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Methods of determining concentration of glucose in blood

A technology of glucose concentration and blood, applied in the field of measuring glucose concentration in blood, can solve problems such as inaccuracy

Inactive Publication Date: 2004-01-28
GLUCOSENS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

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Method used

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  • Methods of determining concentration of glucose in blood
  • Methods of determining concentration of glucose in blood
  • Methods of determining concentration of glucose in blood

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Embodiment Construction

[0035] At an initial stage, the present method provides simultaneous determination of total impedance and blood glucose concentration using any invasive method. Measurements are made during periods of increasing and decreasing glucose concentrations.

[0036] The total skin impedance or components of the total impedance can be determined by any suitable method, for example, using high frequency oscillating radiation and measuring the resistance with a capacitive sensor. Russian Utility Model Patent Certificate #9703 describes an example of such a device that allows one to perform assays by the method described above.

[0037] It should be noted that in this specification, the term "total resistance" means not only the total impedance including active and ineffective components, but also each component of skin and subcutaneous tissue resistance respectively, and combinations or derivatives of these components , such as the ratio of effective resistance to inactive resistance. ...

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Abstract

A method of non-invasive determination of a glucose concentration in blood based on the measurements of the total impedance of the skin of a patient is disclosed. The method is based on a linear model of a first order correlation between the glucose concentration and the total impedance, the model taking into account the rate of change of the glucose concentration. The coefficients used in an approximating function are determined at the preliminary stage measurements by an invasive method.

Description

[0001] This application claims priority to US Provisional Patent Application Serial No. 60 / 266,774, filed February 5, 2001, which is hereby incorporated by reference. Background of the invention [0002] The present invention relates to a non-invasive medical detection method for a patient. In particular, the present invention relates to a method for measuring glucose concentration in blood based on impedance. [0003] Some methods of non-invasive determination of glucose concentration in the blood are based on the determination of the total resistance (impedance) or components of the total resistance of a part of the patient's body. Electropermeability change based method for monitoring blood sugar levels. In another example, described by Russian patent 2088927, the determination of glucose concentration in blood is accomplished by changing the inactive impedance of the oscillating circuit, in particular, the measurement of the human response to the oscillating circuit integr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/05A61B5/00A61B5/053A61B5/145
CPCY10T436/104998Y10T436/144444A61B5/053A61B5/14532A61B5/14
Inventor 伊戈尔·A·诺维科夫A·V·克斯洛夫
Owner GLUCOSENS
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