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Paeonia lactiflora root extract, skin external preparation containing paeonia lactiflora root extract, and preparation method and application of paeonia lactiflora root extract

A skin external preparation, the technology of peony root, applied in the field of peony root extract, can solve the problems of organic solvent residue, large loss of active ingredients, high energy consumption, etc., achieve the effect of anti-oxidation skin brightness, repair skin barrier, and increase water content

Pending Publication Date: 2021-11-09
云南白药集团上海科技有限公司 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to overcome the problems of large loss of active ingredients, high energy consumption or residual organic solvents when using organic solvents or water as extractants in the prior art to prepare Paeoniae officinalis root extracts by high-temperature reflux extraction and other methods. defects, and provide a peony root extract, skin external preparations containing it and its preparation method and application

Method used

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  • Paeonia lactiflora root extract, skin external preparation containing paeonia lactiflora root extract, and preparation method and application of paeonia lactiflora root extract
  • Paeonia lactiflora root extract, skin external preparation containing paeonia lactiflora root extract, and preparation method and application of paeonia lactiflora root extract
  • Paeonia lactiflora root extract, skin external preparation containing paeonia lactiflora root extract, and preparation method and application of paeonia lactiflora root extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Example 1 Peony Root Extract

[0062] 1. Raw material processing (food grade)

[0063] Fresh peony root: wash the fresh peony root for later use;

[0064] 2. Squeeze the fresh peony root twice at room temperature with a pressure of 130MPa to squeeze out the thick juice of the peony root, then transfer it to a centrifuge, centrifuge at 2000r / min for 20min, and take the supernatant. Material A is obtained;

[0065] 3. Decolorization and deodorization treatment

[0066] Put 200mL of the material A prepared in step 2 into a 250mL conical flask, add 3g of activated carbon and let it stand for adsorption for 24h to reach adsorption equilibrium, transfer it to a centrifuge, and centrifuge at a speed of 5000r / min for 20min to remove the activated carbon. Material B is obtained;

[0067] 4. Suction filtration is performed on the material B obtained in step 3 to further remove solid impurities in the squeezed liquid, and then filter and sterilize with a sterile filter membran...

Embodiment 2

[0068] Embodiment 2 Radix Paeoniae Alba essence

[0069] See Table 1 for the types and parts by weight of the raw materials of the Radix Paeoniae Alba root essence. Mix the high-molecular-weight sodium hyaluronate, sodium hyaluronate, and low-molecular-weight sodium hyaluronate in Table 1 with the same amount of peony root extract respectively, and use a JJ-1A digital speed measuring electric stirrer at a stirring speed of 750r / min. Stir until completely dissolved, then mix the three mixtures, homogenize, and finally add glycerin and stir evenly to obtain the peony root essence.

[0070] Table 1

[0071] raw material Parts by weight (parts) The peony root extract that embodiment 1 makes 97.8 Polymer sodium hyaluronate, >180W 0.1 Sodium hyaluronate, 100-180W 0.05 Low molecular weight sodium hyaluronate, 20-40W 0.05 glycerin 2

Embodiment 3

[0072] Embodiment 3 peony root soothing water

[0073] Step 1: using fresh Paeoniae officinalis as a raw material, adopt the preparation method of Example 1 to prepare Paeoniae officinalis root extract;

[0074] Step 2: Using water as a solvent, dilute the extract of Paeoniae officinalis prepared in Example 1, the mass ratio of fresh Paeoniae officinalis to water is 2:1, and prepare Paeoniae officinalis soothing water.

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Abstract

The invention discloses a paeonia lactiflora root extract, a skin external preparation containing the paeonia lactiflora root extract, and a preparation method and application of the paeonia lactiflora root extract. The preparation method of the paeonia lactiflora root extract comprises the following steps of: squeezing fresh paeonia lactiflora roots, and collecting squeezed liquid to obtain the paeonia lactiflora root extract, wherein no solvent is added in the squeezing process, and the squeezing pressure is 130-180MPa. The preparation process of the paeonia lactiflora root extract and the skin external preparation is simple, no external organic solvent is introduced in the preparation process, and the prepared paeonia lactiflora root extract and the skin external preparation have the effects of being safe, mild, free of irritation to sensitive skin, capable of quickly replenishing water and preserving moisture, repairing skin barrier, resisting inflammation and oxidation, improving skin brightness and the like, and can be widely applied to the field of skin external preparations as soothing water.

Description

technical field [0001] The invention belongs to the technical field of plant extraction, and in particular relates to a peony root extract, an external skin preparation containing the same, a preparation method and application thereof. Background technique [0002] With the improvement of living standards, sensitive skin and acne skin have become the skin problems that plague young people the most. However, this group of people require skin care products that have anti-inflammatory, antibacterial, moisturizing and antioxidant effects. It is also required to be natural and non-irritating to avoid more skin problems. [0003] Peony is the dried root of the perennial herbaceous plant of Paeoniaceae Paeoniaceae in Ranunculaceae. Paeony contains glycosides, terpenoids, flavonoids, phenolic compounds and sugar compounds and other pharmaceutical active ingredients, which have the functions of dilating blood vessels, reducing blood pressure and analgesia, clearing away heat and rel...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/73A61K8/34A61Q19/08A61Q19/00A61P29/00
CPCA61K8/9789A61K8/735A61K8/345A61Q19/00A61Q19/08A61Q19/005A61P29/00A61K2800/805
Inventor 石秀芹翟文丽王一鸣杨杨霍彤权强华安全王昌涛
Owner 云南白药集团上海科技有限公司
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