Application of glucoside in promoting in-vitro proliferation of bone marrow mesenchymal stem cells

A bone marrow mesenchymal, in vitro proliferation technology, applied in the field of medicine

Active Publication Date: 2020-10-23
SHENZHEN HANK BIOLOG ENG CO LTD
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  • Application of glucoside in promoting in-vitro proliferation of bone marrow mesenchymal stem cells
  • Application of glucoside in promoting in-vitro proliferation of bone marrow mesenchymal stem cells
  • Application of glucoside in promoting in-vitro proliferation of bone marrow mesenchymal stem cells

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Abstract

The invention discloses application of glucoside in promoting in-vitro proliferation of bone marrow mesenchymal stem cells. The steviol-19-glucoside is a glycoside compound which is widely used and has a natural source. The invention finds that: the steviol-19-glucoside has the effect of promoting hBMSCs proliferation in vitro, and the stem cell characteristics of hBMSCs cannot be obviously reduced. Therefore, the steviol-19-glucoside has the effect of promoting hBMSCs in-vitro proliferation, and has the prospect of being developed into a culture medium for promoting hBMSCs in-vitro proliferation.

Description

technical field [0001] The invention belongs to the field of medicine and relates to stem cells, in particular to the use of steviol-19-glucoside for promoting the proliferation of bone marrow mesenchymal stem cells in vitro. Background technique [0002] Mesenchymal stem cells have been widely used in the field of tissue engineering and regenerative medicine due to their self-renewal ability and multi-directional differentiation potential. They come from a wide range of sources and are easy to operate in vitro. Therefore, mesenchymal stem cell therapy has broad prospects. Among them, human bone marrow Mesenchymal stem cells (hBMSCs) are relatively early, and the research is also abundant. [0003] Due to the relatively difficult way to obtain hBMSCs, the amount of cells is not enough, which limits its clinical application. Therefore, how to effectively improve the proliferation activity of hBMSCs in vitro is particularly important. [0004] Steviol-19-glucoside is a widel...

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IPC IPC(8): C12N5/0775
CPCC12N5/0663C12N2500/30
Inventor 王蒙谭睿陈昕航
Owner SHENZHEN HANK BIOLOG ENG CO LTD
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