Preparation method of beautifying and freckle-removing capsule

A capsule and freckle-removing technology, which is applied in the field of preparation of beauty-beautifying and freckle-removing capsules, can solve problems such as ineffective curative effect, slow onset of retinoic acid, and aggravated irritation, and achieve the effect of improving treatment efficiency and shortening the onset time

Pending Publication Date: 2022-04-08
青海晶珠藏药高新技术产业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hydroquinone cream and retinoic acid drugs have certain effects, but there are also shortcomings: when the concentration of hydroquinone cream is high, the curative effect is improved, but the irritation is aggravated, and long-term use can lead to exogenous chloasma; It takes about half a year for the drug to gradually become effective
Jingzhu Jingtian Quban Capsules are selected from plateau medicinal materials, composed of Rhodiola rosea, astragalus, safflower, pearls, etc. It has the effects of promoting blood circulation and Qi, removing freckles and acne, and has achieved definite curative effect in the treatment of chloasma, and the patients are resistant to it. It has good acceptance, but the curative effect of some patients is not obvious after use, or the onset time is slow, so the existing formula needs to be adjusted in order to shorten the time from medication to onset of effect and improve the efficiency of treatment

Method used

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  • Preparation method of beautifying and freckle-removing capsule
  • Preparation method of beautifying and freckle-removing capsule
  • Preparation method of beautifying and freckle-removing capsule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Weigh each component according to the following formula:

[0047]

[0048] Prepare as follows:

[0049] 1) Rhodiola, Radix Polygoni Multiflori and Angelica were reflux extracted three times with 70% ethanol aqueous solution (volume), the first time was extracted with ethanol with 6 times the volume of the medicinal material for 3 hours, and the second time with ethanol with 4 times the volume of the medicinal material for 2 hours , for the third time, extract with ethanol that is 4 times the volume of the medicinal material for 1 hour, combine the extracts, filter, recover the ethanol, and use the obtained solution for later use;

[0050] 2) Process safflower and Rhododendron by steam distillation, take 80g of dried safflower and 200g of Rhododendron, pulverize them with a common pulverizer and pass through a 50-mesh sieve, then mix them evenly, and extract 5 by boiling with 6 times the volume of water hours, using n-hexane to extract the water extract to obtain an ...

Embodiment 2

[0065] The capsules prepared respectively in Example 1 and Comparative Example 1 are used clinically, and their curative effects against the original diseases are compared

[0066] In order to compare the curative effect of the Jingzhu Jingtian Quban Capsule prepared by the present invention and the Jingzhu Jingtian Quban Capsule prepared by the original method, Beijing Jingzhu Traditional Chinese Medicine Hospital included 120 patients with chloasma, and were randomly divided into A group and B group. 60 cases. Wherein Group A was treated with Jingzhu Jingtian Quban Capsule prepared by the present invention (Example 1), and Group B was treated with Jingzhu Jingtian Quban Capsule prepared by the original method (Comparative Example 1). Both groups were given 2 times a day, 4 capsules each time, 3 months as a course of treatment.

[0067] The curative effect judging standard is: the integral is calculated by the sum of the skin lesion area and the skin color score. Lesion are...

Embodiment 3

[0076] The capsules prepared respectively in Example 1 and Comparative Example 1 are used clinically, and their curative effects against new indications are compared

[0077] Beijing Jingzhu Hospital of Traditional Chinese Medicine used the Jingzhu Jingtian Quban Capsule prepared by the present invention in the process of treating chloasma, and found that the medicine also had a curative effect on female patients with primary dysmenorrhea of ​​Qi stagnation and blood stasis type. Preliminary observations were made. Sixty patients with primary dysmenorrhea of ​​qi stagnation and blood stasis were randomly divided into a treatment group and a control group, 30 cases in each group. The treatment group was treated with Jingzhu Jingtian Quban Capsules prepared by the present invention, and the control group was treated with Jingzhu Jingtian Quban Capsules prepared by the original method. They were treated for 3 months, and the curative effect and visual analogue scale (VAS) before ...

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Abstract

The invention discloses a preparation method of a beautifying and freckle-removing capsule. The preparation method comprises the following steps: carrying out reflux extraction on a mixture of rhodiola rosea, polygonum multiflorum and angelica sinensis by adopting an ethanol water solution for at least three times, combining extracting solutions, filtering, and recovering ethanol to obtain a solution containing an extract; treating the mixture of the safflower and the azalea by adopting a steam distillation method to obtain volatile oil and medicine residues; combining the medicine residues, the fructus lycii and the radix astragali, adding water to decoct for at least three times, combining decoctions, and filtering to obtain filtrate; combining the filtrate with the solution containing the extract, and concentrating into thick paste; crushing pearls into pearl powder; uniformly mixing the thick paste with pearl powder, drying, and crushing to obtain fine powder; and uniformly mixing the fine powder with the volatile oil, and filling into capsules. The flos carthami and the rhododendron are used for replacing radix rehmanniae recen and radix rehmanniae praeparata in an original formula, and volatile oil of the flos carthami and the rhododendron is used as a medicine, so that the onset time of the medicine is further shortened, and the effective rate of treatment is improved.

Description

[0001] This application is a divisional application for an invention patent with an application date of November 21, 2018, an application number of 201811391289.9, and an invention title of "A Method for Preparation of Nourishing and Facial Treatment Capsules". technical field [0002] The invention relates to a preparation method of a beauty-beautifying and freckle-removing capsule, which belongs to the technical field of cosmetics. Background technique [0003] Chloasma is an acquired irregular brown pigmentation that occurs on the face. It is generally believed that it is related to endocrine disorders, sun exposure, emotions and other factors. In recent years, the incidence has been on the rise, and the age of onset tends to be younger. [0004] There is currently no effective treatment for this disease. Hydroquinone cream and retinoic acid drugs have certain effects, but there are also shortcomings: when the concentration of hydroquinone cream is high, the curative effe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/9789A61K8/92A61K8/11A61Q19/02A61K36/815A61K9/48A61P17/00A61P15/00A61K35/618
CPCA61P15/00A61P17/00A61Q19/02A61K8/11A61K8/922A61K8/9789A61K8/987A61K9/48A61K35/618A61K36/232A61K36/286A61K36/41A61K36/45A61K36/481A61K36/704A61K36/815A61K2236/39A61K2236/51A61K2236/331A61K2236/333A61K2300/00
Inventor 李方瑞
Owner 青海晶珠藏药高新技术产业股份有限公司
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