Application evaluation device for paclitaxel liposome
An evaluation device, liposome technology, applied in application, medical science, diagnosis and other directions, can solve the problems of low accuracy, lack of evaluation and classification methods, etc., to achieve accuracy, clinical reference significance, and accuracy. Effect
Active Publication Date: 2021-04-09
CHONGQING MEDICAL & PHARMA COLLEGE
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Problems solved by technology
When evaluating adverse reactions, it is usually recorded through the visual feedback of patients at present. The accuracy of this method of evaluation is low, especially for muscle and joint pain. At present, there is no evaluation and grading method to judge the degree of muscle and joint pain.
Method used
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Embodiment 1
[0033] This embodiment is basically as attached figure 1 , image 3Shown: the application evaluation device of paclitaxel liposome, including a base 1 and a back support mechanism and a knee joint bending test mechanism respectively arranged at both ends of the base 1 . A layer of elastic pad 2 is sewn on the base 1, and the height of the base 1 can be adjusted. The elastic pad 2 in this embodiment is a sponge pad with rubber on the surface. The bottom of the base 1 is welded with an electric telescopic rod 3. The structure and driving method of 3 are all prior art, and will not be repeated here.
[0034] The back support mechanism includes a backboard 4, on which a layer of elastic pad 2 is sewn, and the backboard 4 is rotatably connected with an armrest 5, and the armrest 5 rotates upwards until it fits on the side of the backboard 4, and can also be rotated downward. to present figure 1 status shown. combine Figure 4 As shown, the left end of the base 1 is rotatably c...
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The invention relates to the field of application of paclitaxel liposome, and discloses an application evaluation device for paclitaxel liposome. The application evaluation device comprises a base, a back supporting mechanism and a knee joint bending testing mechanism, wherein the back supporting mechanism and the knee joint bending testing mechanism are arranged at the two ends of the base respectively; a first adjusting assembly is arranged between the back supporting mechanism and the base, and a second adjusting assembly is arranged between the knee joint bending testing mechanism and the base; the second adjusting assembly comprises a first supporting shaft rotationally connected to the end of the base, the knee joint bending testing mechanism is fixedly connected to the first supporting shaft, one end of the first supporting shaft is coaxially and fixedly connected with a wire disc, a worm meshed with the wire disc is rotationally connected to the base, and the worm is perpendicular to the first supporting shaft; and a locking assembly used for limiting the position of the first supporting shaft is arranged on the base, and an angle indication dial is arranged on the base. The application evaluation device fills the blank in the current market and clinic, and compared with the mode that the application effect is evaluated only through subjective expression of a subject, the result tested and recorded through the device has more clinical reference significance.
Description
technical field [0001] The invention relates to the application field of paclitaxel liposome, in particular to an application evaluation device of paclitaxel liposome. Background technique [0002] Paclitaxel is a kind of complex diterpenoid compound extracted from the bark of Taxus brevifolia. The pre-mitotic (G2 phase) and mitotic phase (M phase) of the tumor cell cycle prevents microtubules from forming spindles and spindle filaments during mitosis, inhibits cell mitosis, and makes the dynamics of cells abnormal, thereby preventing the division of tumor cells and proliferation; it has a strong killing effect on a variety of tumor cells, including lung cancer, intestinal cancer, melanoma, breast cancer, and ovarian cancer in vitro experiments, and is known as a major breakthrough in tumor treatment in the 1990s. However, the solubility of paclitaxel in water is very low, and the polyoxyethylene castor oil (Cremophor EL) and absolute ethanol often added in its injection ca...
Claims
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IPC IPC(8): A61B5/11A61B5/00
CPCA61B5/1118A61B5/4827A61B5/4848
Inventor 兰作平
Owner CHONGQING MEDICAL & PHARMA COLLEGE