Unlock instant, AI-driven research and patent intelligence for your innovation.

A method for improving the accuracy of ki67 index in pathological images

A KI67 and pathological image technology, applied in the medical field, can solve the problems of misjudgment of two types of cells, calculation deviation of KI67 index, etc., and achieve the effect of improving accuracy

Active Publication Date: 2022-07-22
杭州迪英加科技有限公司
View PDF10 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the morphological similarity between lymphocytes and positive tumor cells on pathological images, it is easy for computer-aided interpretation algorithms to misjudge the two types of cells, resulting in serious deviations in the calculation of KI67 indicators

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A method for improving the accuracy of ki67 index in pathological images
  • A method for improving the accuracy of ki67 index in pathological images
  • A method for improving the accuracy of ki67 index in pathological images

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] Hereinafter, exemplary embodiments of the present application will be described in detail with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments of the present application, and it should be understood that the present application is not limited by the example embodiments described herein.

[0033] Application overview

[0034] KI67 is a pathological immunohistochemical technique, and the KI67 index is used clinically to evaluate the degree of tumor malignancy. According to the guidelines, pathologists need to count negative tumor cells and positive tumor cells in no less than ten microscopic fields, and then calculate the ratio of positive tumor cells to all tumor cells and take the average as the KI67 index. At present, the more mature algorithms of computer-aided interpretation mainly include traditional algorithms based on morphology and deep lea...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for improving the accuracy of the KI67 index of a pathological image. A computer-aided discrimination algorithm is used to identify lymphocytes and positive tumor cells on a pathological slice in the current field of view, and the distance between the lymphocytes and the positive tumor cells and the distance between the cells and the pigment The results of the computer-aided interpretation algorithm are corrected by the neighborhood voting method, and positive tumor cells are used to vote for lymphocytes. The lymphocytes have a high probability of being positive tumor cells, thus correcting some tumor cells misjudged as lymphocytes by the computer-aided algorithm, obtaining more accurate cell counting results, and improving the accuracy of KI67 interpretation.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to a method for improving the accuracy of the KI67 index of a pathological image. Background technique [0002] With the penetration of digital construction in the medical industry, the application of computer-aided diagnosis and interpretation in clinical practice has become more and more common. Computer-aided diagnosis has achieved remarkable results in some clinical application scenarios such as intensive repetitive labor and large amount of reading. Ki67 pathological slide interpretation is one of these scenarios. KI67 is a pathological immunohistochemical technique, and the KI67 index is used clinically to evaluate the degree of tumor malignancy. According to the guidelines, pathologists need to count negative tumors and positive tumors in no less than ten microscopic fields, then calculate the ratio of positive tumors to all tumor cells and take the average as the KI67 ind...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/00
CPCG06T7/0012G06T2207/30242G06T2207/30024G06T2207/30096
Inventor 蔡佳桐杨林
Owner 杭州迪英加科技有限公司