous pathogens from the outside. Generally, only a small number of small molecular substances (molecular weight <500Da) can effectively pass throug...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/98A61K8/64A61K8/49A61P17/14A61Q5/12A61Q7/00
CPCA61K8/987A61K8/64A61K8/4953A61Q7/00A61Q5/12A61P17/14
Inventor 李阿峰王清霞明磊国王哲张丹
Owner 陕西中鸿科瑞再生医学研究院有限公司
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