A standing wave switching type acoustic flow micro-controlling screening device and its working method

Abstract

The invention discloses a standing wave switching type acoustic flow micro-manipulation screening device and its working method, which comprises a micro-manipulation device, a fixing frame and a base; the micro-manipulation device includes a container and a piezoelectric ceramic module; , including first to fourth side plates and a bottom plate, the first and third side plates are respectively provided with first and second clamping ears parallel to the second side plate in the center of the outer wall; the piezoelectric ceramic module includes The first piezoelectric element group and the second piezoelectric element group on the lower end face; the first and second clamping ears are fixed on the base through a fixing frame. In the present invention, the separation and screening of targets with different diameters is realized by applying simple harmonic voltage signals to the first and second piezoelectric element groups in turn. The invention adopts the micro-manipulation device excited by piezoelectricity to realize the non-destructive and non-contact manipulation of the target object, and improves the interaction between researchers and the target object.

Description

technical field [0001] The invention relates to the field of micro-control and rapid screening of micro-particles, in particular to a standing wave switching type acoustic flow micro-control screening device and a working method thereof. Background technique [0002] In recent years, micromanipulations such as translation, rotation, alignment, sorting and separation of some particles or cells have become very common. There are many means of micro-manipulation, including light photography, dielectrophoresis, magnetic field, acoustic tweezers and so on. Among them, sound field manipulation has attracted widespread attention due to its high-precision drive, better biocompatibility, and non-contact manipulation. It is often used to achieve the classification, migration, rotation, and positioning of particles and cells. Vibration-driven micromanipulation devices, as a means of manipulating the orientation of micron-scale objects such as particles and cells, will have lower opera...

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Problems solved by technology

The defect is that the flow channel has a closed structure except for the inlet and outlet, so it is impossible to realize the interaction between the researcher and the target. Secondly, the size of the flow channel is related to the vibration frequency, resulting in a small size of the flow channel, which cannot realize the manipulation of a large number of targets. At the same time, micro-scale flow channels have higher requirements for processing

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