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Liquid dressing formula for treating leuconychia and preparation method of liquid dressing formula

A liquid dressing and onychomycosis technology, applied in the field of medicine, can solve the problems of unsatisfactory treatment effect of onychomycosis, and achieve the effects of good medicinal properties, quick effect, and difficulty in recurrence.

Inactive Publication Date: 2021-01-01
郑虹
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional treatment methods can only kill the fungus on the surface of the nail, but it is difficult to pass through the barriers of the nail plate to kill the pathogenic fungus hidden under the nail bed. Therefore, clinically, the treatment effect of onychomycosis is often unsatisfactory. For this reason we have proposed a kind of liquid dressing formula and preparation method thereof for the treatment of onychomycosis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A method for preparing a liquid dressing formula for treating onychomycosis, specifically comprising the following steps:

[0022] Step 1. Preparation of materials: preparation of raw materials, ethanol 20%-90%, polyethylene glycol 10%-20%, acetylsalicylic acid 3%-10%, polyhexamethylene biguanide hydrochloride 1%-10%, 1%-5% acetic acid, 0.1%-1% povidone-iodine, 0.1%-1% borneol, 0.5%-2% laurocaprine, and a sufficient amount of Vitex bark, Phellodendron cortex, Sophora flavescens, Sperantosperm;

[0023] Step 2. Extraction: Take the Vitex bark, Cortex Phellodendri, Sophora flavescens and Herba Speranciae in step 1, wash them, dry them, grind them into coarse powder, and then add water and low-temperature ultrasonic extraction / concentration into corresponding extracts.

[0024] Step 3. Weigh the extract: quantitatively weigh 0.5%-1% of Vitex bark extract, 0.5%-1% of Phellodendron Phellodendron extract, 0.5%-1% of Sophora flavescens extract, and 0.5%-1% of Speranthema extra...

Embodiment 2

[0028] A method for preparing a liquid dressing formula for treating onychomycosis, specifically comprising the following steps:

[0029] Step 1. Prepare materials: Prepare raw materials, ethanol 25%-90%, polyethylene glycol 14%-20%, acetylsalicylic acid 3%-8%, polyhexamethylene biguanide hydrochloride 1%-8%, 2%-3% acetic acid, 0.4%-1% povidone-iodine, 0.4%-1% borneol, 0.5%-2.1% laurocaprine, and a sufficient amount of Vitex bark, Phellodendron cortex, Sophora flavescens, and Sperantospera;

[0030] Step 2. Extraction: Take the vetex bark, Phellodendron cortex, Sophora flavescens, and Speranthema fragrans in step 1, wash them, dry them, grind them into coarse powder, and then add water and low-temperature ultrasonic extraction / concentration into corresponding extracts.

[0031] Step 3. Weigh the extract: quantitatively weigh 0.5%-1% of Vitex bark extract, 0.5%-1% of Phellodendron Phellodendron extract, 0.5%-1% of Sophora flavescens extract, and 0.5%-1% of Speranthema extract ...

Embodiment 3

[0035] A method for preparing a liquid dressing formula for treating onychomycosis, specifically comprising the following steps:

[0036] Step 1. Preparation of materials: preparation of raw materials, polyethylene glycol 12%-20%, ethanol 23%-90%, acetylsalicylic acid 3%-9%, polyhexamethylene biguanide hydrochloride 1%-9%, 2%-4% acetic acid, 0.3%-1% povidone-iodine, 0.3%-1% borneol, 0.5%-2.2% laurocaprine, and a sufficient amount of Vitex bark, Phellodendron cortex, Sophora flavescens, Sperantospermii;

[0037] Step 2. Extraction: Take the vetex bark, Phellodendron cortex, Sophora flavescens, and Speranthema fragrans in step 1, wash them, dry them, grind them into coarse powder, and then add water and low-temperature ultrasonic extraction / concentration into corresponding extracts.

[0038] Step 3. Weigh the extract: quantitatively weigh 0.5%-1% of Vitex bark extract, 0.5%-1% of Phellodendron Phellodendron extract, 0.5%-1% of Sophora flavescens extract, and 0.5%-1% of Speranthe...

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PUM

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Abstract

The invention discloses a liquid dressing formula for treating leuconychia and a preparation method of the liquid dressing formula, and relates to the field of medicine and pharmacology. The liquid dressing formula for treating leuconychia and the preparation method of the liquid dressing formula aim to solve the problems that leuconychia is not prone to be radically treated through a traditionalexternal medicine for treating leuconychia and prone to relapse. The liquid dressing formula for treating leuconychia comprises the following raw materials of, in percentage by weight, 20%-90% of ethanol, 10%-20% of polyethylene glycol, 3%-10% of acetylsalicylic acid, 1%-10% of polyhexamethylene biguanide hydrochloride, 1%-5% of acetic acid, 0.1%-1% of povidone iodine, 0.1%-1% of borneol, 0.5%-1%of golden larch bark extract, 0.5%-1% of cortex phellodendri extract, 0.5%-1% of radix sophorae flavescentis extract, 0.5%-1% of garden balsam stem extract and 0.5%-2% of laurocapram. According to theliquid dressing formula for treating leuconychia and the preparation method of the liquid dressing formula, the extracts obtained by extracting golden larch bark, cortex phellodendri, radix sophoraeflavescentis and garden balsam stem through low-temperature ultrasonic waves retain the effective components to the maximum extent to exert the drug effect, and the product is prepared into a liquid dressing, so that the effect taking speed is high, and relapse is not prone to happen after healing.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a liquid dressing formula for treating onychomycosis and a preparation method thereof. Background technique [0002] Onychomycosis, also known as onychomycosis and onychomycosis, is an infection caused by fungi on the nail bed, and highly proliferates and destroys the structure of the nail and the function of the nail bed. Onychomycosis not only affects the appearance, but is also easy to infect other parts of the body, and it is also easy to form cross-infection with family members. Onychomycosis recurs, persists for a long time, and is even called a world problem. Traditional treatment methods can only kill the fungus on the surface of the nail, but it is difficult to pass through the barriers of the nail plate to kill the pathogenic fungus hidden under the nail bed. Therefore, clinically, the treatment effect of onychomycosis is often unsatisfactory. For this reason we have proposed ...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/10A61K47/10A61K47/22A61P17/00A61P31/10A61K31/616A61K31/785A61K31/79A61K33/18
CPCA61K9/0014A61K9/10A61K31/616A61K31/785A61K31/79A61K33/18A61K36/15A61K36/185A61K36/47A61K36/489A61K36/756A61K47/10A61K47/22A61P17/00A61P31/10A61K2300/00
Inventor 郑虹
Owner 郑虹
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