Ganoderma lucidum saccharide extract for relieving asthenopia and preparation method thereof

Abstract

The invention relates to a preparation method of a ganoderma lucidum saccharide extract for relieving asthenopia, which comprises the following steps: mixing crushed ganoderma lucidum dried sporocarp with an aqueous solution containing zymophyte and biological enzyme, fermenting and carrying out enzymolysis; adding water, extracting, filtering, decolorizing, concentrating, carrying out alcohol precipitation, and filtering again to obtain a precipitate and a filtrate; recovering ethanol from the filtrate, injecting a concentrated solution into macroporous adsorption resin, collecting an eluted part of water, concentrating, and freeze-drying to obtain a ganoderma lucidum saccharide extract I; adding water to dissolve the precipitate, performing ultrafiltration, collecting trapped fluid, performing vacuum concentration, and performing freeze drying to obtain a ganoderma lucidum saccharide extract II; the ganoderma lucidum saccharide extract II and / or the ganoderma lucidum saccharide extract I are / is ganoderma lucidum saccharide extracts; the compound can remarkably scavenge free radicals, protect retinal epithelial cells, reduce oxidative stress pressure and the like, is prepared into eye drops, eye gel or eye wash and the like, and has the advantages of being mild, free of stimulation, free of toxic and side effects, capable of effectively relieving asthenopia and the like.

Description

technical field [0001] The invention belongs to the field of natural medicines, and in particular relates to a Ganoderma lucidum sugar extract for alleviating visual fatigue and a preparation method thereof. Background technique [0002] With the wide application of video terminals (such as computers, mobile phones, etc.), especially the implementation of VR, 3D games, mobile online games, etc., the number of patients with visual fatigue is increasing. Symptoms of asthenopia, patients usually present with symptoms such as eye pain, dry eyes, eye swelling, eye itching, eye congestion, foreign body sensation in the eyes, blurred vision, double images, photophobia and tearing, which will further lead to vision loss, Glaucoma, cataract, blindness, etc. have seriously affected the vision and quality of life of patients. [0003] Common ways to relieve visual fatigue include drug therapy, refractive error correction, traditional Chinese medicine treatment, vision training, etc. A...

AI Technical Summary

Problems solved by technology

Among the existing drugs for relieving visual fatigue, chemical ingredients such as naprovir and naphthalene will produce certain side effects. Long-term use will reduce tear secretion, leading to degradation of tear secretion function, and eye drops of such ingredients have adverse effects on cardiovascular Patients with diseases, diabetes, hyperthyroidism, etc. should be used with caution; eye drops containing traditional Chinese medicine ingredients, such as bear bile powder eye drops, Siweizhen layer ice boron eye drops, aescin digitalis double glycoside eye drops, etc., should be used when using It is irritating to some extent, and for some people with allergies, eye itching and eyelid skin swelling will appear after medication; artificial tears are mainly composed of polyvinyl alcohol, sodium carboxymethyl cellulose, sodium hyaluronate, etc. The pressure and pH value are similar to tears, non-irritating, and can relieve the symptoms of dry eyes to varying degrees, but it is only a symptomatic treatment, not a permanent cure

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