The use of Fragaria chinensis or its extract in the preparation of antidepressant drugs

A kind of fragrant green vine and antidepressant technology, which is applied in the field of traditional Chinese medicine, and achieves the effects of good industrialization prospect, convenient source and convenient taking.

Active Publication Date: 2022-06-28
陈乃宏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at present, there is no research on the use of sweet ivy or sweet ivy extracts for the treatment of depression and related diseases caused by it or related research, so how to expand the use of sweet ivy to make it produce the greatest effect Efficacy, to play its due effectiveness, is still the main direction of medical and pharmaceutical research

Method used

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  • The use of Fragaria chinensis or its extract in the preparation of antidepressant drugs
  • The use of Fragaria chinensis or its extract in the preparation of antidepressant drugs
  • The use of Fragaria chinensis or its extract in the preparation of antidepressant drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1 Preparation of Fragrance vine extract

[0029] Take 1kg of Cinnamon vulgaris, add 6L of distilled water to soak for 60min, then heat to 80°C for extraction for 60min, filter, and collect the filtrate; add 6L of distilled water to the filter residue and heat to 80°C for extraction for 60min, filter, and collect the filtrate; add 6L of distilled water to the filter residue and heat to 80°C Extract at ℃ for 60 min, filter, and collect the filtrate; combine the three extracts and concentrate to 1.0-1.2 g / mL.

Embodiment 2

[0030] Example 2 Preparation of Fragrant Green vine extract

[0031] Take 1kg of Cinnamon vulgaris, add 6L of distilled water to soak for 60min, then heat to 90°C for extraction for 60min, filter, and collect the filtrate; add 6L of distilled water to the filter residue and heat to 90°C for extraction for 60min, filter, and collect the filtrate; add 6L of distilled water to the filter residue and heat to 90°C Extract at ℃ for 60 min, filter, and collect the filtrate; combine the three extracts and concentrate to 1.0-1.2 g / mL.

Embodiment 3

[0032] Example 3 Preparation of Fragrant Green vine extract

[0033] Take 1kg of Cinnamon vulgaris, add 6L of distilled water to soak for 60min, then heat to 98°C for extraction for 60min, filter, and collect the filtrate; add 6L of distilled water to the filter residue and heat to 98°C for extraction for 60min, filter, and collect the filtrate; add 6L of distilled water to the filter residue and heat to 98°C Extract at ℃ for 60 min, filter, and collect the filtrate; combine the three extracts and concentrate to 1.0-1.2 g / mL.

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PUM

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Abstract

The invention discloses a use of Ivy or its extract in the preparation of antidepressant drugs, said Ivy ( Illigera aromaticfa S.Z.Huang et S.L.Mo ) is the dry cane of Ivy genus Ivy of the family Pagoniaceae, and the Ivy extract is the water extract of Ivy or the organic solvent extract of Ivy, and the extraction method of Ivy extract is: The Chinese ivy is taken, soaked in a solvent, extracted by heating, and concentrated for multiple times of extraction. The present invention finds for the first time that Ivy vine or its extract has obvious antidepressant activity, has the potential of preparing pharmaceutical preparations for preventing or treating depression and related diseases, and the preparation method of the pharmaceutical preparations is simple, the cost is low, and the economic benefits of pharmaceutical preparations it is good.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to the use of Fragrance vines or an extract thereof in the preparation of antidepressant drugs. Background technique [0002] Depression is an affective disorder characterized by lack of interest, low mood, loss of appetite, and sleep disturbance. Due to the aggravation of many stress factors, depression has become a common disease and a high incidence in the current society. At present, there are 340 million depression patients in the world, and there are more than 26 million depression patients in China. Depression brings great mental torment to the patients themselves, and even suicidal behavior in severe cases, and also brings a heavy burden to the family and society. Depression has become a serious public health problem that needs to be solved urgently. [0003] The pathogenesis of depression involves a variety of complex mechanisms, which hav...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61P25/24A61K135/00
CPCA61K36/185A61P25/24A61K2236/331A61K2236/333A61K2236/39
Inventor 陈乃宏楚世峰韦桂宁
Owner 陈乃宏
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