A kind of olfactory disorder detection kit and preparation method thereof

A detection kit and technology for olfactory disorders, applied in the field of olfactory disorder detection kits and its preparation, can solve the problems of difficulty in representing the characteristics of olfactory functions of contemporary groups, physical and mental economic losses, and high cost, so as to improve the effect of olfactory tests and release Effect, non-volatile and metamorphic effect

Active Publication Date: 2022-06-07
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The high cost prevents the test from being administered in large quantities to exert its effective value
At present, the existing smell tests in the domestic market cannot directly give the test results after the test is completed, and professionals need to further assist in analyzing and interpreting the test results
[0005] In addition, the existing olfactory detection methods in the form of paper and pen records and manual calculations are difficult to meet the requirements of digital data structure and large-scale calculation and analysis required for group-level big data mining, which is manifested in data archiving and demographic correction. The complexity of the process and the rigidity of the detection map depicting the group lead to the inability to update the reference baseline for evaluating the level of olfactory function in time, and it is difficult to represent the olfactory function characteristics of contemporary groups
The evaluation results obtained in this form are used as the basis for risk analysis of related diseases, which will increase the misdiagnosis rate of diseases and cause huge physical and mental economic losses to patients and even non-patients, as well as their families

Method used

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  • A kind of olfactory disorder detection kit and preparation method thereof
  • A kind of olfactory disorder detection kit and preparation method thereof
  • A kind of olfactory disorder detection kit and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) Add 10g of melted metal gallium to the spherical mold, let it solidify, solidify it with forceps, and place it on a tray to dry.

[0021] (2) Weigh 10ml ethanol, put it into a 50mL centrifuge tube, add 0.1g of odor flavor, and gently shake the centrifuge tube so that the odor flavor is evenly dissolved;

[0022] (3) Inject the flavor solution into the metal ball with a syringe.

[0023] (4) Transfer the metal ball to room temperature to dry and then mount on the filter paper, i.e., the kit is obtained.

[0024] Example 1 comprises 12 solid odor blocks, odors are menthol, allicin, naringin, folic acetate, nicotine, citric acid, 2-phenethylethanol, caffeine, limonene, acetic acid, neohesperidin, trimethylamine.

Embodiment 2

[0026] (1) Add 10g of melted metal gallium to the spherical mold, let it solidify, solidify it with forceps, and place it on a tray to dry.

[0027] (2) Weigh 10ml ethanol, put it into a 50mL centrifuge tube, add 1g of odor flavor, and gently shake the centrifuge tube so that the odor flavor is evenly dissolved;

[0028] (3) Inject the flavor solution into the metal ball with a syringe;

[0029] (4) Transfer the metal ball to room temperature to dry and install on the polypropylene cotton sheet, i.e., the kit is obtained.

[0030] Example 2 comprises 12 solid odor blocks, odors are menthol, leafyl acetate, allicin, 2-phenethyl alcohol, acetic acid, nicotine, citric acid, caffeine, limonene, neohesperidin, naringin, trimethylamine.

Embodiment 3

[0032] (1) Add 10g of melted metal gallium to the spherical mold, stand and solidify, solidify with forceps after solidification, and place on a tray to dry;

[0033] (2) Weigh 10ml ethanol, put it into a 50mL centrifuge tube, add 0.01g of odor flavor, and gently shake the centrifuge tube so that the odor flavor is evenly dissolved;

[0034] (3) Inject the flavor solution into the metal ball with a syringe;

[0035] (4) Transfer the metal ball to room temperature to dry and then mount on the filter paper, i.e., the kit is obtained.

[0036] Example 3 comprises 12 solid odor blocks, odors are menthol, leaf glycol acetate, allicin, 2-phenethyl alcohol, acetate, nicotine, citric acid, caffeine, limonene, neohesperidin, naringin, trimethylamine.

[0037] In addition to the key solid odor block, the kit of the present invention further comprises Parkinson's disease / Alzheimer's disease olfactory disorder auxiliary diagnosis card and / or odor selection card, wherein, Parkinson's disease...

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Abstract

The invention discloses a detection kit for smell disorder and a preparation method thereof, belonging to the field of detection kits. The kit of the present invention includes one or more metal wraps and carriers, wherein the metal wrap is a wrap made of metal-wrapped scent essence, and the metal is solid at normal temperature, melts at the temperature of the human body and is harmful to the human body. A non-toxic metal material on the body surface, preferably gallium. The kit of the present invention adopts solid material as the odor carrier and is adapted to the characteristic essence components, which can reduce the concentration loss of the odor essence during transportation and storage, improve detection accuracy, facilitate use and simplify transportation and storage. The performance indicators of similar detection methods are better, especially suitable for the elderly population in China, and can be widely used in the detection of olfactory disorders such as symptom detection of hyposmia, early screening of Alzheimer's disease, auxiliary diagnosis of Parkinson's disease and related products in preparation.

Description

Technical field [0001] The present invention relates to a disorder of smell detection kit and a method of preparation thereof, belonging to the field of detection kits. Background [0002] At the level of medical and health care in China, olfactory abnormalities have not received enough attention, and China's research on human olfaction is still in its infancy. The sense of smell is not a regular physical examination item, there is no census of the ability to smell, and there is no industry standard to regulate the olfactory status of workers engaged in odor-related work (e.g., gas repair, fire and explosion protection, chefs, etc.). On the other hand, in our country, gas explosions, gas poisoning and other accidents are frequent, and tens of millions of citizens are suffering from diseases including nasal diseases (nasal trauma, allergic rhinitis, nasopharyngeal cancer, etc.), neurodegenerative diseases (Alzheimer's disease (AD) and Parkinson's disease (PD)), schizophrenia and o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/00
CPCA61B5/4011A61B5/4088A61B5/4082
Inventor 张昊程洋付海田李子健黄乐兮胡昌进刘宁路雅斐张耀东张淼飒喻慧捷钟文丽
Owner JIANGNAN UNIV
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