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Blood-fat regulating medicinal composition and use thereof

A composition and blood lipid-regulating technology, which can be applied in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., and can solve problems such as no similar composition medicines on the market.

Inactive Publication Date: 2005-10-12
HANGZHOU XINFU TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] So far, there is no similar composition drug on the market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1 tablet

[0021] Soy Isoflavones

4 tablets (1400mg)

Ginkgo biloba total flavonoids

1400mg in 4 tablets)

Simvastatin

pantethine

Soy Isoflavones

Ginkgo flavonoids

Crystalline Cellulose

Magnesium aluminate metasilicate

Sucrose Fatty Acid Ester

Hydroxypropyl Cellulose

Magnesium stearate

Crospovidone

lactose

20mg

500mg

225mg

-

120mg

-

140mg

48mg

24mg

48mg

Appropriate amount

20mg

500mg

-

225mg

120mg

-

140mg

48mg

24mg

48mg

Appropriate amount

[0022] (2) Method

[0023] Measure the above-mentioned ingredients according to the amount of each of the above-mentioned ingredients, and prepare tablets according to the item "Granules" of the General Provisions of Preparations in the Chinese Pharmacopoeia.

Embodiment 2

[0024] Example 2 Granules

[0025] Soy Isoflavones

[0026] (2) Preparation method: Measure the above-mentioned ingredients according to the amount of each of the above-mentioned ingredients, and prepare granules according to the item "Granules" in the general provisions of the Chinese Pharmacopoeia.

Embodiment 3

[0027] Example 3 Capsules

[0028] Soy Isoflavones

[0029] (2) Preparation method: Measure the above-mentioned ingredients according to the amount of each of the above-mentioned ingredients, and prepare capsules according to the item "Capsules" of the general provisions of the Chinese Pharmacopoeia.

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PUM

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Abstract

A composite medicine for regulating blood fat and treating hyperlipemia is prepared from simavastatin, pantethine, flavone, and pharmacologically acceptable additives. It can also be used to prepare the medicine for decreasing the content of cholesterol in blood.

Description

technical field [0001] The invention relates to a blood lipid improving agent composition, in particular to a composition containing simvastatin, pantethine and flavonoids, and is used in the preparation of blood lipid-regulating medicines such as improving blood cholesterol content. Background technique [0002] Hyperlipidemia characterized by elevated low-density lipoprotein and very low-density lipoprotein can cause atherosclerotic endothelial cell dysfunction, hyperplatelet aggregation, foam cell formation, etc., and is a major risk factor for premature coronary heart disease in humans One, so the blood lipid improving agent has a broad market prospect. [0003] Simvastatin is a fully synthetic novel hydroxymethylglutaryl-CoA reductase inhibitor. It is one of the most effective lipid-lowering drugs at present. This product is well absorbed after oral administration. After absorption, the concentration in the liver is higher than that in other tissues. After extensive f...

Claims

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Application Information

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IPC IPC(8): A61K31/366A61P3/06
Inventor 过鑫富楼宜嘉
Owner HANGZHOU XINFU TECH CO LTD
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