A kind of embedded particle and its preparation method and application

A technology of granule and embedding agent, which is applied in pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc., can solve the problems of difficulty in increasing bone density, poor taste of health care products, and low stability. , to achieve the effect of long shelf life, good stability and high stability
CN113368068BActive Publication Date: 2022-08-02北京斯利安药业有限公司

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
北京斯利安药业有限公司
Publication Date
2022-08-02

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Abstract

The present application discloses an embedded particle and a preparation method and application thereof. The embedded particles include a vitamin K2 inner core, an embedding agent layer I, a vitamin D3 layer, an embedding agent layer II, a calcium source layer, and an embedding agent layer III from the inside to the outside; wherein, the calcium source layer, the vitamin D3 layer, The mass ratio of the vitamin K2 inner core and the embedding agent is 50.5-75: 0.13-0.19: 1.0-1.4: 0.1-5; the quality of the embedding agent is the embedding agent layer I, the embedding agent layer II, the embedding agent The sum of the masses of layer III. The embedded particles have a layer-by-layer embedded structure, with higher stability and longer shelf life.
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Description

technical field

[0001] The application relates to an embedded particle, a preparation method and application thereof, and belongs to the technical field of calcium supplementation products. Background technique

[0002] Osteoporosis is a group of bone diseases caused by a variety of reasons, which can occur in different genders and different ages. It usually manifests as increased bone fragility and susceptibility to fractures due to decreased bone content per unit volume and abnormal bone structure. Pregnant and lactating women are one of the most prone groups to suffer from osteoporosis. The main reasons are: (1) local trauma caused during childbirth, resulting in insufficient bone formation due to vascular and neurotrophic disorders; (2) pregnancy During this period, the fetus ingests maternal calcium to complete bone metabolism, thereby reducing the calcium in the mother; (3) In addition to supplementing their own nutritional needs during pregnancy and lactation, women a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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