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Drop pills of honeysuckle flower in use for clearing away heat and toxic materials and preparing method

A technology of Yinhua and heat poison, which is applied in the field of oral preparation of pharmaceutical compositions, can solve the problems of unfavorable overall health level, inconvenient to take or carry, low dissolution rate, etc., achieves benefits such as labor protection and environmental protection, and improves bioavailability. , the effect of accelerated dissolution and absorption

Inactive Publication Date: 2005-08-31
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup oral preparations also have disadvantages such as low drug content, difficulty in taking and measuring accurately, inconvenient taking or carrying, etc.
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0029] Now with several groups of specific examples, the preparation method of Yinhua dripping pills of the present invention will be further described.

[0030] Group 1: Tests with a single matrix

[0031] 1. Preparation of the drug extract: Prepare according to the preparation method 1, and obtain the dry powder of the extract containing the active ingredients of two traditional Chinese medicines such as honeysuckle and honeysuckle for subsequent use;

[0032] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;

[0033] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0034] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Yinhua dripping pills of different specific...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating sore throat, fever, furuncle, sore, etc is prepared from honeysuckle flower and stem.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has heat-clearing and detoxifying effects, and is used for treating diseases such as fever and thirst, sore throat, heat boils and sores, heat poisoning in children, etc. A pharmaceutical composition orally prepared. Background technique [0002] According to the ministerial drug standard WS 3 -Yinhua syrup prepared by the preparation method given in B-2781-97 is a syrup that has heat-clearing and detoxifying effects, and is used to treat fever and thirst, sore throat, heat boils and sores, heat poisoning in children and other diseases It is a kind of oral preparation, which has been clinically verified and has definite curative effect. It is a commonly used drug for clinical and family use to treat such diseases. [0003] The following is the drug standard WS 3 -Recipe and process and brief description given in B-2781-97: [0004] Prescription: Honeysuckle 75g, Honeysuckle 175g...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P11/04A61P17/02
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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