Method of expressing thymys peptide alpha by yeast and use thereof

A technology of yeast expression and thymosin, applied in the fields of biology and genetic engineering, can solve the problems of high cost and high price, and achieve the effect of reducing production cost, avoiding pollution and saving foreign exchange.
CN1472319AInactive Publication Date: 2004-02-04ZHEJIANG UNIV PHARM CO LTD
0 Cites 5 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
ZHEJIANG UNIV PHARM CO LTD
Publication Date
2004-02-04
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

A method for expressing the thymopeptide alpha 1 by yeast includes such steps as using PCR technique to amplify the whole-length gene of thymopeptide alpha 1, enzyme severing at both ends, and cloning it to yeast while stably expressing it in yeast. The expressed thymopeptide alpha 1 with very high bioactivity can be used to treat tumor, viral and immunodeficiency diseases, and hypothymism, or used as vaccine intensifier.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to biological technology, relates to genetic engineering, especially relates to a method for expressing thymosin α1 by yeast, and is suitable for adjuvant treatment of diseases caused by hypofunction of thymus. Background technique

[0002] The thymus is an important immune organ in the body and plays an important role in the development of the lymphatic system and maintaining the normal function of the immune system. Especially in anti-infection, anti-tumor, transplantation and autoimmune diseases, it has special significance. As the body ages, the thymus gradually shrinks and degenerates, and the incidence of tumors, infections, and immune diseases gradually increases. A large number of studies have shown that the calf thymus extract (containing thymosin) can be used as an adjuvant treatment for tumors, infections and other diseases caused by hypofunction of the thymus. However, since the thymus extract of animals is a mixed c...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More