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Cosmetic composition for skin protection or skin irritation relief, comprising a mixed extract of portulaca oleracea, folium artemisiae argyi, and rhodiola rosea as an active ingredient

A cosmetic composition and technology for skin irritation, applied in the field of cosmetic composition for skin protection and irritation relief containing mixed extracts of purslane, mugwort leaves and rhodiola rosea as active ingredients, capable of solving atrophic lines, hirsutism, Purpura and other issues

Pending Publication Date: 2021-09-07
SK BIOLAND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently, steroid preparations, topical immunosuppressants, topical antibiotics, and antihistamines are used in the treatment of inflammatory skin diseases. However, in the case of long-term use of the above pharmaceutical preparations, it will cause atrophic lines of skin cracking, skin atrophy, capillary Side effects such as dilatation, steroid acne, hirsutism, and purpura
In particular, if steroids are applied to a large area, the drug will be absorbed through the skin through the whole body. If it is a child, it will hinder the growth, and if it is an adult, it will cause systemic side effects such as osteoporosis.

Method used

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  • Cosmetic composition for skin protection or skin irritation relief, comprising a mixed extract of portulaca oleracea, folium artemisiae argyi, and rhodiola rosea as an active ingredient
  • Cosmetic composition for skin protection or skin irritation relief, comprising a mixed extract of portulaca oleracea, folium artemisiae argyi, and rhodiola rosea as an active ingredient
  • Cosmetic composition for skin protection or skin irritation relief, comprising a mixed extract of portulaca oleracea, folium artemisiae argyi, and rhodiola rosea as an active ingredient

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] Embodiment 1: the preparation of the single extract of purslane, Folium mugwort, Rhodiola rosea

Embodiment 1-1

[0063] Example 1-1: Preparation of Purslane Extract

[0064]4.0 kg of 95% (w / w) ethanol was added to 1.0 kg of washed purslane (raw), and heating extraction was performed at a temperature of 50° C. to 60° C. for 3 hours or more. After fully concentrating the filtrate filtered with activated carbon (CGSP) using a vacuum concentrator, it dried using a vacuum drier, and obtained about 50 g of purslane extract powders.

Embodiment 1-2

[0065] Embodiment 1-2: Preparation of Folium Artemisiae Argyi Extract

[0066] At a temperature of 50° C. to 60° C., 1 kg of above-ground parts of mugwort leaves (dried, mugwort) was immersed in 10.0 kg of 70% (w / w) ethanol for 3 hours to extract. Concentration obtained by concentrating the liquid obtained by filtering the extract under reduced pressure using a solvent mixed with n-Hexane (n-Hexane) and ethyl acetate (Ethyl Acetate) at a ratio of 1:1 to 1:10 (w / w) The liquid was subjected to fractional distillation to obtain ethyl acetate fractions, and the fractions were concentrated under reduced pressure to recover 240 g of powder. Using a mixed solvent of n-hexane and ethyl acetate, the above-mentioned soluble extract of Artemisia argyi was adsorbed on silica filled in a chromatographic column, and silica gel column chromatography was performed using a mixed solvent of n-hexane and ethyl acetate. The eluate was roughly divided into three layers, and after the solvent of N...

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Abstract

The present invention relates to a cosmetic composition for skin protection or skin irritation relief, comprising a mixed extract of portulaca oleracea, folium artemisiae argyi, and rhodiola rosea as an active ingredient. When the composition containing the mixed extract of portulaca oleracea, folium artemisiae argyi and rhodiola rosea according to the present invention is used, it is possible to exhibit significantly improved skin barrier improving effect, inflammatory skin disease improving effect and skin calming effect compared to each individual extract. The mixed extract can be used as a cosmetic composition for skin protection, skin irritation relief, or skin calming.

Description

technical field [0001] The present invention relates to a cosmetic composition for skin protection and relief of skin irritation, comprising a mixed extract of purslane, mugwort leaves and rhodiola rosea as active ingredients. Background technique [0002] The skin, as the outermost organ existing in the human body, functions as an essential barrier to protect the human body by protecting moisture in the body and blocking invading agents from the outside. The factors that cause skin inflammation or irritation include physical and chemical stimuli, allergens, ultraviolet rays, oxidative stress, pathogenic bacteria infection, and the resulting secondary inflammation-related cytokines and chemokines. If the skin irritation is aggravated due to these factors, an inflammatory reaction of the skin can be manifested or an allergic or hypersensitivity skin pattern can be manifested. Inflammation is originally a manifestation of a series of defense purposes to minimize the reaction ...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61Q19/00A61P29/00
CPCA61K8/9789A61Q19/005A61Q19/00A61P29/00A61K2800/5922A61K2800/782A61K2800/59
Inventor 李载硕李受莲朴素延金键勇
Owner SK BIOLAND CO LTD