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Diffuse axonal injury causing device and using method thereof

A technique of diffuse axonal damage, applied in veterinary surgery, veterinary instruments, medical science, etc., can solve the problems of diffuse axonal damage in animals, which cannot be simulated

Inactive Publication Date: 2022-07-01
MUDANJIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to solve the problem that the current animal (mice) diffuse axonal injury injury experimental device cannot simultaneously realize instantaneous angular acceleration and linear acceleration to cause diffuse axonal injury to animals (mice), and cannot target a variety of To solve the problem of simulating brain injury, and provide a diffuse axonal injury injury device and its use method

Method used

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  • Diffuse axonal injury causing device and using method thereof
  • Diffuse axonal injury causing device and using method thereof
  • Diffuse axonal injury causing device and using method thereof

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0033] Embodiment 1: Combining Figures 1 to 8 Describe this embodiment, a diffuse axonal injury injury device of this embodiment, which includes a base 1, a power system and an experimental platform;

[0034] The power system and the experimental platform are all arranged on the base 1;

[0035] The experimental platform is composed of a rotating mechanism and a sliding and tooth plate mechanism;

[0036] The rotating mechanism is composed of an internal gear ring 21, a gear 22, a connecting shaft 23, four animal placing platforms 24 and an animal placing platform support seat 25;

[0037] The animal placing table support base 25 is composed of a bushing 251 sleeved on the connecting shaft 23, four connecting rods 252, two "L"-shaped support plates 253 and four sleeves 255; two "L" The supporting plates 253 of the “L” shape are arranged opposite to each other. The outer edge of the middle of the bottom of the “L”-shaped supporting plate 253 extends downward to form a slider...

specific Embodiment approach 2

[0044] Specific implementation mode 2: Combining Figures 1 to 8 Illustrating this embodiment, the outer diameter of the rotating shaft 242 in this embodiment is smaller than 1 / 8 of the circumference of the inner gear ring 21 . Others are the same as the first embodiment.

specific Embodiment approach 3

[0045] Specific implementation three: combination Figures 1 to 8 Illustrating this embodiment, the fixed tooth plate 32 and the push tooth plate 33 are arranged in parallel with the two sliding grooves 31 and the two sets of fixing blocks 34 . Others are the same as the first embodiment.

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Abstract

The invention discloses a diffuse axonal injury causing device and a using method thereof, and belongs to the field of traumatic neurosurgery. The problems that an existing animal (mouse) diffuse axonal injury causing experimental device cannot achieve diffuse axonal injury of animals (mice) caused by instantaneous angular acceleration and linear acceleration at the same time, and cannot simulate various brain injury conditions are solved. The diffuse axonal injury causing device comprises a base, a power system and an experimental platform, the experiment platform is composed of a rotating mechanism and a sliding and toothed plate mechanism. The rotating mechanism is composed of an inner gear ring, a gear, a connecting shaft, four animal placing tables and animal placing table supporting seats; the sliding and toothed plate mechanism is composed of two sliding grooves, a fixed toothed plate, a pushing toothed plate and a fixing block. The power system is composed of an electric cylinder, an ejection cylinder and a guide rod.

Description

technical field [0001] The invention belongs to the field of traumatic neurosurgery, and in particular relates to a diffuse axonal injury injury device and a method for using the same. Background technique [0002] Brain injury mainly includes traumatic brain injury and ischemic brain injury, with high disability and fatality rate. Diffuse axonal injury (DAI) is caused by the fact that the brain is subjected to linear velocity or rotational acceleration, causing shearing within the brain tissue, and it is generally believed that rotational acceleration is more likely to be caused than linear acceleration. The diffuse axonal injury in clinical patients is mostly caused by the simultaneous instantaneous angular and linear acceleration of the skull. The existing devices for replicating axonal injury are relatively simple in function, and can only realize rotational acceleration or linear acceleration motion, and cannot realize the most realistic model of axonal injury, and the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D1/00A61D3/00
CPCA61D1/00A61D3/00
Inventor 郝艳坤吴琦刘孝琴安佰柱李爽张黎李玉婷袁辉王文婷刘云双
Owner MUDANJIANG MEDICAL UNIV
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