Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides

A technology of composition and factors, applied in the preparation and treatment of subjects suffering from bleeding episodes, drugs for treating subjects with bleeding episodes, preventing their episodes, and promoting the formation of blood coagulation in subjects, which can solve difficult and unsuccessful treatments And other issues
CN1556710AInactive Publication Date: 2004-12-22NOVO NORDISK AS
14 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NOVO NORDISK AS
Publication Date
2004-12-22
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The present invention relates to compositions comprising factor VII or factor VII-related polypeptides and factor XI or factor XI-related polypeptides, and their use for the treatment of bleeding episodes.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to pharmaceutical compositions comprising Factor VII or Factor VII-related polypeptides and Factor XI or Factor XI-related polypeptides. The present invention also relates to the combination of factor VII or factor VII-related polypeptide and factor XI or factor XI-related polypeptide in the preparation of a medicament for treating a subject suffering from bleeding episodes, or preventing their onset. The invention also relates to methods of treating bleeding episodes in a subject and methods of promoting coagulation in a subject. The invention also relates to kits containing these compounds. Background technique

[0002] Hemostasis is initiated by the formation of a complex between tissue factor (TF) exposed to circulating blood following vessel wall injury and circulating FVIIa present in amounts corresponding to approximately 1% of the total FVII protein mass. This complex anchors to TF-bearing cells and activates FX ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More